Christopher Proud

Professor

  • 20793 Citations
  • 82 h-Index
1975 …2020

Research output per year

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Research Output

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Review article
2018

Osteocalcin-dependent regulation of glucose metabolism and fertility: Skeletal implications for the development of insulin resistance

Tangseefa, P., Martin, S. K., Fitter, S., Baldock, P. A., Proud, C. G. & Zannettino, A. C. W., 1 May 2018, In : Journal of Cellular Physiology. 233, 5, p. 3769-3783 15 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Who does TORC2 talk to?

Xie, J., Wang, X. & Proud, C. G., 24 May 2018, In : Biochemical Journal. 475, 10, p. 1721-1738 18 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)
2017

Eukaryotic elongation factor 2 kinase (eEF2K) in cancer

Wang, X., Xie, J. & Proud, C., 1 Dec 2017, In : Cancers. 9, 12, 162.

Research output: Contribution to journalReview article

9 Citations (Scopus)
2016

Eukaryotic elongation factor 2 kinase as a drug target in cancer, and in cardiovascular and neurodegenerative diseases

Liu, R. & Proud, C., 1 Mar 2016, In : Acta Pharmacologica Sinica. 37, 3, p. 285-294 10 p.

Research output: Contribution to journalReview article

27 Citations (Scopus)

mTOR inhibitors in cancer therapy [version 1; referees: 3 approved]

Xie, J., Wang, X. & Proud, C. G., 1 Jan 2016, In : F1000Research. 5, 2078.

Research output: Contribution to journalReview article

58 Citations (Scopus)

Tuning Specific Translation in Cancer Metastasis and Synaptic Memory: Control at the MNK–eIF4E Axis

Bramham, C. R., Jensen, K. B. & Proud, C. G., 1 Oct 2016, In : Trends in Biochemical Sciences. 41, 10, p. 847-858 12 p.

Research output: Contribution to journalReview article

36 Citations (Scopus)
2015

Dissecting the signaling pathways that mediate cancer in PTEN and LKB1 double-knockout mice

Chen, J., Zhang, X. D. & Proud, C., 1 Jan 2015, In : Science Signaling. 8, 392, pe1.

Research output: Contribution to journalReview article

22 Citations (Scopus)

Mnks, eIF4E phosphorylation and cancer

Proud, C., 1 Jul 2015, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1849, 7, p. 766-773 8 p.

Research output: Contribution to journalReview article

54 Citations (Scopus)
2014

Eukaryotic elongation factor 2 kinase, an unusual enzyme with multiple roles

Kenney, J. W., Moore, C. E., Wang, X. & Proud, C., 1 Jan 2014, In : Advances in Biological Regulation. 55, p. 15-27 13 p.

Research output: Contribution to journalReview article

77 Citations (Scopus)

MAP kinase-interacting kinases - Emerging targets against cancer

Diab, S., Kumarasiri, M., Yu, M., Teo, T., Proud, C., Milne, R. & Wang, S., 24 Apr 2014, In : Chemistry and Biology. 21, 4, p. 441-452 12 p.

Research output: Contribution to journalReview article

59 Citations (Scopus)

MTORC1 signaling controls multiple steps in ribosome biogenesis

Iadevaia, V., Liu, R. & Proud, C., 1 Dec 2014, In : Seminars in Cell and Developmental Biology. 36, p. 113-120 8 p.

Research output: Contribution to journalReview article

83 Citations (Scopus)

Signaling crosstalk between the mTOR complexes

Jianling, X. & Proud, C. G., 2014, In : Translation (Austin, Tex.). 2, 1, p. e28174

Research output: Contribution to journalReview article

2012

Consolidation and translation regulation

Gal-Ben-Ari, S., Kenney, J. W., Ounalla-Saad, H., Taha, E., David, O., Levitan, D., Gildish, I., Panja, D., Pai, B., Wibrand, K., Simpson, T. I., Proud, C., Bramham, C. R., Armstrong, J. D. & Rosenblum, K., 1 Sep 2012, In : Learning and Memory. 19, 9, p. 410-422 13 p.

Research output: Contribution to journalReview article

52 Citations (Scopus)

On the diversification of the translation apparatus across eukaryotes

Hernández, G., Proud, C. G., Preiss, T. & Parsyan, A., 20 Jun 2012, In : Comparative and Functional Genomics. 2012, 256848.

Research output: Contribution to journalReview article

16 Citations (Scopus)

Roles of the mammalian target of rapamycin, mTOR, in controlling ribosome biogenesis and protein synthesis

Iadevaia, V., Huo, Y., Zhang, Z., Foster, L. J. & Proud, C. G., 1 Feb 2012, In : Biochemical Society Transactions. 40, 1, p. 168-172 5 p.

Research output: Contribution to journalReview article

46 Citations (Scopus)

Targeting Mnks for cancer therapy

Hou, J., Lam, F., Proud, C. & Wang, S., 1 Jan 2012, In : Oncotarget. 3, 2, p. 118-131 14 p.

Research output: Contribution to journalReview article

106 Citations (Scopus)

Vanishing white matter: The next 10 years

Proud, C., 1 Jan 2012, In : Future Neurology. 7, 1, p. 81-92 12 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)
2011

Differing effects of rapamycin and mTOR kinase inhibitors on protein synthesis

Huo, Y., Iadevaia, V. & Proud, C., 1 Apr 2011, In : Biochemical Society Transactions. 39, 2, p. 446-450 5 p.

Research output: Contribution to journalReview article

26 Citations (Scopus)

MTORC1 signaling: What we still dont know

Wang, X. & Proud, C., 1 Aug 2011, In : Journal of Molecular Cell Biology. 3, 4, p. 206-220 15 p.

