Richard Young

Associate Professor, BSc (Hons), PhD, Director, Intestinal Nutrient Sensing Group

  • 2241 Citations
  • 27 h-Index
1993 …2020

Research output per year

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Personal profile

Public Profile

Richard L Young is an Associate Professor and Postgraduate and Honours Course Coordinator in the Adelaide Medical School at The University of Adelaide, and a Senior Research Fellow at the South Australian Health & Medical Research Institute (SAHMRI). He is a member of the Centre of Research Excellence in Translating Nutritional Science to Good Health (NHMRC 2013-2020) - an exceptional framework for linking basic and clinical researchers in Endocrinology and Gastroenterology.

He leads the Intestinal Nutrient Sensing Group within the Nutrition, Diabetes and Gut Health program of SAHMRI Lifelong Health in investigations focussed on the intestinal sweet taste system with clinicians, basic scientists and industry. This system detects dietary sugars and low-calorie sweeteners and can, in turn, regulate the uptake and disposal of glucose in the body. He has shown how this system is regulated in healthy individuals and the consequences of its dysregulation in type 2 diabetes, critical illness and obesity. His laboratory research focuses on the vertical integration of signals from intestinal sweet taste receptors and gut bacteria to the whole body, and has the potential to yield new ways to prevent, and better manage, type 2 diabetes.

A/Prof Young also leads research in an ARC and industry collaboration investigating other gut hormone systems in humans. This research has the potential to usher in novel therapies for obesity and type 2 diabetes.

Education/Academic qualification

PhD, University of Melbourne

Bachelor of Science (Honours), The University of Adelaide

External positions

University of Adelaide

Keywords

  • low calorie sweeteners
  • sweet taste receptors
  • type 2 diabetes
  • nutrient sensing
  • nutrient absorption
  • gut hormones
  • intestinal microbiota

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Research Output

Development of innovative tools for investigation of nutrient-gut interaction

Huang, W-K., Xie, C., Young, R. L., Zhao, J-B., Ebendorff-Heidepriem, H., Jones, K. L., Rayner, C. K. & Wu, T-Z., 7 Jul 2020, In : World Journal of Gastroenterology. 26, 25, p. 3562-3576 15 p.

Research output: Contribution to journalReview article

Nutrient-sensing components of the mouse stomach and the gastric ghrelin cell

Nunez-Salces, M., Li, H., Feinle-Bisset, C., Young, R. L. & Page, A. J., 14 Jul 2020, In : Neurogastroenterology and Motility. p. e13944

Research output: Contribution to journalArticle

1 Citation (Scopus)

Comparative effects of proximal and distal small intestinal glucose exposure on glycemia, incretin hormone secretion, and the incretin effect in health and type 2 diabetes

Zhang, X., Young, R., Bound, M., Hu, S., Jones, K. L., Horowitz, M., Rayner, C. K. & Wu, T., 1 Apr 2019, In : Diabetes Care. 42, 4, p. 520-528 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Low-calorie sweeteners augment tissue-specific insulin sensitivity in a large animal model of obesity

Malbert, C. H., Horowitz, M. & Young, R. L., 1 Oct 2019, In : European Journal of Nuclear Medicine and Molecular Imaging. 46, 11, p. 2380-2391 12 p.

Research output: Contribution to journalArticle

Metformin Triggers PYY Secretion in Human Gut Mucosa

Sun, E. W., Martin, A. M., Wattchow, D. A., de Fontgalland, D., Rabbitt, P., Hollington, P., Young, R. & Keating, D. J., 12 Feb 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 7, p. 2668-2674 7 p., jcem_201802460.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Prizes

Millennium Award in Type 2 Diabetes

Richard Young (Recipient), 2018

Prize: Honorary award