• 222 Citations
  • 9 h-Index
20112019
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Personal profile

Research Interests

William is a Senior Research Radiochemist at the Molecular Imaging and Therapy Research Unit. His broad research expertise includes inorganic chemistry, medicinal chemistry and radiochemistry. His current research focus is on clinically relevant radiometals (89Zr, 68Ga, 45Ti, 44mSc and 64Cu). Specifically, he investigates novel production and isolation methods for radiometals, synthesis and characterisation of chelators for encapsulating radiometals and conjugation techniques between radiometal chelators and biological vectors (peptides, proteins and drug-like molecules). 

Prior to joining SAHMRI in 2017, William was undertaking his post-doctoral training at University of Sydney, where he worked in a team that investigated bacterial and protein driven synthesis of siderophores and hydroxamates for radiopharmaceutical and anti-cancer applications.

External positions

School of Chemistry and Physics

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Research Output 2011 2019

  • 222 Citations
  • 9 h-Index
  • 21 Article
  • 4 Poster
  • 1 Review article

Analogues of desferrioxamine B (DFOB) with new properties and new functions generated using precursor-directed biosynthesis

Telfer, T. J., Richardson-Sanchez, T., Gotsbacher, M. P., Nolan, K. P., Tieu, W. & Codd, R., 1 Jun 2019, In : BioMetals. 32, 3, p. 395-408 14 p.

Research output: Contribution to journalArticle

Exploring hydroxamic acid inhibitors of HDAC1 and HDAC2 using small molecule tools and molecular or homology modelling

Daniel, L., Gotsbacher, M. P., Richardson-Sanchez, T., Tieu, W. & Codd, R., 2 Aug 2019, In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Immuno-PET of innate immune markers CD11b and IL-1b detects inflammation in murine colitis

Dmochowska, N., Tieu, W., Keller, M. D., Wardill, H. R., Mavrangelos, C., Campaniello, M. A., Takhar, P. & Hughes, P., 1 Jun 2019, In : Journal of Nuclear Medicine. 60, 6, p. 858-863 6 p.

Research output: Contribution to journalArticle

Rapid and automated production of [68Ga]gallium chloride and [68Ga]Ga-DOTA-TATE on a medical cyclotron

Tieu, W., Hollis, C. A., Kuan, K., Takhar, P., Stuckings, M., Spooner, N. & Malinconico, M., 1 Jul 2019, In : Nuclear Medicine and Biology. 74-75, p. 12-18 7 p.

Research output: Contribution to journalArticle

Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads

Lee, K. J., Tieu, W., Blanco-Rodriguez, B., Paparella, A. S., Yu, J., Hayes, A., Feng, J., Marshall, A. C., Noll, B., Milne, R., Cini, D., Wilce, M. C. J., Booker, G. W., Bruning, J. B., Polyak, S. W. & Abell, A. D., 21 Aug 2019, In : ACS Chemical Biology.

Research output: Contribution to journalArticle