Tim Kuchel


  • 1529 Citations
  • 22 h-Index
1980 …2018
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Personal profile

Public Profile

Dr Tim Kuchel, is the director of the Preclinical, Imaging and Research Laboratories (PIRL) of the South Australian Health and Medical Research Institute (SAHMRI). It is PIRL which hosts the NIF - funded Large Animal Research and Imaging Facility (LARIF). Dr. Kuchel has more than 30 years’ experience with a special interest in imaging modalities, experimental surgery and comparative anaesthesia. The capacity to provide or help develop Large Animal Models of human disease is the core business of LARIF and PIRL, and interactions with industry to add to existing translational medicine capacity are being actively pursued by Dr. Kuchel and his team.

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Research Output 1980 2018

  • 1529 Citations
  • 22 h-Index
  • 59 Article
  • 2 Letter
  • 1 Comment/debate
1 Citation (Scopus)

Adeno-Associated Virus Neutralizing Antibodies in Large Animals and Their Impact on Brain Intraparenchymal Gene Transfer

Wang, D., Zhong, L., Li, M., Li, J., Tran, K., Ren, L., He, R., Xie, J., Moser, R. P., Fraser, C., Kuchel, T., Sena-Esteves, M., Flotte, T. R., Aronin, N. & Gao, G., 14 Dec 2018, In : Molecular Therapy - Methods and Clinical Development. 11, p. 65-72 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Artificial miRNAs Reduce Human Mutant Huntingtin Throughout the Striatum in a Transgenic Sheep Model of Huntington's Disease

Pfister, E. L., Dinardo, N., Mondo, E., Borel, F., Conroy, F., Fraser, C., Gernoux, G., Han, X., Hu, D., Johnson, E., Kennington, L., Liu, P., Reid, S. J., Sapp, E., Vodicka, P., Kuchel, T., Morton, A. J., Howland, D., Moser, R., Sena-Esteves, M. & 4 othersGao, G., Mueller, C., Difiglia, M. & Aronin, N., 1 Jun 2018, In : Human Gene Therapy. 29, 6, p. 663-673 11 p.

Research output: Contribution to journalArticle

Correction: Gestational dietary protein is associated with sex specific decrease in blood flow, fetal heart growth and postnatal blood pressure of progeny (PLoS ONE (2015) 10:4 (e0125694) DOI: 10.1371/journal.pone.0125694)

Hernandez-Medrano, J. H., Copping, K. J., Hoare, A., Wapanaar, W., Grivell, R., Kuchel, T., Miguel-Pacheco, G., Caroline McMillen, I., Rodgers, R. J. & Perry, V. E. A., 1 May 2018, In : PloS one. 13, 5, e0197942.

Research output: Contribution to journalComment/debate

5 Citations (Scopus)

Delivery of siRNA in vitro and in vivo using PEI-capped porous silicon nanoparticles to silence MRP1 and inhibit proliferation in glioblastoma

Tong, W. Y., Alnakhli, M., Bhardwaj, R., Apostolou, S., Sinha, S., Fraser, C., Kuchel, T., Kuss, B. & Voelcker, N. H., 13 Apr 2018, In : Journal of Nanobiotechnology. 16, 1, 38.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Evaluation of relative bioaccessibility leaching procedure for an assessment of lead bioavailability in mixed metal contaminated soils

Wijayawardena, M. A. A., Naidu, R., Megharaj, M., Lamb, D., Thavamani, P. & Kuchel, T., 1 Apr 2017, In : Environmental Technology and Innovation. 7, p. 229-238 10 p.

Research output: Contribution to journalArticle

Activities 2016 2019

  • 1 Consumer Engagament
  • 1 Newsletter
  • 1 Oral presentation

Wildlife Matters

Marianne Keller (Participant), Tim Kuchel (Participant)
Jun 2019

Activity: OtherNewsletter

Diffusion Tensor Imaging of Huntington’s Disease in Sheep at 3T MRI

Erin Batcho (Speaker), Raj Perumal (Speaker), Marianne Keller (Speaker), Tim Kuchel (Speaker), Sundeep Chandra (Speaker), Tom Denney (Speaker), Heather Gray-Edwards (Speaker)
17 Nov 2018

Activity: Talk or presentationOral presentation

NIF/LARIF engagement

Tim Kuchel (Other), Marianne Keller (Other)
2 Aug 2016

Activity: OtherConsumer Engagament