Research output per year
Research output per year
Personal profile
Research Interests
William is a Senior Research Radiochemist at the Molecular Imaging and Therapy Research Unit. His broad research expertise includes inorganic chemistry, medicinal chemistry and radiochemistry. His current research focus is on clinically relevant radiometals (89Zr, 68Ga, 45Ti, 44mSc and 64Cu). Specifically, he investigates novel production and isolation methods for radiometals, synthesis and characterisation of chelators for encapsulating radiometals and conjugation techniques between radiometal chelators and biological vectors (peptides, proteins and drug-like molecules).
Prior to joining SAHMRI in 2017, William was undertaking his post-doctoral training at University of Sydney, where he worked in a team that investigated bacterial and protein driven synthesis of siderophores and hydroxamates for radiopharmaceutical and anti-cancer applications.
External positions
School of Chemistry and Physics
Network
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Research output
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89Zr-pro-MMP-9 F(ab')2 detects colitis induced intestinal and kidney fibrosis
Dmochowska, N., Tieu, W., Keller, M. D., Hollis, C. A., Campaniello, M. A., Mavrangelos, C., Takhar, P. & Hughes, P. A., 23 Nov 2020, In: Scientific reports. 10, 1, p. 20372Research output: Contribution to journal › Article › peer-review
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Advanced resistance studies identify two discrete mechanisms in Staphylococcus aureus to overcome antibacterial compounds that target biotin protein ligase
Hayes, A. J., Satiaputra, J., Sternicki, L. M., Paparella, A. S., Feng, Z., Lee, K. J., Blanco-Rodriguez, B., Tieu, W., Eijkelkamp, B. A., Shearwin, K. E., Pukala, T. L., Abell, A. D., Booker, G. W. & Polyak, S. W., Apr 2020, In: Antibiotics. 9, 4, 165.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Improved non-invasive positron emission tomographic imaging of chemotherapy-induced tumor cell death using Zirconium-89-labeled APOMAB®
Liapis, V., Tieu, W., Rudd, S. E., Donnelly, P. S., Wittwer, N. L., Brown, M. P. & Staudacher, A. H., 17 Nov 2020, In: EJNMMI radiopharmacy and chemistry. 5, 1, p. 27Research output: Contribution to journal › Article › peer-review
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Tumour-associated macrophages process drug and radio-conjugates of the dead tumour cell-targeting APOMAB® antibody
Staudacher, A. H., Liapis, V., Tieu, W., Wittwer, N. L. & Brown, M. P., 10 Nov 2020, In: Journal of Controlled Release. 327, p. 779-787 9 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Analogues of desferrioxamine B (DFOB) with new properties and new functions generated using precursor-directed biosynthesis
Telfer, T. J., Richardson-Sanchez, T., Gotsbacher, M. P., Nolan, K. P., Tieu, W. & Codd, R., 1 Jun 2019, In: BioMetals. 32, 3, p. 395-408 14 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus)