A comparison of mitochondrial respiration and membrane lipid composition in the rat and marmoset following dietary lipid supplementation

Edward J. McMurchie, Robert A. Gibson, John S. Charnock, Graeme H. McIntosh

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21 Citations (Scopus)


1. 1. Rats and marmosets were fed different lipid supplemented diets and the p phospholipid fatty acid composition and the respiration rate of liver and heart mitochondria were determined. 2. 2. For both species, diets of differing lipid saturation had little effect on the ratio of saturated to unsaturated fatty acids in the mitochondrial membranes, however the ω 6/ω 3 unsaturated fatty acid ratio was significantly altered by diets of different lipid saturation. 3. 3. In comparison to animals fed low fat diets, mitochondrial respiration in the marmoset was reduced by high fat diets irrespective of the dietary level of lipid saturation. 4. 4. This effect of high fat diets on mitochondrial respiration was not observed for the rat.

Original languageEnglish
Pages (from-to)817-826
Number of pages10
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Issue number4
Publication statusPublished or Issued - 1 Jan 1984

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Molecular Biology

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