• 847 Citations
  • 14 h-Index
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Personal profile

Research Interests

Research Focus 

As leader of the SAHMRI Bioinformatics Core, my group develops computational tools and workflows to enable researchers to analyse large genomics datasets, as well as working with SAHMRI research groups as a Bioinformatics consultant. Our group’s current research interests include developing methods for clinical cancer sequencing (in collaboration with the Leukaemia research group) and investigating epigenetic and structural gene regulation using multi-omic datasets, with a primary focus on reproductive systems such as the human placenta and early adaptive immune network. 

Education/Academic qualification

PhD, Murdoch University


  • RG Gynecology and obstetrics
  • Reproductive Biology
  • QH426 Genetics
  • Genomics
  • RC0254 Neoplasms. Tumors. Oncology (including Cancer)
  • Cancer Biology
  • QA76 Computer software
  • Bioinformatics

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2007 2019

  • 847 Citations
  • 14 h-Index
  • 35 Article
  • 4 Review article
  • 1 Comment/debate

Autosomal dominant nanophthalmos and high hyperopia associated with a C-terminal frameshift variant in MYRF

Siggs, O. M., Souzeau, E., Breen, J., Qassim, A., Zhou, T., Dubowsky, A., Ruddle, J. B. & Craig, J. E., 1 Jan 2019, In : Molecular Vision. 25, p. 527-534 8 p.

Research output: Contribution to journalArticle

Ceasing exercise induces depression-like, anxiety-like, and impaired cognitive-like behaviours and altered hippocampal gene expression

Morgan, J. A., Singhal, G., Corrigan, F., Jaehne, E. J., Jawahar, M. C., Breen, J., Pederson, S. & Baune, B. T., 1 May 2019, In : Brain Research Bulletin. 148, p. 118-130 13 p.

Research output: Contribution to journalArticle

Haemoglobin expression in in vivo murine preimplantation embryos suggests a role in oxygen-regulated gene expression

Lim, M., Brown, H. M., Kind, K. L., Breen, J., Anastasi, M. R., Ritter, L. J., Tregoweth, E. K., Dinh, D. T., Thompson, J. G. & Dunning, K. R., 1 Jan 2019, In : Reproduction, Fertility and Development. 31, 4, p. 724-734 11 p.

Research output: Contribution to journalArticle

It takes a community to conceive: an analysis of the scope, nature and accuracy of online sources of health information for couples trying to conceive

Kedzior, S. G. E., Bianco-Miotto, T., Breen, J., Diener, K. R., Donnelley, M., Dunning, K. R., Penno, M. A. S., Schjenken, J. E., Sharkey, D. J., Hodyl, N. A., Fullston, T., Gardiner, M., Brown, H. M. & Rumbold, A. R., Oct 2019, In : Reproductive Biomedicine & Society Online.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Laboratory contamination over time during low-biomass sample analysis

Weyrich, L. S., Farrer, A. G., Eisenhofer, R., Arriola, L. A., Young, J., Selway, C. A., Handsley-Davis, M., Adler, C. J., Breen, J. & Cooper, A., 1 Jul 2019, In : Molecular Ecology Resources. 19, 4, p. 982-996 15 p.

Research output: Contribution to journalArticle