Karen Best


  • 405 Citations
  • 5 h-Index
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Personal profile

Public Profile

Karen completed her Registered Nurse Certificate at The Queen Elizabeth Hospital in Adelaide and then went on to complete her Registered Midwifery Certificate at the Queen Victoria Hospital. 

Following completion of a Graduate Midwife Program, she spent a number of years working in the Neonatal Unit at the Women’s & Children’s Hospital (WCH) caring for premature babies and their families before becoming interested in research.

Following a role as a Clinical Studies Nurse in a Phase I – IV clinical trial facility in Adelaide, she joined Professor Maria Makrides at the Child Nutrition Research Centre (CNRC), at the WCH in 2003. 

Karen completed a Graduate Certificate in Clinical Trial Management through Canberra University and managed a number of large, national multicentre trials with Professor Makrides. To expand her knowledge, she undertook a role of Clinical Trial Project Manager of a large pharmaceutical company sponsored clinical trial of blood pressure management in Primary Care at the Baker IDI Heart and Diabetes Institute, Adelaide. 

Whilst learning a great deal in this role, Karen missed maternal and child health and returned to the CNRC to commence her PhD under the supervision of Professor Makrides. Karen was awarded the MS McLeod Paediatric and Child Health Nursing PhD Scholarship in 2012 for her project investigating the effect of prenatal omega-3 supplementation on allergy in the offspring at 6 years of age. Following completion of more than 600 childhood allergy assessments, she completed her PhD in 2015 with a Dean’s commendation for post-doctoral thesis excellence. 

Karen is currently working on the largest trial in the world (5500 women) to investigate the effect of prenatal omega-3 supplementation on the prevention of preterm birth and has a strong interest in maternal health and clinical trial design and management.

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Research Output 2000 2019

  • 405 Citations
  • 5 h-Index
  • 10 Article
  • 3 Other report
  • 1 Chapter
  • 1 Review article

A randomized trial of prenatal n−3 fatty acid supplementation and preterm delivery

Makrides, M., Best, K., Yelland, L., McPhee, A., Zhou, S., Quinlivan, J., Dodd, J., Atkinson, E., Safa, H., Van Dam, J., Khot, N., Dekker, G., Skubisz, M., Anderson, A., Kean, B., Bowman, A., McCallum, C., Cashman, K. & Gibson, R., 12 Sep 2019, In : New England Journal of Medicine. 381, 11, p. 1035-1045 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Docosahexaenoic acid supplementation of preterm infants and parent-reported symptoms of allergic disease at 7 years corrected age: Follow-up of a randomized controlled trial

Gunaratne, A. W., Makrides, M., Collins, C., Gibson, R., McPhee, A., Sullivan, T., Gould, J., Green, T., Doyle, L. W., Davis, P. G., French, N. P., Colditz, P. B., Simmer, K., Morris, S. A. & Best, K., 1 Jun 2019, In : American Journal of Clinical Nutrition. 109, 6, p. 1600-1610 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Perinatal nutrition interventions and post-partum depressive symptoms

Gould, J., Best, K. & Makrides, M., 15 Dec 2017, In : Journal of Affective Disorders. 224, p. 2-9 8 p.

Research output: Contribution to journalReview article

Polyunsaturated fatty acids: metabolism and nutritional requirements in pregnancy and infancy

Muhlhausler, B., Collins, C., Gould, J., Best, K. & Leghi, G., 2017, Polyunsaturated Fatty Acid Metabolism. Burdge, G. (ed.). San diego: Elsevier Inc., p. 111 134 p.

Research output: Chapter in Book/Report/Conference proceedingChapter