Associations between inadequate knee function detected by KOOS and prospective graft failure in an anterior cruciate ligament-reconstructed knee

Lars Petter Granan, Valborg Baste, Lars Engebretsen, Maria C S Inacio

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18 Citations (Scopus)


PURPOSE: First, to evaluate whether the 2 year post-operative Knee injury and Osteoarthritis Outcome Score (KOOS) in primary anterior cruciate ligament reconstructions (ACLRs) was significantly different between patients that did not go on to have a subsequent revision after the 2 year post-operative control and the ones that did. Second, to test whether the "clinically failure" value of KOOS quality of life (QoL) < 44 was indicative of a clinically relevant difference in the risk of subsequent revision ACLR.

METHODS: ACLRs reported to the Norwegian Knee Ligament Registry between June 2004 and December 2009. 5,517 primary ACLRs with at least 2-year follow-up with KOOS QoL before revision surgery.

RESULTS: There were clinically significant differences, adjusted and unadjusted, in both the KOOS Sport and Recreation and QoL subscales in patients with a later revision surgery compared to those that did not have a revision surgery. In adjusted models, the risk of later ACLR revision was 3.7 (95 % CI 2.2-6.0) higher in patients with a 2-year KOOS QoL < 44 compared to patients with a KOOS QoL ≥ 44. For every 10-point reduction in the KOOS QoL, a 33.6 % (95 % CI 21.2-47.5 %) higher risk for later ACLR revision was observed.

CONCLUSIONS: This study reveals an association between inadequate knee function, as measured by KOOS, and a prospective ACL-reconstructed graft failure.

LEVEL OF EVIDENCE: Prognostic study (prospective cohort study), Level II.

Original languageEnglish
Pages (from-to)1135-1140
Number of pages6
JournalKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Issue number4
Publication statusPublished - 1 Apr 2015
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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