• 1008 Citations
  • 15 h-Index
20072020

Research output per year

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Personal profile

Research Interests

Research Focus 

As leader of the SAHMRI Bioinformatics Core, my group develops computational tools and workflows to enable researchers to analyse large genomics datasets, as well as working with SAHMRI research groups as a Bioinformatics consultant. Our group’s current research interests include developing methods for clinical cancer sequencing (in collaboration with the Leukaemia research group) and investigating epigenetic and structural gene regulation using multi-omic datasets, with a primary focus on reproductive systems such as the human placenta and early adaptive immune network. 

Education/Academic qualification

PhD, Murdoch University

Keywords

  • Reproductive Biology
  • Genomics
  • Cancer Biology
  • Bioinformatics

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Research Output

  • 1008 Citations
  • 15 h-Index
  • 40 Article
  • 4 Review article
  • 1 Comment/debate
  • 1 Letter

Effects of aging on the motor, cognitive and affective behaviors, neuroimmune responses and hippocampal gene expression

Singhal, G., Morgan, J., Jawahar, M. C., Corrigan, F., Jaehne, E. J., Toben, C., Breen, J., Pederson, S. M., Manavis, J., Hannan, A. J. & Baune, B. T., 6 Apr 2020, In : Behavioural Brain Research. 383, 112501.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D

Kennedy, S. A., Jarboui, M-A., Srihari, S., Raso, C., Bryan, K., Dernayka, L., Charitou, T., Bernal-Llinares, M., Herrera-Montavez, C., Krstic, A., Matallanas, D., Kotlyar, M., Jurisica, I., Curak, J., Wong, V., Stagljar, I., LeBihan, T., Imrie, L., Pillai, P., Lynn, M. A. & 21 others, Fasterius, E., Al-Khalili Szigyarto, C., Breen, J., Kiel, C., Serrano, L., Rauch, N., Rukhlenko, O., Kholodenko, B. N., Iglesias-Martinez, L. F., Ryan, C. J., Pilkington, R., Cammareri, P., Sansom, O., Shave, S., Auer, M., Horn, N., Klose, F., Ueffing, M., Boldt, K., Lynn, D. J. & Kolch, W., 24 Jan 2020, In : Nature communications. 11, 1, p. 499

Research output: Contribution to journalArticle

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D

Kennedy, S. A., Jarboui, M. A., Srihari, S., Raso, C., Bryan, K., Dernayka, L., Charitou, T., Bernal-Llinares, M., Herrera-Montavez, C., Krstic, A., Matallanas, D., Kotlyar, M., Jurisica, I., Curak, J., Wong, V., Stagljar, I., LeBihan, T., Imrie, L., Pillai, P., Lynn, M. A. & 21 others, Fasterius, E., Al-Khalili Szigyarto, C., Breen, J., Kiel, C., Serrano, L., Rauch, N., Rukhlenko, O., Kholodenko, B. N., Iglesias-Martinez, L. F., Ryan, C. J., Pilkington, R., Cammareri, P., Sansom, O., Shave, S., Auer, M., Horn, N., Klose, F., Ueffing, M., Boldt, K., Lynn, D. J. & Kolch, W., 1 Dec 2020, In : Nature Communications. 11, 1, 499.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

High-risk B-cell acute lymphoblastic leukaemia presenting with hypereosinophilia and acquiring a novel PAX5 fusion on relapse

McClure, B. J., Heatley, S. L., Rehn, J., Breen, J., Sutton, R., Hughes, T. P., Suppiah, R., Revesz, T., Osborn, M., White, D., Yeung, D. T. & White, D. L., 1 Jan 2020, (Accepted/In press) In : British Journal of Haematology.

Research output: Contribution to journalLetter

Open Access

HOPX regulates bone marrow-derived mesenchymal stromal cell fate determination via suppression of adipogenic gene pathways

Hng, C. H., Camp, E., Anderson, P., Breen, J., Zannettino, A. & Gronthos, S., 1 Dec 2020, In : Scientific reports. 10, 1, 11345.

Research output: Contribution to journalArticle

Open Access