• 25908 Citations
  • 66 h-Index
1992 …2020

Research output per year

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Personal profile

Public Profile

I am a cell biologist with over 28 years experience in the stem cell and musculoskeletal fields and is a pioneer in the isolation, purification and application of mesenchymal stem cells from bone marrow, adipose and dental tissues. My laboratory is focused on identifying epigenetic/ transcriptional factors and signalling pathways that mediate MSC self-renewal, niche maintenance, growth, migration, immunomodulation and multi-differentiation. My research activities have resulted in several highly cited seminal publications with 216 peer-reviewed publications including book chapters/reviews with over 42,000 citations and a h-index of 40 (Google Scholar). I have had 70 invitations to present my research as orals at national and international conferences that have included Society or Institutional financial support. My work in collaboration with Prof Andrew Zannettino has generated 12 stem cell related patents which were used to establish Mesoblast Ltd in 2004, currently supporting multiple FDA approved allogeneic MSC Phase II/ III Human Clinical Trials using our stem cell technology (spinal fusion, fracture repair, osteoarthritis, cardiovascular disease, cancer, immunotherapy). 

Education/Academic qualification

PhD

External positions

Professor of Stem Cell Biology and Regenerative Medicine, University of Adelaide

Keywords

  • Stem Cells
  • Regenerative Medicine
  • Musculoskeletal
  • Dental/ Craniofacial

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Research Output

Characterisation and evaluation of the regenerative capacity of Stro-4+ enriched bone marrow mesenchymal stromal cells using bovine extracellular matrix hydrogel and a novel biocompatible melt electro-written medical-grade polycaprolactone scaffold

Black, C., Kanczler, J. M., de Andrés, M. C., White, L. J., Savi, F. M., Bas, O., Saifzadeh, S., Henkel, J., Zannettino, A., Gronthos, S., Woodruff, M. A., Hutmacher, D. W. & Oreffo, R. O. C., 1 Jul 2020, In : Biomaterials. 247, 119998.

Research output: Contribution to journalArticle

Multispectral characterisation of mesenchymal stem/stromal cells: Age, cell cycle, senescence, and pluripotency

Campbell, J. M., Habibalahi, A., Mahbub, S., Paton, S., Gronthos, S. & Goldys, E., 1 Jan 2020, Label-Free Biomedical Imaging and Sensing (LBIS) 2020. Shaked, N. T. & Hayden, O. (eds.). SPIE, Vol. 11251. 112510F

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Stem cell-directed therapies for osteoarthritis: The promise and the practice

Ng, J., Little, C. B., Woods, S., Whittle, S., Lee, F. Y., Gronthos, S., Mukherjee, S., Hunter, D. J. & Worthley, D. L., 1 Apr 2020, In : Stem Cells. 38, 4, p. 477-486 10 p.

Research output: Contribution to journalReview article

The changing epigenetic landscape of Mesenchymal Stem/Stromal Cells during aging

Cakouros, D. & Gronthos, S., Aug 2020, In : Bone. 137, 115440.

Research output: Contribution to journalArticle