Christopher Proud

Professor

  • 19991 Citations
  • 80 h-Index
1975 …2019
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Research Output 1975 2019

2019

Ablation of elongation factor 2 kinase enhances heat-shock protein 90 chaperone expression and protects cells under proteotoxic stress

Xie, J., Van Damme, P., Fang, D. & Proud, C., 1 Jan 2019, In : Journal of Biological Chemistry. 294, 18, p. 7169-7176 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Design, synthesis and activity of Mnk1 and Mnk2 selective inhibitors containing thieno[2,3-d]pyrimidine scaffold

Jin, X., Merrett, J., Tong, S., Flower, B., Xie, J., Yu, R., Tian, S., Gao, L., Zhao, J., Wang, X., Jiang, T. & Proud, C., 15 Jan 2019, In : European Journal of Medicinal Chemistry. p. 735-751 17 p.

Research output: Contribution to journalArticle

Eukaryotic elongation factor 2 kinase promotes angiogenesis in hepatocellular carcinoma via PI3K/Akt and STAT3

Zhou, Y., Li, Y., Xu, S., Lu, J., Zhu, Z., Chen, S., Tan, Y., He, P., Xu, J., Proud, C., Xie, J. & Shen, K., 8 Jul 2019, In : International Journal of Cancer.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Phosphorylation and signal transduction pathways in translational control

Proud, C., 1 Jul 2019, In : Cold Spring Harbor Perspectives in Biology. 11, 7, a033050.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan

Xie, J., de Souza Alves, V., von der Haar, T., O'Keefe, L., Lenchine, R. V., Jensen, K. B., Liu, R., Coldwell, M. J., Wang, X. & Proud, C. G., 4 Feb 2019, In : Current Biology. 29, 5

Research output: Contribution to journalArticle

The ability to utilise ammonia as nitrogen source is cell type specific and intricately linked to GDH, AMPK and mTORC1

Lie, S., Wang, T., Forbes, B., Proud, C. G. & Petersen, J., 6 Feb 2019, In : Scientific Reports. 9, 1, 1461.

Research output: Contribution to journalArticle

3 Citations (Scopus)

The MAP kinase-interacting kinases (MNKs) as targets in oncology

Xie, J., Merrett, J. E., Jensen, K. B. & Proud, C. G., 4 Mar 2019, In : Expert Opinion on Therapeutic Targets. 23, 3, p. 187-199 13 p.

Research output: Contribution to journalArticle

Transcriptional and metabolic rewiring of colorectal cancer cells expressing the oncogenic KRASG13D mutation

Charitou, T., Srihari, S., Lynn, M., Jarboui, M. A., Fasterius, E., Moldovan, M., Shirasawa, S., Tsunoda, T., Ueffing, M., Xie, J., Xin, J., Wang, X., Proud, C., Boldt, K., Al-Khalili Szigyarto, C., Kolch, W. & Lynn, D., 2 Jul 2019, In : British Journal of Cancer. 121, 1, p. 37-50 14 p.

Research output: Contribution to journalArticle

2018
2 Citations (Scopus)

Adult mouse eIF2Bϵ Arg191His astrocytes display a normal integrated stress response in vitro

Wisse, L. E., Ter Braak, T. J., Van De Beek, M. C., Van Berkel, C. G. M., Wortel, J., Heine, V. M., Proud, C., Van Der Knaap, M. S. & Abbink, T. E. M., 1 Jan 2018, In : Scientific Reports. 8, 1, 3773.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Eukaryotic elongation factor 2 kinase upregulates the expression of proteins implicated in cell migration and cancer cell metastasis

Xie, J., Shen, K., Lenchine, R. V., Gethings, L. A., Trim, P. J., Snel, M. F., Zhou, Y., Kenney, J. W., Kamei, M., Kochetkova, M., Wang, X. & Proud, C. G., 1 May 2018, In : International Journal of Cancer. 142, 9, p. 1865-1877 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Lysosomal N-acetyltransferase interacts with ALIX and is detected in extracellular vesicles

