• 3486 Citations
  • 29 h-Index
1983 …2020

Research output per year

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Personal profile

Public Profile

Prof. Simon A. Koblar BMBS, FRACP, PhD is a Professor of Neurology and Neuroscience at the University of Adelaide and a clinician-scientist and with a major interest is Stroke.  He established the Stroke Research Programme (SRP) in 2005, now the major collaboration in stroke research within South Australia.  The SRP is a unique collaboration between the South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and the Central Adelaide Local Health Network (CALHN).  Prof Koblar continues to practice as a Neurologist and Stroke Physician in public and private.  

In 2010 he co-founded the Peter Couche Foundation (PCF), a philanthropic organisation within the University of Adelaide.  The PCF has raised $500,000 to support research in a range of translational preclinical fields, stem cell therapy and reduction of vasogenic oedema follow stroke.  In 2018 he co-founded the Cure for Stroke Australia, a philanthropic foundation aimed to raise funds for stroke research, with A/Professors Tim Kleinig, Jim Jannes and Anne Hamilton-Bruce.

As Director of the SRP, Prof Koblar has led the translation and prioritisation of pathways of Stroke management within SA Health policy.  In 2007 Prof Koblar and A/Profs Jannes and Hamilton-Bruce established TQEH Comprehensive Stroke Unit.  He was involved in establishing the SA Stroke Clinical Network which has continued to the current day in different forms to instruct a coordinate stroke pathway delivery with SA.  With respect to stroke prevention (an SRP research aim), Prof Koblar made direct representation and gave policy support to the National Stroke Foundation to run a successful bid to the Federal Government to support the FAST media campaign to the sum of $2 million.  In 2014, Prof Koblar started planning for the TOOTH Clinical Stroke Trial, a phase 1 clinical study of autologous human adult stem cell therapy for chronically disabled stroke patients.

Since 2008, Prof Koblar has been Patron for Stroke SA, a community-based stroke support group in SA.  In the past he has coordinated annual media campaigns for the local community to raise awareness of Stroke prevention, treatment and research during National Stroke Week, which has gained local and national TV, radio, internet and print media coverage.

Prof Koblar has supervised 27 PhD, 3 Masters and 31 Honours students (27 received first class honours).  He has mentored many to positions of leadership, including A/Prof Jannes, a past PhD student, now Head of Neurology, CALHN; and A/Prof Hamilton-Bruce, Co-Director of the SRP.  He is currently Chair for the Adelaide Medical School Student Research Committee to encourage medical students to pursue research in their clinical course and beyond.

Education/Academic qualification

Graduate Certificate

PhD, Walter and Eliza Hall Institute of Medical Research

Fellowship of the Royal Australasian College of Physicians

BMBS, Flinders University

External positions

University of Adelaide


  • Stroke
  • Neurology
  • Neuroplasticity
  • Dental Pulp Stem Cells
  • Brain Repair
  • Adult Stem Cells
  • TIA - Transient Ischaemic Attack
  • Stroke Genetics

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Research Output

Are patient educational resources effective at deterring stroke survivors from considering experimental stem cell treatments? A randomized controlled trial

Unsworth, D. J., Mathias, J. L., Dorstyn, D. S. & Koblar, S. A., Jul 2020, In : Patient Education and Counseling. 103, 7, p. 1373-1381 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Developing a multivariable prediction model for functional outcome after reperfusion therapy for acute ischaemic stroke: study protocol for the Targeting Optimal Thrombolysis Outcomes (TOTO) multicentre cohort study

Holliday, E., Lillicrap, T., Kleinig, T., Choi, P. M. C., Maguire, J., Bivard, A., Lincz, L. F., Hamilton-Bruce, M. A., Rao, S. R., Snel, M. F., Trim, P. J., Lin, L., Parsons, M. W., Worrall, B. B., Koblar, S., Attia, J. & Levi, C., 6 Apr 2020, In : BMJ Open. 10, 4, p. e038180 038180.

Research output: Contribution to journalArticle

Prediction of general medical admission length of stay with natural language processing and deep learning: a pilot study

Bacchi, S., Gluck, S., Tan, Y., Chim, I., Cheng, J., Gilbert, T., Menon, D. K., Jannes, J., Kleinig, T. & Koblar, S., 1 Sep 2020, In : Internal and Emergency Medicine. 15, 6, p. 989-995 7 p.

Research output: Contribution to journalArticle

Two-year efficacy of varenicline tartrate and counselling for inpatient smoking cessation (STOP study): A randomized controlled clinical trial

Carson-Chahhoud, K. V., Smith, B. J., Peters, M. J., Brinn, M. P., Ameer, F., Singh, K., Fitridge, R., Koblar, S. A., Jannes, J., Veale, A. J., Goldsworthy, S., Hnin, K. & Esterman, A. J., Apr 2020, In : PloS one. 15, 4, e0231095.

Research output: Contribution to journalArticle

Economic Evaluation of Stem Cell Therapies in Neurological Diseases: A Systematic Review

Nagpal, A., Milte, R., Kim, S. W., Hillier, S., Hamilton-Bruce, M. A., Ratcliffe, J. & Koblar, S. A., Feb 2019, In : Value in Health. 22, 2, p. 254-262 9 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)