Atrial Plasticity

Prashanthan Sanders, Joseph B. Morton, Paul B. Sparks, Jonathan M. Kalman

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


The clinical observation that paroxysmal atrial fibrillation (AF) becomes increasingly frequent and eventually persistent has resulted in animal and human studies to determine the possible substrate that creates and then maintains AF. A number of studies have demonstrated that the atrial substrate has the property of plasticity; that is, adaptation (remodeling) to a varying physiological milieu. In this chapter, we will review aspects of electrical, structural and mechanical remodeling.

Original languageEnglish
Title of host publicationInnovative Management of Atrial Fibrillation
PublisherBlackwell Publishing
Number of pages20
ISBN (Print)1405122099, 9781405122092
Publication statusPublished or Issued - 12 Nov 2007
Externally publishedYes


  • Atrial plasticity
  • Congestive heart failure
  • Electrical remodeling
  • Mechanical remodeling
  • Mitral regurgitation

ASJC Scopus subject areas

  • Medicine(all)

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