Laura Eadie

Dr, BSc (Biomed), Hons, PhD

  • Source: Scopus
  • Calculated based on no. of publications stored in Pure and citations from Scopus
20082020

Research output per year

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Personal profile

Public Profile

Dr Eadie is an award-winning biomedical researcher and the current Peter Nelson Leukaemia Research Fellow (2019-2021). She is a previous Fulbright scholar, a TEDx speaker and science communicator.

Laura has been awarded three project grants: one as Chief Investigator A, one as Chief Investigator B and one as Associate Investigator. Since commencing her PhD, for which she received a Dean’s Commendation, Laura has received nine fellowships/scholarships. She is a previous recipient of a prestigious Australian-American Fulbright award which allowed her to develop her research strategy overseas at one of the leading research hospitals in the world. She has won ten additional prizes and awards including travel grants to present her research at national and international meetings and was a Top 10 Fresh Scientist SA (2017) awarded by Science in Public for excellence in science communication.

Public Profile

Research Focus 

Acute Lymphoblastic Leukaemia (ALL) is an extremely heterogeneous disease with subtypes of patients exhibiting a diverse range of genetic mutations. Certain subtypes of ALL can be treated with drugs already in clinical use. Laura undertook her Fulbright fellowship (2016-2017) at St. Jude Children’s Research Hospital in Memphis, Tennessee where she learned mouse models of high-risk ALL. Laura is now leading in vivo mouse studies for high-risk ALL with a specific focus on T-cell ALL. Her research will assess targeted therapies in mouse models of ALL through ongoing generation of 1) patient derived xenografts from patient samples received in our laboratory and 2) transgenic models. This will enable the evaluation of novel and combination therapeutic approaches compared with the current standard of care. Mouse models of drug resistance will also be developed and pre-emptive intervention in the resistant disease setting investigated. These studies will ultimately inform clinical practice, impacting significantly on response to therapy and overall survival of adults and children with high-risk ALL. 

Education/Academic qualification

PhD, University of Adelaide

30 Mar 200927 Mar 2013

Bachelor's Degree (Honours), University of Adelaide

17 Jan 20062 Dec 2006

Bachelor's Degree, University of Adelaide

22 Jan 20032 Dec 2005

External positions

Affiliate Senior Lecturer Discipline of Medicine, University of Adelaide

Apr 2020 → …

Post Doctoral Research Associate, St. Jude Children's Research Hospital

14 Aug 201615 Aug 2017

Affiliate Lecturer Discipline of Medicine, University of Adelaide

Apr 2014Apr 2020

Keywords

  • acute lymphoblastic leukaemia
  • mouse models
  • next generation sequencing
  • drug resistance
  • leukaemia

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