Advances in imaging specific mediators of inflammatory bowel disease

Nicole Dmochowska, Hannah R. Wardill, Patrick Hughes

Research output: Contribution to journalReview articlepeer-review

10 Citations (Scopus)

Abstract

Inflammatory bowel disease (IBD) is characterized by chronic remitting and relapsing inflammation of the lower gastrointestinal tract. The etiology underlying IBD remains unknown, but it is thought to involve a hypersensitive immune response to environmental antigens, including the microbiota. Diagnosis and monitoring of IBD is heavily reliant on endoscopy, which is invasive and does not provide information regarding specific mediators. This review describes recent developments in imaging of IBD with a focus on positron emission tomography (PET) and single-photon emission computed tomography (SPECT) of inflammatory mediators, and how these developments may be applied to the microbiota.

Original languageEnglish
Article number2471
JournalInternational Journal of Molecular Sciences
Volume19
Issue number9
DOIs
Publication statusPublished or Issued - 1 Sep 2018

Keywords

  • Chemokine
  • Colitis
  • Cytokine
  • Inflammation
  • Inflammatory bowel disease (IBD)
  • Microbiota
  • PET
  • SPECT

ASJC Scopus subject areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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