Brain fog in postural tachycardia syndrome: an objective cerebral blood flow and neurocognitive analysis

Rachel Wells, Felix Paterson, Stephen Bacchi, Amanda Page, Mathias Baumert, Dennis H. Lau

Research output: Contribution to journalArticle


Background: It remains unclear whether brain fog is related to impaired cerebral blood flow (CBF) in postural tachycardia syndrome (POTS) patients. Methods: We assessed CBF in the posterior cerebral artery (PCA) using transcranial Doppler with visual stimuli in 11 POTS and 8 healthy subjects in the seated position, followed by neurocognitive testing. Results: CBF parameters were similar between the two groups. POTS patients demonstrated significantly longer latency in delayed match to sample response time and greater errors in attention switching task. Conclusions: Impaired short-term memory and alertness may underlie the symptom of brain fog in POTS patients, despite normal CBF.

JournalJournal of Arrhythmia
Publication statusPublished - 1 Jan 2020


  • cerebral blood flow velocity
  • cognitive dysfunction
  • neurovascular coupling
  • postural tachycardia syndrome
  • transcranial Doppler

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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