Fedele, A. O., Isenmann, S., Kamei, M., Snel, M., Trim, P., Proud, C. & Hopwood, J., 1 Oct 2018, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1865, 10, p. 1451-1464 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Non-high-density lipoprotein cholesterol is more informative than traditional cholesterol indices in predicting diabetes risk for women with normal glucose tolerance

Liu, L., Li, Q., Yuan, Z., Zhao, M., Zhang, X., Zhang, H., Zheng, D., Xu, J., Gao, L., Guan, Q., Zhao, J., Proud, C. G., Wang, X., Hou, X. & REACTION Study Group, Nov 2018, In : Journal of Diabetes Investigation. 9, 6, p. 1304-1311 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Osteocalcin-dependent regulation of glucose metabolism and fertility: Skeletal implications for the development of insulin resistance

Tangseefa, P., Martin, S. K., Fitter, S., Baldock, P. A., Proud, C. G. & Zannettino, A. C. W., 1 May 2018, In : Journal of Cellular Physiology. 233, 5, p. 3769-3783 15 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Who does TORC2 talk to?

Xie, J., Wang, X. & Proud, C. G., 24 May 2018, In : Biochemical Journal. 475, 10, p. 1721-1738 18 p.

Research output: Contribution to journalReview article

2017
3 Citations (Scopus)
8 Citations (Scopus)

A novel role for CRTC2 in hepatic cholesterol synthesis through SREBP-2

Li, Y., Song, Y., Zhao, M., Guo, Y., Yu, C., Chen, W., Shao, S., Xu, C., Zhou, X., Zhao, L., Zhang, Z., Bo, T., Xia, Y., Proud, C. G., Wang, X., Wang, L., Zhao, J. & Gao, L., 1 Aug 2017, In : Hepatology. 66, 2, p. 481-497 17 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Direct and indirect activation of eukaryotic elongation factor 2 kinase by AMP-activated protein kinase

Johanns, M., Pyr dit Ruys, S., Houddane, A., Vertommen, D., Herinckx, G., Hue, L., Proud, C. & Rider, M. H., 1 Aug 2017, In : Cellular Signalling. 36, p. 212-221 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures

Heise, C., Taha, E., Murru, L., Ponzoni, L., Cattaneo, A., Guarnieri, F. C., Montani, C., Mossa, A., Vezzoli, E., Ippolito, G., Zapata, J., Barrera, I., Ryazanov, A. G., Cook, J., Poe, M., Stephen, M. R., Kopanitsa, M., Benfante, R., Rusconi, F., Braida, D. & 9 othersFrancolini, M., Proud, C. G., Valtorta, F., Passafaro, M., Sala, M., Bachi, A., Verpelli, C., Rosenblum, K. & Sala, C., 1 Mar 2017, In : Cerebral Cortex. 27, 3, p. 2226-2248 23 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Eukaryotic elongation factor 2 kinase (eEF2K) in cancer

Wang, X., Xie, J. & Proud, C., 1 Dec 2017, In : Cancers. 9, 12, 162.

Research output: Contribution to journalReview article

19 Citations (Scopus)

mTORC1 plays an important role in skeletal development by controlling preosteoblast differentiation

Fitter, S., Matthews, M. P., Martin, S. K., Xie, J., Ooi, S. S., Walkley, C. R., Codrington, J. D., Ruegg, M. A., Hall, M. N., Proud, C. G., Gronthos, S. & Zannettino, A. C. W., 1 Jan 2017, In : Molecular and Cellular Biology. 37, 7, e00668-16.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology

Brace, P. T., Tezera, L. B., Bielecka, M. K., Mellows, T., Garay, D., Tian, S., Rand, L., Green, J., Jogai, S., Steele, A. J., Millar, T. M., Sanchez-Elsner, T., Friedland, J. S., Proud, C. & Elkington, P. T., 1 Jan 2017, In : PLoS Pathogens. 13, 6, e1006367.

