Research Output per year
Personal profile
Research Interests
Research Focus
As leader of the SAHMRI Bioinformatics Core, my group develops computational tools and workflows to enable researchers to analyse large genomics datasets, as well as working with SAHMRI research groups as a Bioinformatics consultant. Our group’s current research interests include developing methods for clinical cancer sequencing (in collaboration with the Leukaemia research group) and investigating epigenetic and structural gene regulation using multi-omic datasets, with a primary focus on reproductive systems such as the human placenta and early adaptive immune network.
Education/Academic qualification
PhD, Murdoch University
Keywords
- RG Gynecology and obstetrics
- Reproductive Biology
- QH426 Genetics
- Genomics
- RC0254 Neoplasms. Tumors. Oncology (including Cancer)
- Cancer Biology
- QA76 Computer software
- Bioinformatics
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output
Effects of aging on the motor, cognitive and affective behaviors, neuroimmune responses and hippocampal gene expression
Singhal, G., Morgan, J., Jawahar, M. C., Corrigan, F., Jaehne, E. J., Toben, C., Breen, J., Pederson, S. M., Manavis, J., Hannan, A. J. & Baune, B. T., 6 Apr 2020, In : Behavioural Brain Research. 383, 112501.Research output: Contribution to journal › Article
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Kennedy, S. A., Jarboui, M-A., Srihari, S., Raso, C., Bryan, K., Dernayka, L., Charitou, T., Bernal-Llinares, M., Herrera-Montavez, C., Krstic, A., Matallanas, D., Kotlyar, M., Jurisica, I., Curak, J., Wong, V., Stagljar, I., LeBihan, T., Imrie, L., Pillai, P., Lynn, M. A. & 21 others, 24 Jan 2020, In : Nature communications. 11, 1, p. 499Research output: Contribution to journal › Article
Autosomal dominant nanophthalmos and high hyperopia associated with a C-terminal frameshift variant in MYRF
Siggs, O. M., Souzeau, E., Breen, J., Qassim, A., Zhou, T., Dubowsky, A., Ruddle, J. B. & Craig, J. E., 1 Jan 2019, In : Molecular Vision. 25, p. 527-534 8 p.Research output: Contribution to journal › Article
Ceasing exercise induces depression-like, anxiety-like, and impaired cognitive-like behaviours and altered hippocampal gene expression
Morgan, J. A., Singhal, G., Corrigan, F., Jaehne, E. J., Jawahar, M. C., Breen, J., Pederson, S. & Baune, B. T., 1 May 2019, In : Brain Research Bulletin. 148, p. 118-130 13 p.Research output: Contribution to journal › Article
3
Citations
(Scopus)
Haemoglobin expression in in vivo murine preimplantation embryos suggests a role in oxygen-regulated gene expression
Lim, M., Brown, H. M., Kind, K. L., Breen, J., Anastasi, M. R., Ritter, L. J., Tregoweth, E. K., Dinh, D. T., Thompson, J. G. & Dunning, K. R., 1 Jan 2019, In : Reproduction, Fertility and Development. 31, 4, p. 724-734 11 p.Research output: Contribution to journal › Article