Burning Fat Fuels Leukemic Stem Cell Heterogeneity

Daniel Thomas, Ravindra Majeti

Research output: Contribution to journalShort survey

5 Citations (Scopus)

Abstract

Obese leukemia patients exhibit reduced survival after chemotherapy, suggesting an important role of adipose tissue in disease progression. In this issue of Cell Stem Cell, Ye et al. (2016) reveal metabolic heterogeneity in leukemic stem cell (LSC) subpopulations and show that chemotherapy-resistant CD36+ LSCs co-opt gonadal adipose tissue to support their metabolism and survival.

Original languageEnglish
Pages (from-to)1-2
Number of pages2
JournalCell Stem Cell
Volume19
Issue number1
DOIs
Publication statusPublished - 1 Jul 2016
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Cell Biology

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