Clinical effectiveness in everyday practice: Improving outcomes for all patients through a national acute coronary syndrome data collaborative

C. M. Astley, A. M. Tonkin, L. J. Mahar, P. M. Davidson, A. N. Boyden, D. B. Brieger, M. Pradhan, M. George, S. F. Mattschoss, D. P. Chew

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


The management of acute coronary syndromes (ACS) has an extensive and impressive evidence-base with which to guide clinical practice. Despite this, translation to the clinical environment has proved to be challenging and incomplete and can be attributed to patient, provider and system factors. Causes of suboptimal guideline adherence relate to diverse issues, including patient complexity, barriers in knowledge translation of guideline recommendations and a limited capacity within health services. Addressing these factors may enable more effective guideline implementation. In Australia, the infrastructure for clinical data management is fragmented, uncoordinated and often administratively driven, compromising access to important information, which might improve clinical effectiveness. An integrated approach is required to improve clinical effectiveness in ACS care in Australia. Greater access to information both to assist in clinical decision-making and monitoring outcomes may help direct the focus towards understudied populations and improve performance and clinically relevant outcomes. A peer-led initiative based on common datasets, providing rapid feedback, while developing and disseminating a 'toolbox' of proven and sustainable interventions, could improve clinical effectiveness in the Australian management of ACS and provides a rationale for a national ACS registry.

Original languageEnglish
Pages (from-to)206-210
Number of pages5
JournalInternal Medicine Journal
Issue number2
Publication statusPublished - 1 Feb 2011


  • Acute coronary syndrome
  • Evidence-based practice
  • Healthcare quality
  • Quality assurance
  • Standard

ASJC Scopus subject areas

  • Internal Medicine

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