A 2-step deep learning method with domain adaptation for multi-centre, multi-vendor and multi-disease cardiac magnetic resonance segmentation

Jorge Corral Acero, Vaanathi Sundaresan, Nicola Dinsdale, Vicente Grau, Mark Jenkinson

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


Segmentation of anatomical structures from Cardiac Magnetic Resonance (CMR) is central to the non-invasive quantitative assessment of cardiac function and structure. Anatomical variability, imaging heterogeneity and cardiac dynamics challenge the automation of this task. Deep learning (DL) approaches have taken over the field of automatic segmentation in recent years, however they are limited by data availability and the additional variability introduced by differences in scanners and protocols. In this work, we propose a 2-step fully automated pipeline to segment CMR images, based on DL encoder-decoder frameworks, and we explore two domain adaptation techniques, domain adversarial training and iterative domain unlearning, to overcome the imaging heterogeneity limitations. We evaluate our methods on the MICCAI 2020 Multi-Centre, Multi-Vendor & Multi-Disease Cardiac Image Segmentation Challenge training and validation datasets. The results show the improvement in performance produced by domain adaptation models, especially among the seen vendors. Finally, we build an ensemble of baseline and domain adapted networks, that reported state-of-art mean Dice scores of 0.912, 0.857 and 0.861 for left ventricle (LV) cavity, LV myocardium and right ventricle cavity, respectively, on the externally validated Challenge dataset, including several unseen vendors, centers and cardiac pathologies.

Original languageEnglish
Title of host publicationStatistical Atlases and Computational Models of the Heart. MandMs and EMIDEC Challenges - 11th International Workshop, STACOM 2020, Held in Conjunction with MICCAI 2020, Revised Selected Papers
EditorsEsther Puyol Anton, Mihaela Pop, Maxime Sermesant, Victor Campello, Alain Lalande, Karim Lekadir, Avan Suinesiaputra, Oscar Camara, Alistair Young
PublisherSpringer Science and Business Media Deutschland GmbH
Number of pages12
ISBN (Print)9783030681067
Publication statusPublished or Issued - 29 Jan 2021
Event11th International Workshop on Statistical Atlases and Computational Models of the Heart, STACOM 2020 held in Conjunction with MICCAI 2020 - Lima, Peru
Duration: 4 Oct 20204 Oct 2020

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume12592 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349


Conference11th International Workshop on Statistical Atlases and Computational Models of the Heart, STACOM 2020 held in Conjunction with MICCAI 2020


  • Cardiac magnetic resonance
  • Data harmonization
  • Deep learning
  • Domain adaptation
  • Segmentation

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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