Bone Marrow Mesenchymal Stem Cells

Songtao Shi, Stan Gronthos

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Postnatal bone marrow tissue is known to contain multipotential bone marrow mesenchymal stem cells (MSCs) with the capacity to develop into various mature marrow stromal elements and associated skeletal tissues. This chapter reviews the properties of clonogenic stromal cell types within postnatal bone marrow tissue and addresses a poorly understood aspect of their cell biology: namely, the developmental relationships between the different bone marrow stromal cell lineages. In particular, evidence for the existence of a multipotential bone marrow MSC is discussed, including an examination of the cellular and molecular characteristics of MSC and potential clinical applications.

Original languageEnglish
Title of host publicationStem Cells in Craniofacial Development and Regeneration
PublisherJohn Wiley and Sons
Pages223-239
Number of pages17
ISBN (Print)9781118279236
DOIs
Publication statusPublished - 26 Mar 2013
Externally publishedYes

Keywords

  • Bone marrow mesenchymal stem cells (MSCs)
  • Bone marrow stromal system
  • Craniofacial defects
  • Postnatal bone marrow tissue

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Shi, S., & Gronthos, S. (2013). Bone Marrow Mesenchymal Stem Cells. In Stem Cells in Craniofacial Development and Regeneration (pp. 223-239). John Wiley and Sons. https://doi.org/10.1002/9781118498026.ch11