Timothy Hughes


  • 34463 Citations
  • 76 h-Index
1989 …2020

Research output per year

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Personal profile

Public Profile

Professor Timothy Hughes is the Precision Medicine Theme Leader at SAHMRI and Consultant Haematologist in the Division of Haematology at SA Pathology. He is also the Cancer Council Chair in Cancer Research, Chair of the International Chronic Myeloid Leukemia Foundation (iCMLf) and Fellow of the Australian Academy of Health and Medical Sciences (AAHMS).

Professor Hughes is an international expert in the biology and treatment of leukaemia. He led the establishment of the molecular response criteria that are used world-wide to measure response in chronic myeloid leukaemia (CML) and has led many of the key Global and National trials. His group has successfully developed predictive bioassays and molecular targets that influence the way CML patients are managed world-wide. He has published over 250 papers that have been cited over 40,000 times. 

In October 2017 Professor Hughes was awarded the GSK Award for Research Excellence 2017 for pioneering the use of tyrosine kinase inhibitors (TKIs).

Education/Academic qualification

PhD, Doctor of Medicine , University of New South Wales

… → 1993

Fellowship of the Royal Australasian College of Physicians

… → 1988

Fellowship of the Royal College of Pathologists of Australia

… → 1988

MB BS (Honours), University of New South Wales

… → 1981

External positions

Consultant Haematologist , SA Pathology

Beat Cancer Professor, University of Adelaide

Chair, International CML Foundation


  • Chronic Myeloid Leukaemia
  • Leukaemia
  • Cancer
  • Haematology
  • Treatment Free Remission

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Research Output

Aberrant RAG-mediated recombination contributes to multiple structural rearrangements in lymphoid blast crisis of chronic myeloid leukemia

Thomson, D. W., Shahrin, N. H., Wang, P. P. S., Wadham, C., Shanmuganathan, N., Scott, H. S., Dinger, M. E., Hughes, T. P., Schreiber, A. W. & Branford, S., 1 Aug 2020, In : Leukemia. 34, 8, p. 2051-2063 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia

Hochhaus, A., Baccarani, M., Silver, R. T., Schiffer, C., Apperley, J. F., Cervantes, F., Clark, R. E., Cortes, J. E., Deininger, M. W., Guilhot, F., Hjorth-Hansen, H., Hughes, T. P., Janssen, J. J. W. M., Kantarjian, H. M., Kim, D. W., Larson, R. A., Lipton, J. H., Mahon, F. X., Mayer, J., Nicolini, F. & 14 others, Niederwieser, D., Pane, F., Radich, J. P., Rea, D., Richter, J., Rosti, G., Rousselot, P., Saglio, G., Saußele, S., Soverini, S., Steegmann, J. L., Turkina, A., Zaritskey, A. & Hehlmann, R., Apr 2020, In : Leukemia. 34, 4, p. 966-984 19 p.

Research output: Contribution to journalReview article

26 Citations (Scopus)

High-risk B-cell acute lymphoblastic leukaemia presenting with hypereosinophilia and acquiring a novel PAX5 fusion on relapse

McClure, B. J., Heatley, S. L., Rehn, J., Breen, J., Sutton, R., Hughes, T. P., Suppiah, R., Revesz, T., Osborn, M., White, D., Yeung, D. T. & White, D. L., 1 Jan 2020, (Accepted/In press) In : British Journal of Haematology.

Research output: Contribution to journalLetter

Open Access

Lineage of measurable residual disease in patients with chronic myeloid leukemia in treatment-free remission

Pagani, I. S., Dang, P., Saunders, V. A., Grose, R., Shanmuganathan, N., Kok, C. H., Carne, L., Rwodzi, Z., Watts, S., McLean, J., Braley, J., Altamura, H., Yeung, D. T., Branford, S., Yong, A. S. M., White, D. L., Hughes, T. P. & Ross, D. M., Apr 2020, In : Leukemia. 34, 4, p. 1052-1061 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)