Georgina Eden

  • 24 Citations
  • 3 h-Index
20162019
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Personal profile

Public Profile

Georgina completed her Honours at The University of Adelaide working on developing novel therapies for the adverse side effects of chemotherapy on the gastrointestinal tract. She then worked at the Children’s Cancer Institute in Sydney for 4 years where she assisted in discovering new therapeutic approaches for the treatment of Neuroblastoma (most common extracranial solid tumour in children). During her time at the Children’s Cancer Institute she was involved in the Zero Childhood Cancer national clinical trial. This trial aims to develop personalised cancer treatment strategies for children, throughout Australia, with high-risk or relapsed cancer.

In mid-2018, Georgina returned to Adelaide to work as an EMBL Australia Research Officer in David Lynn’s Computational and Systems Biology Program, part of the Precision Medicine Theme at at SAHMRI. She is assisting in projects investigating the interplay between the microbiota and the immune system.

 

Publications

Murray J, +4, Eden GL, +14, Fletcher JI, Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma growth and sensitises to irinotecan in vivo, Eur J Cancer, 2017 Sep;83: 132-141

Bajic JE, Eden GL, Lampton LS, Cheah KY, Lymn KA, Pei JV, Yool AJ and Howarth GS, Rhubarb extract partially improves mucosal integrity in chemotherapy-induced mucositis, World J Gastroenterol, 2016 Oct 7; 22(37): 8322-8333

 Mashtoub S, Lampton LS, Eden GL, Cheah KY, Lymn KA, Bajic JE and Howarth GS, Emu oil combined with Lyprinol™ reduces small intestinal damage in a rat model of chemotherapy-induced mucositis, Nutr Cancer, 2016 Oct; 68(7);1171

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Research Output 2016 2019

  • 24 Citations
  • 3 h-Index
  • 5 Article
3 Citations (Scopus)

Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma

Gamble, L. D., Purgato, S., Murray, J., Xiao, L., Yu, D. M. T., Hanssen, K. M., Giorgi, F. M., Carter, D. R., Gifford, A. J., Valli, E., Milazzo, G., Kamili, A., Mayoh, C., Liu, B., Eden, G., Sarraf, S., Allan, S., Giacomo, S. D., Flemming, C. L., Russell, A. J. & 13 othersCheung, B. B., Oberthuer, A., London, W. B., Fischer, M., Trahair, T. N., Fletcher, J. I., Marshall, G. M., Ziegler, D. S., Hogarty, M. D., Burns, M. R., Perini, G., Norris, M. D. & Haber, M., 30 Jan 2019, In : Science Translational Medicine. 11, 477, aau1099.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Macrophage-derived IL1B and TNFa regulate arginine metabolism in neuroblastoma

Fultang, L., Gamble, L. D., Gneo, L., Berry, A. M., Egan, S. A., De Bie, F., Yogev, O., Eden, G., Booth, S., Brownhill, S., Vardon, A., McConville, C. M., Cheng, P. N., Norris, M. D., Etchevers, H. C., Murray, J., Ziegler, D. S., Chesler, L., Schmidt, R., Burchill, S. A. & 3 othersHaber, M., De Santo, C. & Mussai, F., 1 Jan 2019, In : Cancer Research. 79, 3, p. 611-624 14 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo

Murray, J., Valli, E., Yu, D. M. T., Truong, A. M., Gifford, A. J., Eden, G., Gamble, L. D., Hanssen, K. M., Flemming, C. L., Tan, A., Tivnan, A., Allan, S., Saletta, F., Cheung, L., Ruhle, M., Schuetz, J. D., Henderson, M. J., Byrne, J. A., Norris, M. D., Haber, M. & 1 othersFletcher, J. I., 1 Sep 2017, In : European Journal of Cancer. 83, p. 132-141 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Emu Oil Combined with Lyprinol™ Reduces Small Intestinal Damage in a Rat Model of Chemotherapy-Induced Mucositis

Mashtoub, S., Lampton, L. S., Eden, G., Cheah, K. Y., Lymn, K. A., Bajic, J. E. & Howarth, G. S., 2 Oct 2016, In : Nutrition and Cancer. 68, 7, p. 1171-1180 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Rhubarb extract partially improves mucosal integrity in chemotherapy-induced intestinal mucositis

Bajic, J. E., Eden, G., Lampton, L. S., Cheah, K. Y., Lymn, K. A., Pei, J. V., Yool, A. J. & Howarth, G. S., 7 Oct 2016, In : World Journal of Gastroenterology. 22, 37, p. 8322-8333 12 p.

Research output: Contribution to journalArticle