• 365 Citations
  • 10 h-Index

Research output per year

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Personal profile

Public Profile

Dr Grundy is an emerging leader in the field of Neurourology, having established an internationally recognised research program identifying the functional classes of afferents that innervate the bladder, and the channels and receptors underlying their function in health and chronic pain states. His research focuses on understanding the mechanisms that regulate sensory neurons that provide sensations from the bladder and the bacteria that cause urinary tract infections. Dr Grundy has a proven track record, with high impact publications in journals such as Nature, Pain, JCI insight, Scientific Reports, and the American Journal of Physiology. He also has invited reviews published in Annual Reviews of Physiology, American Journal of Phsyiology, and Frontiers in Autonomic Neuroscience.

Education/Academic qualification

PhD, Bond University

Bachelor of Science (Honours), University of Nottingham

External positions

Research Fellow, Flinders University College of Medicine and Public Health, Adelaide, SA, Australia.

Aug 2019 → …


  • Bladder
  • Colon
  • Pelvic Pain
  • Visceral Pain
  • Urinary Tract Infection
  • Chronic pain
  • Electrophysiology
  • Sensation

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Research Output

  • 365 Citations
  • 10 h-Index
  • 29 Article
  • 5 Review article
  • 2 Chapter

A spider-venom peptide with multi-target activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome

Cardoso, F. C., Castro, J., Grundy, L., Schober, G., Garcia-Caraballo, S., Zhao, T., Herzig, V., King, G. F., Brierley, S. M. & Lewis, R. J., 17 Aug 2020, In : Pain.

Research output: Contribution to journalArticle

Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H1 receptor and TRPV1

Grundy, L., Caldwell, A., Garcia Caraballo, S., Erickson, A., Schober, G., Castro Kraftchenko, J., Harrington, A. & Brierley, S. M., 1 Feb 2020, In : American journal of physiology. Renal physiology. 318, 2, p. F298-F314

Research output: Contribution to journalArticle

Innate immune response to bacterial urinary tract infection sensitises high-threshold bladder afferents and recruits silent nociceptors

Brierley, S., Goh, K. G. K., Sullivan, M. J., Moore, K. H., Ulett, G. C. & Grundy, L., 1 Jan 2020, In : Pain. 161, 1, p. 202-210 9 p.

Research output: Contribution to journalArticle