• 214 Citations
  • 9 h-Index
20112018
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Personal profile

Research Interests

William is a Senior Research Radiochemist at the Molecular Imaging and Therapy Research Unit. His broad research expertise includes inorganic chemistry, medicinal chemistry and radiochemistry. His current research focus is on clinically relevant radiometals (89Zr, 68Ga, 45Ti, 44mSc and 64Cu). Specifically, he investigates novel production and isolation methods for radiometals, synthesis and characterisation of chelators for encapsulating radiometals and conjugation techniques between radiometal chelators and biological vectors (peptides, proteins and drug-like molecules). 

Prior to joining SAHMRI in 2017, William was undertaking his post-doctoral training at University of Sydney, where he worked in a team that investigated bacterial and protein driven synthesis of siderophores and hydroxamates for radiopharmaceutical and anti-cancer applications.

External positions

School of Chemistry and Physics

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Research Output 2011 2018

  • 214 Citations
  • 9 h-Index
  • 16 Article
  • 4 Poster
  • 1 Review article
1 Citation (Scopus)

Crystal structure of highly glycosylated human leukocyte elastase in complex with an S200 site binding inhibitor

Hochscherf, J., Pietsch, M., Tieu, W., Kuan, K., Abell, A. D., Gütschow, M. & Niefind, K., 1 Aug 2018, In : Acta Crystallographica Section F: Structural Biology Communications. 74, 8, p. 480-489 10 p.

Research output: Contribution to journalArticle

Immuno-PET of innate immune markers CD11b and 1IL-1β detect inflammation in murine colitis.

Dmochowska, N., Tieu, W., Keller, M., Wardill, H. R., Mavrangelos, C., Campaniello, M. A., Takhar, P. & Hughes, P., 2018, In : Journal of Nuclear Medicine. JNUMED/2018/219287.

Research output: Contribution to journalArticle

In vivo PET of innate immune responses in murine DSS colitis

Dmochowska, N., Campaniello, M. A., Mavrangelos, C., Wardill, H. R., Keller, M., Tieu, W. & Hughes, P., 2018.

Research output: Contribution to conferencePoster

3 Citations (Scopus)

The chemical biology and coordination chemistry of putrebactin, avaroferrin, bisucaberin, and alcaligin

Codd, R., Soe, C. Z., Pakchung, A. A. H., Sresutharsan, A., Brown, C. J. M. & Tieu, W., 1 Oct 2018, In : Journal of Biological Inorganic Chemistry. 23, 7, p. 969-982 14 p.

Research output: Contribution to journalReview article

18F-FDG-PET: A non-invasive tool for imaging colitis: Australasian Society for Immunology Annual Scientific Meeting

Dmochowska, N., Campaniello, M. A., Mavrangelos, C., Wardill, H., Keller, M., Tieu, W. & Hughes, D. P., Nov 2017.

Research output: Contribution to conferencePoster