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Josephine Wright

Dr, BSc(Hons) PhD

  • 1847 Citations
  • 16 h-Index
20022020

Research output per year

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Personal profile

Public Profile

Dr Josephine Wright is a Senior Research Fellow in the Gut Health group. In collaboration with the Gut Cancer group, she has been developing a translational network of labs, hospitals and clinics to enable validation of new approaches to prevent and treat colorectal and gastric cancer. Her key focus is studying human tumour organoids to better personliase therapy in cancer.

Education/Academic qualification

Bachelor of Science (Honours), University of Adelaide

PhD, University of Adelaide

2000 → 2004

Keywords

  • organoids
  • colorectal cancer
  • gastric cancer

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Research Output

  • 1847 Citations
  • 16 h-Index
  • 19 Article
  • 2 Review article
  • 1 Short survey

Medium-throughput Drug Screening of Patient-derived Organoids from Colorectal Peritoneal Metastases to Direct Personalized Therapy

Narasimhan, V., Wright, J. A., Churchill, M., Wang, T., Rosati, R., Lannagan, T. R. M., Vrbanac, L., Richardson, A. B., Kobayashi, H., Price, T., Tye, G. X. Y., Marker, J., Hewett, P. J., Flood, M. P., Pereira, S., Whitney, G. A., Michael, M., Tie, J., Mukherjee, S., Grandori, C. & 4 others, Heriot, A. G., Worthley, D. L., Ramsay, R. G. & Woods, S. L., 6 May 2020, In : Clinical Cancer Research.

Research output: Contribution to journal › Article

Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis

Lannagan, T. R. M., Lee, Y. K., Wang, T., Roper, J., Bettington, M. L., Fennell, L., Vrbanac, L., Jonavicius, L., Somashekar, R., Gieniec, K., Yang, M., Ng, J. Q., Suzuki, N., Ichinose, M., Wright, J. A., Kobayashi, H., Putoczki, T. L., Hayakawa, Y., Leedham, S. J., Abud, H. E. & 10 others, Yilmaz, Ö. H., Marker, J., Klebe, S., Wirapati, P., Mukherjee, S., Tejpar, S., Leggett, B. A., Whitehall, V. L. J., Worthley, D. L. & Woods, S. L., 1 Apr 2019, In : Gut. 68, 4, p. 684-692 9 p.

Research output: Contribution to journal › Article

18 Citations (Scopus)

Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion

Bracken, C. P., Li, X., Wright, J. A., Lawrence, D. M., Pillman, K. A., Salmanidis, M., Anderson, M. A., Dredge, B. K., Gregory, P. A., Tsykin, A., Neilsen, C., Thomson, D. W., Bert, A. G., Leerberg, J. M., Yap, A. S., Jensen, K. B., Khew-Goodall, Y. & Goodall, G. J., 1 Jan 2014, In : EMBO Journal. 33, 18, p. 2040-2056 17 p.

Research output: Contribution to journal › Article

89 Citations (Scopus)

MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways

Li, X., Roslan, S., Johnstone, C. N., Wright, J., Bracken, C. P., Anderson, M., Bert, A. G., Selth, L. A., Anderson, R. L., Goodall, G. J., Gregory, P. A. & Khew-Goodall, Y., 31 Jul 2014, In : Oncogene. 33, 31, p. 4077-4088 12 p.

Research output: Contribution to journal › Article

85 Citations (Scopus)

Regulation of the neuronal transcription factor NPAS4 by REST and microRNAs

Bersten, D. C., Wright, J., McCarthy, P. J. & Whitelaw, M. L., 1 Jan 2014, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1839, 1, p. 13-24 12 p.

Research output: Contribution to journal › Article

17 Citations (Scopus)