• 1001 Citations
  • 15 h-Index
19982019

Research output per year

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Research Output

  • 1001 Citations
  • 15 h-Index
  • 23 Article
2019

Activation of pruritogenic TGR5, MRGPRA3, and MRGPRC11 on colon-innervating afferents induces visceral hypersensitivity

Castro Kraftchenko, J., Harrington, A., Lieu, T. M., Garcia-Caraballo, S., Maddern, J., Schober, G., O'Donnell, T., Grundy, L., Lumsden, A., Miller, P., Ghetti, A., Steinhoff, M. S., Poole, D. P., Dong, X., Chang, L., Bunnett, N. W. & Brierley, S. M., 17 Oct 2019, In : JCI Insight. 4, 20, e131712.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Serotonin exerts a direct modulatory role on bladder afferent firing in mice

Konthapakdee, N., Grundy, L., O'Donnell, T., Garcia Caraballo, S., Brierley, S., Grundy, D. & Daly, D. M., 14 Sep 2019, In : Journal of Physiology. 597, 21, p. 5247-5264 18 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2018

Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain

Castro, J., Grundy, L., Deiteren, A., Harrington, A., O'Donnell, T., Maddern, J., Moore, J., Garcia-Caraballo, S., Rychkov, G., Yu, R., Kaas, Q., Craik, D. J., Adams, D. J. & Brierley, S., 1 Jun 2018, In : British Journal of Pharmacology. 175, 12, p. 2384-2398 15 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Structure-Activity Studies Reveal the Molecular Basis for GABA B -Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by α-Conotoxin Vc1.1

Sadeghi, M., Carstens, B. B., Callaghan, B. P., Daniel, J. T., Tae, H. S., O'Donnell, T., Castro, J., Brierley, S., Adams, D. J., Craik, D. J. & Clark, R. J., 15 Jun 2018, In : ACS Chemical Biology. 13, 6, p. 1577-1587 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2017

Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways

Bellono, N. W., Bayrer, J. R., Leitch, D. B., Castro, J., Zhang, C., O'Donnell, T. A., Brierley, S. M., Ingraham, H. A. & Julius, D., 29 Jun 2017, In : Cell. 170, 1, p. 185-198.e16

Research output: Contribution to journalArticle

173 Citations (Scopus)
2015

Neuropeptide W modulation of gastric vagal afferent mechanosensitivity: Impact of age and sex

Li, H., Frisby, C. L., O'Donnell, T. A., Kentish, S. J., Wittert, G. A. & Page, A. J., 1 Aug 2015, In : Peptides. 71, p. 141-148 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

TRPV1 channels and gastric vagal afferent signalling in lean and high fat diet induced obese mice

Kentish, S. J., Frisby, C. L., Kritas, S., Li, H., Hatzinikolas, G., O'Donnell, T. A., Wittert, G. A. & Page, A. J., 18 Aug 2015, In : PLoS ONE. 10, 8, e0135892.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2014
26 Citations (Scopus)

Diet-dependent modulation of gastro-oesphageal vagal afferent mechanosensitivity by endogenous nitric oxide

Kentish, S. J., O'Donnell, T. A., Wittert, G. A. & Page, A. J., 1 Aug 2014, In : Journal of Physiology. 592, 15, p. 3287-3301 15 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2013

Gastric vagal afferent modulation by leptin is influenced by food intake status

Kentish, S. J., O'Donnell, T. A., Isaacs, N. J., Young, R. L., Li, H., Harrington, A. M., Brierley, S. M., Wittert, G. A., Blackshaw, L. A. & Page, A. J., 1 Apr 2013, In : Journal of Physiology. 591, 7, p. 1921-1934 14 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Modulation of murine gastric vagal afferent mechanosensitivity by neuropeptide W

Li, H., Kentish, S. J., Kritas, S., Young, R. L., Isaacs, N. J., O'Donnell, T. A., Blackshaw, L. A., Wittert, G. A. & Page, A. J., 1 Oct 2013, In : Acta Physiologica. 209, 2, p. 179-191 13 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2012

Diet-induced adaptation of vagal afferent function

Kentish, S., Li, H., Philp, L. K., O'Donnell, T. A., Isaacs, N. J., Young, R. L., Wittert, G. A., Blackshaw, L. A. & Page, A. J., 1 Jan 2012, In : Journal of Physiology. 590, 1, p. 209-221 13 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)
2009

Nitric oxide as an endogenous peripheral modulator of visceral sensory neuronal function

Page, A. J., O'Donnell, T. A., Cooper, N. J., Young, R. L. & Blackshaw, L. A., 3 Jun 2009, In : Journal of Neuroscience. 29, 22, p. 7245-7255 11 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli

Brierley, S. M., Hughes, P. A., Page, A. J., Kwan, K. Y., Martin, C. M., O'Donnell, T. A., Cooper, N. J., Harrington, A. M., Adam, B., Liebregts, T., Holtmann, G., Corey, D. P., Rychkov, G. Y. & Blackshaw, L. A., 1 Jan 2009, In : Gastroenterology. 137, 6

Research output: Contribution to journalArticle

187 Citations (Scopus)
2008
13 Citations (Scopus)
2007

Ghrelin selectively reduces mechanosensitivity of upper gastrointestinal vagal afferents

Page, A. J., Slattery, J. A., Milte, C., Laker, R., O'Donnell, T., Dorian, C., Brierley, S. M. & Blackshaw, L. A., 1 May 2007, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 292, 5

Research output: Contribution to journalArticle

72 Citations (Scopus)
2006

Inhibition of mechanosensitivity in visceral primary afferents by GABA B receptors involves calcium and potassium channels

Page, A. J., O'Donnell, T. A. & Blackshaw, L. A., 9 Jan 2006, In : Neuroscience. 137, 2, p. 627-636 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2005

Metabotropic glutamate receptors inhibit mechanosensitivity in vagal sensory neurons

Page, A. J., Young, R. L., Martin, C. M., Umaerus, M., O'Donnell, T. A., Cooper, N. J., Coldwell, J. R., Hulander, M., Mattsson, J. P., Lehmann, A. & Blackshaw, L. A., 1 Jan 2005, In : Gastroenterology. 128, 2, p. 402-410 9 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)

Modulation of gastro-oesophageal vagal afferents by galanin in mouse and ferret

Page, A. J., Slattery, J. A., O'Donnell, T. A., Cooper, N. J., Young, R. L. & Blackshaw, L. A., 15 Mar 2005, In : Journal of Physiology. 563, 3, p. 809-819 11 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2000

GABA(B) receptor-mediated effects on vagal pathways to the lower oesophageal sphincter and heart

Ashley Blackshaw, L., Smid, S. D., O'Donnell, T. & Dent, J., 25 May 2000, In : British Journal of Pharmacology. 130, 2, p. 279-288 10 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

P2X purinoceptor-induced sensitization of ferret vagal mechanoreceptors in oesophageal inflammation

Page, A. J., O'Donnell, T. A. & Blackshaw, L. A., 1 Mar 2000, In : Journal of Physiology. 523, 2, p. 403-411 9 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)
1998

Oesophagitis-induced changes in capsaicin-sensitive tachykininergic pathways in the ferret lower oesophageal sphincter

Smid, S. D., Page, A. J., O'Donnell, T., Langman, J., Rowland, R. & Blackshaw, L. A., 1998, In : Neurogastroenterology and Motility. 10, 5, p. 403-411 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)