• 66998 Citations
  • 130 h-Index
1974 …2020

Research output per year

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Personal profile

Public Profile

I am a UBC Killam Professor of Microbiology & Immunology, a Senior Research Fellow at SAHMRI South Australia, and a Canada Research Chair in Health and Genomics. My research interests include small cationic peptides as novel antimicrobials and modulators of innate immunity, the development of novel treatments for antibiotic resistant infections, the systems biology of innate immunity, inflammatory diseases and Pseudomonas aeruginosa, and antibiotic uptake and resistance. I have won several awards including the ICAAC Aventis Antimicrobial Research Award, the leading award for research on antimicrobials, and Canada’s three top prizes for Health Research, and I am an Officer of the Order of Canada. I am a co-founder of Migenix, Inimex Pharmaceuticals, ABT Innovations, Sepset Biotherapeutics, and the Centre for Drug Research and Development.

Research Interests

Education/Academic qualification

Bachelor of Science (Honours), University of Adelaide

… → 1971

PhD, University of Adelaide

… → 1975

External positions

Professor, University of British Columbia

Jul 1978 → …

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Research Output

AB569, a nontoxic chemical tandem that kills major human pathogenic bacteria

McDaniel, C. T., Panmanee, W., Winsor, G. L., Gill, E., Bertelli, C., Schurr, M. J., Dongare, P., Paul, A. T., Ko, S. H. B., Lau, G. W., Dasgupta, N., Bogue, A. L., Miller, W. E., Mortensen, J. E., Haslam, D. B., Dexheimer, P., Muruve, D. A., Aronow, B. J., Forbes, M. D. E., Danilczuk, M. & 4 others, Brinkman, F. S. L., Hancock, R. E. W., Meyer, T. J. & Hassett, D. J., 3 Mar 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 9, p. 4921-4930 10 p.

Research output: Contribution to journalArticle

Bacterial Aggregation Triggered by Fibril Forming Tryptophan-Rich Sequences: Effects of Peptide Side Chain and Membrane Phospholipids

Bagheri, M., Nikolenko, H., Arasteh, S., Rezaei, N., Behzadi, M., Dathe, M. & Hancock, R. E. W., 17 Jun 2020, In : ACS applied materials & interfaces. 12, 24, p. 26852-26867 16 p.

Research output: Contribution to journalArticle

EcDBS1R6: A novel cationic antimicrobial peptide derived from a signal peptide sequence

Porto, W. F., Irazazabal, L. N., Humblot, V., Haney, E. F., Ribeiro, S. M., Hancock, R. E. W., Ladram, A. & Franco, O. L., Sep 2020, In : Biochimica et Biophysica Acta - General Subjects. 1864, 9, 129633.

Research output: Contribution to journalArticle

Insights into the mechanism of action of two analogues of aurein 2.2

Raheem, N., Kumar, P., Lee, E., Cheng, J. T. J., Hancock, R. E. W. & Straus, S. K., 1 Jun 2020, In : Biochimica et Biophysica Acta - Biomembranes. 1862, 6, 183262.

Research output: Contribution to journalArticle

2 Citations (Scopus)

In vitro and in vivo antibiotic capacity of two host defense peptides

Arenas, I., Ibarra, M. A., Santana, F. L., Villegas, E., Hancock, R. E. W. & Corzo, G., Jul 2020, In : Antimicrobial Agents and Chemotherapy. 64, 7, e00145-20.

Research output: Contribution to journalArticle

1 Citation (Scopus)