Research output: Contribution to journalArticle

274 Citations (Scopus)

Nusinersen versus sham control in infantile-onset spinal muscular atrophy

Finkel, R. S., Mercuri, E., Darras, B. T., Connolly, A. M., Kuntz, N. L., Kirschner, J., Chiriboga, C. A., Saito, K., Servais, L., Tizzano, E., Topaloglu, H., Tulinius, M., Montes, J., Glanzman, A. M., Bishop, K., Zhong, Z. J., Gheuens, S., Bennett, C. F., Schneider, E., Farwell, W. & 378 othersDe Vivo, D. C., Bradley, W. G., Schroth, M. K., Bodensteriner, J. B., Davis, C. S., Shell, R., Hen, J., Austin, E. D., Aziz-Zaman, S., Cappell, J., Constantinescu, A., Cruz, R., Dastgir, J., Dunaway, S., Engelstad, K., Gormley, M., Holuba La Marca, N., Khandji, A., Kramer, S., Marra, J., Ortiz-Miller, C., Popolizio, M., Salazar, R., Sanabria, L., Weimer, L., Anand, P., Gadeken, R., Golumbek, P. T., Siener, C., Zaidman, C. M., Al-Ghamdi, F., Berde, C., Ghosh, P., Graham, R., Harrington, T., Koka, A., Laine, R., Liew, W., Mirek, E., Ordonez, G., Pasternak, A., Quigley, J., Sethna, N., Souris, M., Szelag, H., Wand, L., Day, J. W., D'Souza, G., Duong, T. T., Gee, R., Kitsuwa-Lowe, J., McFall, D., Patnaik, S., Paulose, S., Perez, J., Proud, C., Purse, B., Ramamurthi, R. J., Sakamuri, S., Sampson, J., Sanjanwala, B., Tesi Rocha, A. C., Watson, K., Welsh, L., Pena, L. D. M., Case, L., Coates, J., DeArmey, S., Homi, M. M., Milleson, C., Nelson, N., Ross, A., Smith, E., Taicher, B., Wootton, J., Finanger, E., Benjamin, D., Frank, A., Roberts, C., Russman, B., Zilke, K., Berry, D., Civitello, M., Cook, D., Endsley, J. D., Johnson, C., Kasper, M., Leon, W., Lim, A., O'Reardon, K., Sigurdardottir, L. Y., Turner, J., Weber-Guzman, F., Zinn, M., Iannaccone, S. T., Castro, D., Cowie, M., Farrow-Gillespie, A., Herbert, A., Kauk, M., McElroy, D., Miller, N., Nelson, L., Smith, L., Spain, T., Trest, S., Johnson, N., Butterfield, R., DiBella, D., Mayne, K., Newcomb, T. M., Rausch, N., Blomgren, C., Choi, H. W., Epstein, L., Goldman, S., Krosschell, K., Krueger, J., Kurz, J., Rao, V., Parsons, J., Allen, V., Bielsky, A., Booker, K., Camuto, A., Carry, T., Fuhr, P., Gibbons, M., Janas, J., Johnson, H., Kelly, C., Lord-Halvorson, L. S., Nicolarsen, S., Shea, S., Tran, V., VanderVeen, G., Yang, M., Zimmerman, C., Shieh, P., Parziale, N., Rao, L., Said, J. W., Shu, F., Skura, C., Staudt, L., Tennekoon, G., Adang, L., Brandsema, J., Chadehumbe, M., Flickinger, J., Kichula, E., Stanford, D., Toms, M., Zigmont, J., Oskoui, M., Arpin, S., Dinunzio, P., Ingelmo, P. M., Poulin, C., Rivera, G., Sabapathy, C., Srour, M., Turgeon-Desilet, S., Zielinski, D., Selby, K., King, C., Lee, J., Michoulas, A., Roland, E., Vajsar, J., Chau, V., Dowling, J., Haldenby, R., Miki, M., So, S., Pascual Pascual, S. I., Martinez Bermejo, A., Epinosa Garcia, S., Garcia Guixot, S., Martinez Moreno, M. M., del Pilar Tirado Requero, M., del Mar Garcia Romero, M., Aguilar, C., Munell