• 1285 Citations
  • 19 h-Index
19982019
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Research Output 1998 2019

  • 1285 Citations
  • 19 h-Index
  • 27 Article
  • 1 Comment/debate
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Article
2019

Sugar responses of human enterochromaffin cells depend on gut region, sex, and body mass

Lumsden, A. L., Martin, A. M., Sun, E. W., Schober, G., Isaacs, N. J., Pezos, N., Wattchow, D. A., de Fontgalland, D., Rabbitt, P., Hollington, P., Sposato, L., Due, S. L., Rayner, C. K., Nguyen, N. Q., Liou, A. P., Jackson, V. M., Young, R. L. & Keating, D. J., 1 Feb 2019, In : Nutrients. 11, 2, 234.

Research output: Contribution to journalArticle

2018
9 Citations (Scopus)

Augmented capacity for peripheral serotonin release in human obesity

Young, R., Lumsden, A. L., Martin, A. M., Schober, G., Pezos, N., Thazhath, S. S., Isaacs, N., Cvijanovic, N., Sun, E. W. L., Wu, T., Rayner, C. K., Nguyen, N. Q., Fontgalland, D. D., Rabbitt, P., Hollington, P., Sposato, L., Due, S. L., Wattchow, D. A., Liou, A. P., Jackson, V. M. & 1 othersKeating, D. J., 1 Nov 2018, In : International Journal of Obesity. 42, 11, p. 1880-1889 10 p.

Research output: Contribution to journalArticle

2017
11 Citations (Scopus)

Duodenal fatty acid sensor and transporter expression following acute fat exposure in healthy lean humans

Cvijanovic, N., Isaacs, N., Rayner, C. K., Feinle-Bisset, C., Young, R. & Little, T. J., 1 Apr 2017, In : Clinical Nutrition. 36, 2, p. 564-569 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Lipid stimulation of fatty acid sensors in the human duodenum: Relationship with gastrointestinal hormones, BMI and diet

Cvijanovic, N., Isaacs, N., Rayner, C. K., Feinle-Bisset, C., Young, R. & Little, T. J., 1 Feb 2017, In : International Journal of Obesity. 41, 2, p. 233-239 7 p.

Research output: Contribution to journalArticle

2014
25 Citations (Scopus)

Characterization of duodenal expression and localization of fatty acid-sensing receptors in humans: Relationships with body mass index

Little, T. J., Isaacs, N., Young, R., Ott, R., Nguyen, N. Q., Rayner, C. K., Horowitz, M. & Feinle-Bisset, C., 1 Jan 2014, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 307, 10, p. G958-G967

Research output: Contribution to journalArticle

2013
58 Citations (Scopus)

Disordered control of intestinal sweet taste receptor expression and glucose absorption in type 2 diabetes

Young, R., Chia, B., Isaacs, N., Ma, J., Khoo, J., Wu, T., Horowitz, M. & Rayner, C. K., 1 Oct 2013, In : Diabetes. 62, 10, p. 3532-3541 10 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Gastric vagal afferent modulation by leptin is influenced by food intake status

Kentish, S. J., O'Donnell, T. A., Isaacs, N. J., Young, R. L., Li, H., Harrington, A. M., Brierley, S. M., Wittert, G. A., Blackshaw, L. A. & Page, A. J., 1 Apr 2013, In : Journal of Physiology. 591, 7, p. 1921-1934 14 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
15 Citations (Scopus)

Modulation of murine gastric vagal afferent mechanosensitivity by neuropeptide W

Li, H., Kentish, S. J., Kritas, S., Young, R. L., Isaacs, N. J., O'Donnell, T. A., Blackshaw, L. A., Wittert, G. A. & Page, A. J., 1 Oct 2013, In : Acta Physiologica. 209, 2, p. 179-191 13 p.

Research output: Contribution to journalArticle

114 Citations (Scopus)

Sensory neuro-immune interactions differ between Irritable Bowel Syndrome subtypes

Hughes, P. A., Harrington, A. M., Castro, J., Liebregts, T., Adam, B., Grasby, D. J., Isaacs, N. J., Maldeniya, L., Martin, C. M., Persson, J., Andrews, J. M., Holtmann, G., Ashley Blackshaw, L. & Brierley, S. M., 1 Oct 2013, In : Gut. 62, 10, p. 1456-1465 10 p.

Research output: Contribution to journalArticle

2012
66 Citations (Scopus)

Diet-induced adaptation of vagal afferent function

Kentish, S., Li, H., Philp, L. K., O'Donnell, T. A., Isaacs, N. J., Young, R. L., Wittert, G. A., Blackshaw, L. A. & Page, A. J., 1 Jan 2012, In : Journal of Physiology. 590, 1, p. 209-221 13 p.