Research output: Contribution to journalReview article

101 Citations (Scopus)
2009

mTOR's role in ageing: protein synthesis or autophagy?

Hands, S. L., Proud, C. & Wyttenbach, A., 1 Jan 2009, In : Aging. 1, 7, p. 586-597 12 p.

Research output: Contribution to journalReview article

134 Citations (Scopus)

Nutrient control of TORC1, a cell-cycle regulator

Wang, X. & Proud, C., 1 Jun 2009, In : Trends in Cell Biology. 19, 6, p. 260-267 8 p.

Research output: Contribution to journalReview article

133 Citations (Scopus)

Protein synthesis and its control in neuronal cells with a focus on vanishing white matter disease

Pavitt, G. D. & Proud, C., 27 Nov 2009, In : Biochemical Society Transactions. 37, 6, p. 1298-1310 13 p.

Research output: Contribution to journalReview article

44 Citations (Scopus)
2007

Shut-down of translation, a global neuronal stress response: Mechanisms and pathological relevance

Paschen, W., Proud, C. G. & Mies, G., 1 Jun 2007, In : Current Pharmaceutical Design. 13, 18, p. 1887-1902 16 p.

Research output: Contribution to journalReview article

27 Citations (Scopus)

Signalling to translation: How signal transduction pathways control the protein synthetic machinery

Proud, C. G., 15 Apr 2007, In : Biochemical Journal. 403, 2, p. 217-234 18 p.

Research output: Contribution to journalReview article

374 Citations (Scopus)

Translation matters: Protein synthesis defects in inherited disease

Scheper, G. C., Van Der Knaap, M. S. & Proud, C. G., 1 Sep 2007, In : Nature Reviews Genetics. 8, 9, p. 711-723 13 p.

Research output: Contribution to journalReview article

170 Citations (Scopus)
2006

Defective translation initiation causes vanishing of cerebral white matter

Scheper, G. C., Proud, C. G. & van der Knaap, M. S., 1 Apr 2006, In : Trends in Molecular Medicine. 12, 4, p. 159-166 8 p.

Research output: Contribution to journalReview article

26 Citations (Scopus)

The mTOR pathway in the control of protein synthesis

Wang, X. & Proud, C. G., 1 Oct 2006, In : Physiology. 21, 5, p. 362-369 8 p.

Research output: Contribution to journalReview article

386 Citations (Scopus)

When translation meets transformation: The mTOR story

Averous, J. & Proud, C. G., 16 Oct 2006, In : Oncogene. 25, 48, p. 6423-6435 13 p.

Research output: Contribution to journalReview article

159 Citations (Scopus)
2004

Ras, PI3-kinase and mTOR signaling in cardiac hypertrophy

Proud, C., 15 Aug 2004, In : Cardiovascular Research. 63, 3, p. 403-413 11 p.

Research output: Contribution to journalReview article

116 Citations (Scopus)

The multifaceted role of mTOR in cellular stress responses

Proud, C., 1 Aug 2004, In : DNA Repair. 3, 8-9, p. 927-934 8 p.

Research output: Contribution to journalReview article

71 Citations (Scopus)

Translation factors: In sickness and in health

Abbott, C. M. & Proud, C., 1 Jan 2004, In : Trends in Biochemical Sciences. 29, 1, p. 25-31 7 p.

Research output: Contribution to journalReview article

44 Citations (Scopus)
2003

Role of mTOR signalling in the control of translation initiation and elongation by nutrients

Proud, C., 8 Sep 2003, In : Current Topics in Microbiology and Immunology. 279, p. 215-244 30 p.

Research output: Contribution to journalReview article

90 Citations (Scopus)
2001

Regulation of eukaryotic initiation factor eIF2B.

Proud, C., 1 Jan 2001, In : Progress in molecular and subcellular biology. 26, p. 95-114 20 p.

Research output: Contribution to journalReview article

60 Citations (Scopus)
1997

Molecular mechanisms for the control of translation by insulin

Proud, C. & Denton, R. M., 1 Dec 1997, In : Biochemical Journal. 328, 2, p. 329-341 13 p.

Research output: Contribution to journalReview article

215 Citations (Scopus)
1996

GSK3: A SHAGGY frog story

Welsh, G. I., Wilson, C. & Proud, C., 1 Jan 1996, In : Trends in Cell Biology. 6, 7, p. 274-279 6 p.

Research output: Contribution to journalReview article

122 Citations (Scopus)

p70 S6 Kinase: An enigma with variations

Proud, C., 1 Jan 1996, In : Trends in Biochemical Sciences. 21, 5, p. 181-185 5 p.

Research output: Contribution to journalReview article

196 Citations (Scopus)

The role of eIF4 in cell proliferation

Flynn, A. & Proud, C. G., 11 Nov 1996, In : Cancer Surveys. 27, p. 293-310 18 p.

Research output: Contribution to journalReview article

86 Citations (Scopus)
1995

PKR: a new name and new roles

Proud, C., 1 Jan 1995, In : Trends in Biochemical Sciences. 20, 6, p. 241-246 6 p.

Research output: Contribution to journalReview article

195 Citations (Scopus)
1994

Molecular mechanisms in the control of translation by hormones and growth factors

Redpath, N. T. & Proud, C., 1 Jan 1994, In : BBA - Molecular Cell Research. 1220, 2, p. 147-162 16 p.

Research output: Contribution to journalReview article

82 Citations (Scopus)
1978

How does insulin stimulate glycogen synthesis?

Cohen, P., Nimmo, H. G. & Proud, C., 1 Dec 1978, In : Biochemical Society Symposia. No.43, p. 69-95 27 p.

Research output: Contribution to journalReview article

35 Citations (Scopus)