Casadesus, F., Gomez Garcia de la Banda, M. B., Gallardo, M., Gili, G., Alavarez Molinero, M., de Los Angeles Tormos Munoz, M., Palacios, N. J., Planas Pascual, B., del Mar Melendez Plumed, M., Rucian, A. F., Toro Tamargo, E., Gratacos Vinola, M., Borell, S., Eckenweiler, M., Krüger, M., Pechmann, A., Rippberger, B., Stein, S., Vogt, S., Wider, S., Schara, U., Andres, B., Della Marina, A., Ganfuss, A., Jachertz, P., Koelbel, H., Rupprich, K., Schroers, E. S., Sponemann, N., Bruno, C., Fiorillo, C., Garaventa, A., Lanteri, P., Lanzillotta, V., Manzitti, C., Pedermonte, M., Tacchetti, P., Trucco, F., Zuffi, A., De Sanctis, R., Fanelli, L., Luigetti, M., Palermo, C., Pane, M., Piastra, M., Sivo, S., Gargaun, E., Gidaro, T., Gilabert, S., Léger, P. L., Le Moing, A. G., Lilien, C., Mayer, M., Ollievier, Q., Rambaud, J., Taytard, J., Vialle, R., Voit, T., Muntoni, F., D'Argenzio, L., Lister, PH., Manzur, A., Pisco Domingos, J., Ramsey, D., Ricotti, V., Schottlaender, L., Scoto, M., Scuplak, S. M., Selby, V., Straub, V., Baily, S., Bertoli, M., Mayhew, A. G., Lofra, R. M., Murphy, A., Wood, C., Darin, N., Eldblom, J., Kimber, E., Kroksmark, A. K., Lindstedt, A., Michael, E., Sofou, K., Deconinck, N., Christiaens, A., Coppens, S., DeCock, K., De Vos voor, E., Dorban, F., Gilbert, G., Rooze, S., Tahon, V., Van Coster, R., Van Der Looven, R., Vanlander, A., Vens, D., Verhelst, H., Wenderickx, B., Wittevrongel, S., Farrar, M., Berthon-Jones, N., Doumit, M. A., Herbert, K. J., Kandula, T., Morrison, M., O'Brien, J., Richardson, S., Ferreira Sampaio, H. A., Teoh, H. L., Ryan, M., Carroll, K. M., De Valle, K. L., Villano, D., Woodcock, I., Yiu, E. M., Ardicli, D., Gunbey, C., Haliloglu, V. G., Karaduman, A. A., Konuskan, B., Yildiz Sarikaya, F. G., Serdaroglu, E., Tanyildiz, M., Temucin, C. M., Yildirim, M., Yilmaz, O. T., Arakawa, R., Chiba, Y., Eto, K., Hirasawa, K., Ikai, T., Ito, S., Ito, Y., Kaburagi, Y., Kaneko, H., Matsumaru, S., Matsushima, N., Mizuochi, K., Nagata, S., Nakatsukasa, H., Nishikawa, A., Otani, Y., Sato, T., Shichiji, M., Sugimoto, K., Takeshita, A., Yanagishita, T., Yamauchi, A., Takeshima, Y., Fujino, T., Fukuda, N., Lee, T., Oriyama, K., Shibano, T., Shimomura, H., Tachikawa, T., Tanaka, Y., Taniguchi, N., Chae, J. H., Choi, S. A., Chun, S. M., Jo, H., Kim, H., Kim, S. Y., Lee, J. S., Lim, B. C., Shin, H. I., Son, W. S., Chan, S., Chung, A. C., Yan, C. S., Stella, C., Joseph, C. K. W., Ng, C. S., Alvin, H. C. C., Janice, I. J. K., Wendy, L. W. M., Chui-San, M. N., Ki, N. Y., Shun, T. N., Connie, W. Y., Virginia, W. C., Yvonne, Y., Jong, Y. J., Chen, T. H., Chou, P. C., Chou, Y. H., Chung, H. W., Hsu, J. H., Ju, Y. H., Liang, W. C., Shih, H. H., Wang, H. Y., Wu, Y. C. & Zeng, Y. S., 2 Nov 2017, In : New England Journal of Medicine. 377, 18, p. 1723-1732 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Oncogenic MNK signalling regulates the metastasis suppressor NDRG1

