Choroidal infiltrates simulating fundal changes of acute leukemia during hematological recovery following high-dose chemotherapy in acute myelomonocytic leukemia in remission

Kanjaksha Ghosh, Sandip Mitra, Devendra Hiwase

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A young female patient of 18 who was diagnosed to have acute myelomonocytic leukemia (AML M4) developed choroidal infiltrate and fundal changes suggestive of acute leukemia deposits while she was in remission and was recovering from chemotherapy induced myelosuppression. The choroidal infiltrates were associated with peripheral blood and CSF monocytosis. The choroidal lesion resolved on its own in 2 week's time, when the peripheral and CSF monocytosis subsided. Interestingly this patient had pseudo-Chediak Higashi inclusions in leukemic blasts with normal karyotype.

LanguageEnglish
Pages42-45
Number of pages4
JournalAmerican Journal of Hematology
Volume63
Issue number1
DOIs
Publication statusPublished - 13 Jan 2000
Externally publishedYes

Keywords

  • Choroidal infiltrates
  • Fluorescein angiography
  • Myeloblast
  • Pseudo-Chediak Higashi inclusions
  • Retinal hemorrhages

ASJC Scopus subject areas

  • Hematology

Cite this

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abstract = "A young female patient of 18 who was diagnosed to have acute myelomonocytic leukemia (AML M4) developed choroidal infiltrate and fundal changes suggestive of acute leukemia deposits while she was in remission and was recovering from chemotherapy induced myelosuppression. The choroidal infiltrates were associated with peripheral blood and CSF monocytosis. The choroidal lesion resolved on its own in 2 week's time, when the peripheral and CSF monocytosis subsided. Interestingly this patient had pseudo-Chediak Higashi inclusions in leukemic blasts with normal karyotype.",
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T1 - Choroidal infiltrates simulating fundal changes of acute leukemia during hematological recovery following high-dose chemotherapy in acute myelomonocytic leukemia in remission

AU - Ghosh, Kanjaksha

AU - Mitra, Sandip

AU - Hiwase, Devendra

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AB - A young female patient of 18 who was diagnosed to have acute myelomonocytic leukemia (AML M4) developed choroidal infiltrate and fundal changes suggestive of acute leukemia deposits while she was in remission and was recovering from chemotherapy induced myelosuppression. The choroidal infiltrates were associated with peripheral blood and CSF monocytosis. The choroidal lesion resolved on its own in 2 week's time, when the peripheral and CSF monocytosis subsided. Interestingly this patient had pseudo-Chediak Higashi inclusions in leukemic blasts with normal karyotype.

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KW - Fluorescein angiography

KW - Myeloblast

KW - Pseudo-Chediak Higashi inclusions

KW - Retinal hemorrhages

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