A demonstration of multiplex biosensing using whispering gallery mode microspheres positioned onto a microstructured optical fiber tip

T. Reynolds, A. François, S. J. Nicholls, T. M. Monro

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Here, we show that multiplexed Whispering Gallery Modes sensing can be achieved using two dye-doped microspheres positioned onto the tip of a Microstructured Optical Fiber. By operating the dye-doped microspheres below their lasing threshold, the individual resonances of each sphere overlap and therefore cannot be distinguished. However, when excited above their lasing threshold results in a de-convoluted spectrum where the resonances belonging to the individual spheres can be determined, enabling the detection of a specific interaction in one resonator and using the second as a dynamic reference, or monitoring different specific interactions with both spheres.

LanguageEnglish
Title of host publicationOptical Diagnostics and Sensing XIV
Subtitle of host publicationToward Point-of-Care Diagnostics
PublisherSPIE
Volume8951
ISBN (Print)9780819498649
DOIs
Publication statusPublished - 2014
EventOptical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics - San Francisco, CA, United States
Duration: 3 Feb 20146 Feb 2014

Other

OtherOptical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics
CountryUnited States
CitySan Francisco, CA
Period3/02/146/02/14

Keywords

  • Biosensors
  • Microstructured Optical Fiber
  • Multiplexing
  • Whispering Gallery Modes

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

Cite this

Reynolds, T., François, A., Nicholls, S. J., & Monro, T. M. (2014). A demonstration of multiplex biosensing using whispering gallery mode microspheres positioned onto a microstructured optical fiber tip. In Optical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics (Vol. 8951). [895110] SPIE. https://doi.org/10.1117/12.2039328
Reynolds, T. ; François, A. ; Nicholls, S. J. ; Monro, T. M. / A demonstration of multiplex biosensing using whispering gallery mode microspheres positioned onto a microstructured optical fiber tip. Optical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics. Vol. 8951 SPIE, 2014.
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Reynolds, T, François, A, Nicholls, SJ & Monro, TM 2014, A demonstration of multiplex biosensing using whispering gallery mode microspheres positioned onto a microstructured optical fiber tip. in Optical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics. vol. 8951, 895110, SPIE, Optical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics, San Francisco, CA, United States, 3/02/14. https://doi.org/10.1117/12.2039328

A demonstration of multiplex biosensing using whispering gallery mode microspheres positioned onto a microstructured optical fiber tip. / Reynolds, T.; François, A.; Nicholls, S. J.; Monro, T. M.

Optical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics. Vol. 8951 SPIE, 2014. 895110.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Reynolds T, François A, Nicholls SJ, Monro TM. A demonstration of multiplex biosensing using whispering gallery mode microspheres positioned onto a microstructured optical fiber tip. In Optical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics. Vol. 8951. SPIE. 2014. 895110 https://doi.org/10.1117/12.2039328