Cardiac hemodynamics in men versus women during acute ST-segment elevation myocardial infarction

R. P. Dreyer, J. F. Beltrame, C. Neil, T. Air, R. Tavella, B. Hoffmann, P. K. Pati, D. Di Fiore, M. Arstall, C. Zeitz

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Several biologic and clinical factors contribute to the increased 30-day mortality and re-infarction rate in women with ST-segment elevation myocardial infarction (STEMI). Sex differences in cardiac hemodynamic parameters such as pulmonary capillary wedge pressure (PCWP) have not been examined and might play an important role. The objectives of the present study were to examine whether female sex is an independent determinant of PCWP during acute STEMI and whether an elevated PCWP contributes to all-cause 30-day mortality and re-infarction in women. The clinical, angiographic, and hemodynamic features of 470 consecutive patients with STEMI (n = 135 women) undergoing emergency coronary angiography with right-side heart catheterization were evaluated with respect to sex. Women had an elevated PCWP (20 +/- 8 vs 16 +/- 7 mm Hg, p
Original languageEnglish
Pages (from-to)143-149
Number of pages7
JournalCardiology research
Volume112
Issue number2
DOIs
Publication statusPublished or Issued - 2013
Externally publishedYes

Keywords

  • Aged Cohort Studies Electrocardiography Female *Hemodynamics Humans Male Middle Aged Myocardial Infarction/mortality/*physiopathology Pulmonary Wedge Pressure Recurrence Sex Factors

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