Louise O'Keefe


  • 1694 Citations
  • 17 h-Index
1993 …2019

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Public Profile

Louise O’Keefe obtained her PhD studying cytokinesis in Drosophila and was subsequently awarded an NHRMC Peter Doherty Post-Doctoral training Fellowship to develop Drosophila as a genetic system to understand complex human diseases. She currently holds a joint position as Research Fellow in the Department of Molecular and Biomedical Science at the University of Adelaide as well as Research Officer at SAHMRI with a focus on using Drosophila to determine the cellular pathways and processes contributing to late onset neurodegenerative diseases as well as MPS type III childhood dementia.

Education/Academic qualification

PhD, University of Adelaide

External positions

University Research Fellow, University of Adelaide

1 Jan 2002 → …

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output

  • 1694 Citations
  • 17 h-Index
  • 26 Article
  • 3 Review article
  • 2 Comment/debate

Non-self mutation: Double-stranded RNA elicits antiviral pathogenic response in a Drosophila model of expanded CAG repeat neurodegenerative diseases

van Eyk, C. L., Samaraweera, S. E., Scott, A., Webber, D. L., Harvey, D. P., Mecinger, O., O'Keefe, L., Cropley, J. E., Young, P., Ho, J., Suter, C. & Richards, R. I., 1 Sep 2019, In : Human Molecular Genetics. 28, 18, p. 3000-3012 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan

Xie, J., de Souza Alves, V., von der Haar, T., O'Keefe, L., Lenchine, R. V., Jensen, K. B., Liu, R., Coldwell, M. J., Wang, X. & Proud, C. G., 4 Feb 2019, In : Current Biology. 29, 5

Research output: Contribution to journalArticle

4 Citations (Scopus)

CRISPR/Cas9-mediated mutagenesis of the white gene in the tephritid pest Bactrocera tryoni

Choo, A., Crisp, P., Saint, R., O'Keefe, L. V. & Baxter, S. W., 1 Feb 2018, In : Journal of Applied Entomology. 142, 1-2, p. 52-58 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Using Models of Amyloid Toxicity to Study Autophagy in the Pathogenesis of Alzheimer's Disease

O'Keefe, L. & Denton, D., 2018, In : BioMed Research International. 2018, p. 5195416

Research output: Contribution to journalReview article

4 Citations (Scopus)

The Enemy within: Innate Surveillance-Mediated Cell Death, the Common Mechanism of Neurodegenerative Disease

Richards, R. I., Robertson, S. A., O'Keefe, L. V., Fornarino, D., Scott, A., Lardelli, M. & Baune, B. T., 2016, In : Frontiers in Neuroscience. 10, p. 193

Research output: Contribution to journalArticle

20 Citations (Scopus)