An in situ Raman spectroscopy-based microfluidic "lab-on-a-chip" platform for non-destructive and continuous characterization of Pseudomonas aeruginosa biofilms

Jinsong Feng, César De La Fuente-Núñez, Michael J. Trimble, Jie Xu, Robert Hancock, Xiaonan Lu

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Pseudomonas aeruginosa biofilm was cultivated and characterized in a microfluidic "lab-on-a-chip" platform coupled with confocal Raman microscopy in a non-destructive manner. Biofilm formation could be quantified by this label-free platform and correlated well with confocal laser scanning microscopy. This Raman-microfluidic platform could also discriminate biofilms at different developmental stages.

Original languageEnglish
Pages (from-to)8966-8969
Number of pages4
JournalChemical Communications
Volume51
Issue number43
DOIs
Publication statusPublished - 28 May 2015
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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