Research Output per year
Research Output per year
Personal profile
Research Interests
William is a Senior Research Radiochemist at the Molecular Imaging and Therapy Research Unit. His broad research expertise includes inorganic chemistry, medicinal chemistry and radiochemistry. His current research focus is on clinically relevant radiometals (89Zr, 68Ga, 45Ti, 44mSc and 64Cu). Specifically, he investigates novel production and isolation methods for radiometals, synthesis and characterisation of chelators for encapsulating radiometals and conjugation techniques between radiometal chelators and biological vectors (peptides, proteins and drug-like molecules).
Prior to joining SAHMRI in 2017, William was undertaking his post-doctoral training at University of Sydney, where he worked in a team that investigated bacterial and protein driven synthesis of siderophores and hydroxamates for radiopharmaceutical and anti-cancer applications.
External positions
School of Chemistry and Physics
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output
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Advanced resistance studies identify two discrete mechanisms in Staphylococcus aureus to overcome antibacterial compounds that target biotin protein ligase
Hayes, A. J., Satiaputra, J., Sternicki, L. M., Paparella, A. S., Feng, Z., Lee, K. J., Blanco-Rodriguez, B., Tieu, W., Eijkelkamp, B. A., Shearwin, K. E., Pukala, T. L., Abell, A. D., Booker, G. W. & Polyak, S. W., Apr 2020, In : Antibiotics. 9, 4, 165.Research output: Contribution to journal › Article
1 Citation (Scopus) -
Analogues of desferrioxamine B (DFOB) with new properties and new functions generated using precursor-directed biosynthesis
Telfer, T. J., Richardson-Sanchez, T., Gotsbacher, M. P., Nolan, K. P., Tieu, W. & Codd, R., 1 Jun 2019, In : BioMetals. 32, 3, p. 395-408 14 p.Research output: Contribution to journal › Article
3 Citations (Scopus) -
Exploring hydroxamic acid inhibitors of HDAC1 and HDAC2 using small molecule tools and molecular or homology modelling
Daniel, L., Gotsbacher, M. P., Richardson-Sanchez, T., Tieu, W. & Codd, R., 15 Sep 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 18, p. 2581-2586 6 p.Research output: Contribution to journal › Article
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Immuno-PET of innate immune markers CD11b and IL-1b detects inflammation in murine colitis
Dmochowska, N., Tieu, W., Keller, M. D., Wardill, H. R., Mavrangelos, C., Campaniello, M. A., Takhar, P. & Hughes, P., 1 Jun 2019, In : Journal of Nuclear Medicine. 60, 6, p. 858-863 6 p.Research output: Contribution to journal › Article
6 Citations (Scopus) -
Rapid and automated production of [68Ga]gallium chloride and [68Ga]Ga-DOTA-TATE on a medical cyclotron
Tieu, W., Hollis, C. A., Kuan, K., Takhar, P., Stuckings, M., Spooner, N. & Malinconico, M., 1 Jul 2019, In : Nuclear Medicine and Biology. 74-75, p. 12-18 7 p.Research output: Contribution to journal › Article
5 Citations (Scopus)