• 900 Citations
  • 14 h-Index
20072020

Research output per year

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Personal profile

Research Interests

Research Focus 

As leader of the SAHMRI Bioinformatics Core, my group develops computational tools and workflows to enable researchers to analyse large genomics datasets, as well as working with SAHMRI research groups as a Bioinformatics consultant. Our group’s current research interests include developing methods for clinical cancer sequencing (in collaboration with the Leukaemia research group) and investigating epigenetic and structural gene regulation using multi-omic datasets, with a primary focus on reproductive systems such as the human placenta and early adaptive immune network. 

Education/Academic qualification

PhD, Murdoch University

Keywords

  • RG Gynecology and obstetrics
  • Reproductive Biology
  • QH426 Genetics
  • Genomics
  • RC0254 Neoplasms. Tumors. Oncology (including Cancer)
  • Cancer Biology
  • QA76 Computer software
  • Bioinformatics

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Research Output

  • 900 Citations
  • 14 h-Index
  • 38 Article
  • 4 Review article
  • 1 Comment/debate

Effects of aging on the motor, cognitive and affective behaviors, neuroimmune responses and hippocampal gene expression

Singhal, G., Morgan, J., Jawahar, M. C., Corrigan, F., Jaehne, E. J., Toben, C., Breen, J., Pederson, S. M., Manavis, J., Hannan, A. J. & Baune, B. T., 6 Apr 2020, In : Behavioural Brain Research. 383, 112501.

Research output: Contribution to journalArticle

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D

Kennedy, S. A., Jarboui, M-A., Srihari, S., Raso, C., Bryan, K., Dernayka, L., Charitou, T., Bernal-Llinares, M., Herrera-Montavez, C., Krstic, A., Matallanas, D., Kotlyar, M., Jurisica, I., Curak, J., Wong, V., Stagljar, I., LeBihan, T., Imrie, L., Pillai, P., Lynn, M. A. & 21 othersFasterius, E., Al-Khalili Szigyarto, C., Breen, J., Kiel, C., Serrano, L., Rauch, N., Rukhlenko, O., Kholodenko, B. N., Iglesias-Martinez, L. F., Ryan, C. J., Pilkington, R., Cammareri, P., Sansom, O., Shave, S., Auer, M., Horn, N., Klose, F., Ueffing, M., Boldt, K., Lynn, D. J. & Kolch, W., 24 Jan 2020, In : Nature communications. 11, 1, p. 499

Research output: Contribution to journalArticle

Autosomal dominant nanophthalmos and high hyperopia associated with a C-terminal frameshift variant in MYRF

Siggs, O. M., Souzeau, E., Breen, J., Qassim, A., Zhou, T., Dubowsky, A., Ruddle, J. B. & Craig, J. E., 1 Jan 2019, In : Molecular Vision. 25, p. 527-534 8 p.

Research output: Contribution to journalArticle

Ceasing exercise induces depression-like, anxiety-like, and impaired cognitive-like behaviours and altered hippocampal gene expression

Morgan, J. A., Singhal, G., Corrigan, F., Jaehne, E. J., Jawahar, M. C., Breen, J., Pederson, S. & Baune, B. T., 1 May 2019, In : Brain Research Bulletin. 148, p. 118-130 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Haemoglobin expression in in vivo murine preimplantation embryos suggests a role in oxygen-regulated gene expression

Lim, M., Brown, H. M., Kind, K. L., Breen, J., Anastasi, M. R., Ritter, L. J., Tregoweth, E. K., Dinh, D. T., Thompson, J. G. & Dunning, K. R., 1 Jan 2019, In : Reproduction, Fertility and Development. 31, 4, p. 724-734 11 p.

Research output: Contribution to journalArticle