Research output: Contribution to journalArticle

2011
85 Citations (Scopus)

A novel role for TRPM8 in visceral afferent function

Harrington, A. M., Hughes, P. A., Martin, C. M., Yang, J., Castro, J., Isaacs, N. J., Ashley Blackshaw, L. & Brierley, S. M., 1 Jul 2011, In : Pain. 152, 7, p. 1459-1468 10 p.

Research output: Contribution to journalArticle

2010
35 Citations (Scopus)

Sensory and Motor Innervation of the Crural Diaphragm by the Vagus Nerves

Young, R. L., Page, A. J., Cooper, N. J., Frisby, C. L. & Blackshaw, L. A., 2010, In : Gastroenterology. 138, 3

Research output: Contribution to journalArticle

2009
26 Citations (Scopus)

Nitric oxide as an endogenous peripheral modulator of visceral sensory neuronal function

Page, A. J., O'Donnell, T. A., Cooper, N. J., Young, R. L. & Blackshaw, L. A., 3 Jun 2009, In : Journal of Neuroscience. 29, 22, p. 7245-7255 11 p.

Research output: Contribution to journalArticle

180 Citations (Scopus)

The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli

Brierley, S. M., Hughes, P. A., Page, A. J., Kwan, K. Y., Martin, C. M., O'Donnell, T. A., Cooper, N. J., Harrington, A. M., Adam, B., Liebregts, T., Holtmann, G., Corey, D. P., Rychkov, G. Y. & Blackshaw, L. A., 1 Jan 2009, In : Gastroenterology. 137, 6

Research output: Contribution to journalArticle

2008
21 Citations (Scopus)

Anatomy and function of group III metabotropic glutamate receptors in gastric vagal pathways

Young, R., Isaacs, N. & Ashley Blackshaw, L., 1 May 2008, In : Neuropharmacology. 54, 6, p. 965-975 11 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Chemical coding and central projections of gastric vagal afferent neurons

Young, R., Isaacs, N. & Blackshaw, L. A., 1 Jun 2008, In : Neurogastroenterology and Motility. 20, 6, p. 708-718 11 p.

Research output: Contribution to journalArticle

177 Citations (Scopus)

Selective Role for TRPV4 Ion Channels in Visceral Sensory Pathways

Brierley, S. M., Page, A. J., Hughes, P. A., Adam, B., Liebregts, T., Cooper, N. J., Holtmann, G., Liedtke, W. & Blackshaw, L. A., 1 Jan 2008, In : Gastroenterology. 134, 7, p. 2059-2069 11 p.

Research output: Contribution to journalArticle

101 Citations (Scopus)

Phenotypic characterization of taste cells of the mouse small intestine

Sutherland, K., Young, R., Isaacs, N., Horowitz, M. & Blackshaw, L. A., 1 May 2007, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 292, 5

Research output: Contribution to journalArticle

2005
79 Citations (Scopus)

Metabotropic glutamate receptors inhibit mechanosensitivity in vagal sensory neurons

Page, A. J., Young, R. L., Martin, C. M., Umaerus, M., O'Donnell, T. A., Cooper, N. J., Coldwell, J. R., Hulander, M., Mattsson, J. P., Lehmann, A. & Blackshaw, L. A., 2005, In : Gastroenterology. 128, 2, p. 402-410 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Modulation of gastro-oesophageal vagal afferents by galanin in mouse and ferret

Page, A. J., Slattery, J. A., O'Donnell, T. A., Cooper, N. J., Young, R. L. & Blackshaw, L. A., 15 Mar 2005, In : Journal of Physiology. 563, 3, p. 809-819 11 p.

Research output: Contribution to journalArticle

2001
56 Citations (Scopus)
8 Citations (Scopus)

Glycoconjugates on the surface of epididymal spermatozoa in a marsupial, the brushtail pos̊sum, Trichosurus vulpecula

Isaacs, N., McClean, R. V., Leigh, C. M. & Breed, W. G., 1 Jan 2001, In : Reproduction. 122, 1, p. 165-176 12 p.

Research output: Contribution to journalArticle

1998
4 Citations (Scopus)

Extratesticular sperm maturation in the brush-tail possum, Trichosurus vulpecula.

Isaacs, N., Holland, M. K. & Breed, W. G., 1998, In : Journal of reproduction and fertility. Supplement. 53, p. 221-226 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Protein synthesis and secretion by the epididymis of the brushtail possum, Trichosurus vulpecula

Lament, A. E., Clarke, H., Isaacs, N., Holland, M. K. & Breed, W. G., 5 Dec 1998, In : Journal of Reproduction and Fertility. 114, 1, p. 169-177 9 p.

Research output: Contribution to journalArticle