Clinical utility of stem cells for periodontal regeneration

Kim Hynes, Danijela Menicanin, Stan Gronthos, P. Mark Bartold

Research output: Contribution to journalArticlepeer-review

157 Citations (Scopus)

Abstract

The aim of this review is to discuss the clinical utility of stem cells in periodontal regeneration by reviewing relevant literature that assesses the periodontal-regenerative potential of stem cells. We considered and described the main stem cell populations that have been utilized with regard to periodontal regeneration, including bone marrow-derived mesenchymal stem cells and the main dental-derived mesenchymal stem cell populations: periodontal ligament stem cells, dental pulp stem cells, stem cells from human exfoliated deciduous teeth, stem cells from apical papilla and dental follicle precursor cells. Research into the use of stem cells for tissue regeneration has the potential to significantly influence periodontal treatment strategies in the future.

Original languageEnglish
Pages (from-to)203-227
Number of pages25
JournalPeriodontology 2000
Volume59
Issue number1
DOIs
Publication statusPublished or Issued - Jun 2012

ASJC Scopus subject areas

  • Periodontics

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