Research output per year
Research output per year
Personal profile
Research Interests
- Neurotrauma
- Neuropharmacology
- Molecular Biology
- Glia
- Oxidative stress
- Calcium dynamics
- Nuclear Imaging
- MRI
Public Profile
Ryan’s early research career has focused on understanding the pathophysiology of secondary degeneration following neurotrauma to the central nervous system (CNS). He uses innovative analytical techniques to demonstrate biochemical, molecular and gross anatomical changes that occur following CNS injury. Ryan has developed and optimised a combinatorial treatment strategy incorporating pharmacotherapeutics for the treatment of CNS injury. Ryan’s combinatorial strategy has been assessed in a clinically relevant model of spinal cord injury (SCI), demonstrating significant functional recovery and tissue sparing, crucial for the translation of his research into clinical trials.
In 2017, Ryan joined the SAHMRI Mind & Brain team in collaboration with Project Discovery and the Neil Sachse Centre for Spinal Cord Research, to provide his expertise in SCI and other neurotrauma models. Ryan looks to help develop new techniques to provide a more accurate diagnosis and prognosis of SCI, to identify potential treatment strategies in a clinical setting.
Education/Academic qualification
Bachelor's Degree, University of Western Australia
Bachelor's Degree (Honours), University of Western Australia
PhD, University of Western Australia
External positions
Adjunct Lecturer, University of Adelaide
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Biodegradable and biocompatible graphene-based scaffolds for functional neural tissue engineering: a strategy approach using dental pulp stem cells and biomaterials.
Mansouri, N., Al-Sarawi, S., Losic, D., Mazumdar, J., Clark, J., Gronthos, S. & O'Hare Doig, R., 15 Jul 2021, In: Biotechnology and Bioengineering.Research output: Contribution to journal › Article › peer-review
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Acute cellular and functional changes with a combinatorial treatment of ion channel inhibitors following spinal cord injury
O'Hare Doig, R. L., Santhakumar, S., Fehily, B., Raja, S., Solomon, T., Bartlett, C. A., Fitzgerald, M. & Hodgetts, S. I., 2020, In: Frontiers in molecular neuroscience. 13, p. 85Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
18-kDa translocator protein radioligand [18F]GE-180 as a diagnostic and prognostic biomarker following spinal cord injury
O'Hare Doig, R., Lewis, M., Keller, M., Clark, J., Jones, C. & Freeman, B. J. C., 2018.Research output: Contribution to conference › Poster › peer-review
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Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma
O'Hare Doig, R. L., Chiha, W., Giacci, M. K., Yates, N. J., Bartlett, C. A., Smith, N. M., Hodgetts, S. I., Harvey, A. R. & Fitzgerald, M., 14 Aug 2017, In: BMC Neuroscience. 18, 1, 62.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Specific combinations of ion channel inhibitors reduce excessive Ca2+ influx as a consequence of oxidative stress and increase neuronal and glial cell viability in vitro
O'Hare Doig, R. L., Bartlett, C. A., Smith, N. M., Hodgetts, S. I., Dunlop, S. A., Hool, L. & Fitzgerald, M., 17 Dec 2016, In: Neuroscience. 339, p. 450-462 13 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus)
Prizes
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Australian Postgraduate Award (Scholarship)
O'Hare Doig, Ryan (Recipient), 2013
Prize: Other distinction
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Activities
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Australian Society of Molecular Imaging Symposium
Johan Verjans (Organiser), Sally E. Plush (Organiser), Ryan O'Hare Doig (Organiser), Patrick Hughes (Organiser), Nicole Dmochowska (Organiser) & Marianne Keller (Organiser)
7 Nov 2019 → 8 Nov 2019Activity: Participating in or organising an event › Organising a conference
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South Australian Health & Medical Research Institute Animal Ethics Committee (External organisation)
Ryan O'Hare Doig (Chair)
2018 → …Activity: Membership › Membership of committee
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Molecular and Cellular Neuroscience (Journal)
Ryan O'Hare Doig (Reviewer)
2018 → 2019Activity: Publication peer-review and formal editorial roles › Publication peer-review
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International Journal of Peptide Research and Therapeutics (Journal)
Ryan O'Hare Doig (Reviewer)
2018 → 2019Activity: Publication peer-review and formal editorial roles › Publication peer-review
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Translational Neuroscience (Journal)
Ryan O'Hare Doig (Reviewer)
2018 → 2019Activity: Publication peer-review and formal editorial roles › Publication peer-review