Tian, S., Wang, X. & Proud, C. G., 1 Jan 2017, In : Oncotarget. 8, 28, p. 46121-46135 15 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Proteomic and metabolomic analyses of vanishing white matter mouse astrocytes reveal deregulation of ER functions

Wisse, L. E., Penning, R., Zaal, E. A., van Berkel, C. G. M., ter Braak, T. J., Polder, E., Kenney, J. W., Proud, C., Berkers, C. R., Altelaar, M. A. F., Speijer, D., van der Knaap, M. S. & Abbink, T. E. M., 20 Dec 2017, In : Frontiers in Cellular Neuroscience. 11, 411.

Research output: Contribution to journalArticle

2016
4 Citations (Scopus)

A high-throughput screening assay for eukaryotic elongation factor 2 kinase inhibitors

Xiao, T., Liu, R., Proud, C. G. & Wang, M. W., 1 Oct 2016, In : Acta Pharmaceutica Sinica B. 6, 6, p. 557-563 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Characterization of p75 neurotrophin receptor expression in human dental pulp stem cells

Pan, W., Kremer, K. L., Kaidonis, X., Ludlow, V. E., Rogers, M. L., Xie, J., Proud, C. G. & Koblar, S. A., 1 Oct 2016, In : International Journal of Developmental Neuroscience. 53, p. 90-98 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Depletion of ribosomal protein S19 causes a reduction of rRNA synthesis

Juli, G., Gismondi, A., Monteleone, V., Caldarola, S., Iadevaia, V., Aspesi, A., Dianzani, I., Proud, C. G. & Loreni, F., 13 Oct 2016, In : Scientific Reports. 6, 35026.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Elongation factor 2 kinase promotes cell survival by inhibiting protein synthesis without inducing autophagy

Moore, C. E. J., Wang, X., Xie, J., Pickford, J., Barron, J., Regufe da Mota, S., Versele, M. & Proud, C. G., 1 Apr 2016, In : Cellular Signalling. 28, 4, p. 284-293 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Erratum: mTORC2 is a tyrosine kinase (Cell Research (2016) 26 (1-2) DOI:10.1038/cr.2015.134)

Wang, X. & Proud, C. G., 1 Feb 2016, In : Cell Research. 26, 2, 1 p.

Research output: Contribution to journalComment/debate

20 Citations (Scopus)

Eukaryotic elongation factor 2 kinase as a drug target in cancer, and in cardiovascular and neurodegenerative diseases

Liu, R. & Proud, C., 1 Mar 2016, In : Acta Pharmacologica Sinica. 37, 3, p. 285-294 10 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)

Eukaryotic elongation factor 2 kinase regulates the synthesis of microtubule-related proteins in neurons

Kenney, J. W., Genheden, M., Moon, K. M., Wang, X., Foster, L. J. & Proud, C. G., 1 Jan 2016, In : Journal of Neurochemistry. 136, 2, p. 276-284 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

GCN2 contributes to mTORC1 inhibition by leucine deprivation through an ATF4 independent mechanism

Averous, J., Lambert-Langlais, S., Mesclon, F., Carraro, V., Parry, L., Jousse, C., Bruhat, A., Maurin, A. C., Pierre, P., Proud, C. G. & Fafournoux, P., 14 Jun 2016, In : Scientific Reports. 6, 27698.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Glycine restores the anabolic response to leucine in a mouse model of acute inflammation

Ham, D. J., Caldow, M. K., Chhen, V., Chee, A., Wang, X., Proud, C. G., Lynch, G. S. & Koopman, R., 1 Jun 2016, In : American Journal of Physiology - Endocrinology and Metabolism. 310, 11, p. E970-E981

Research output: Contribution to journalArticle

3 Citations (Scopus)

MNK1 and MNK2 mediate adverse effects of high-fat feeding in distinct ways

Moore, C. E. J., Pickford, J., Cagampang, F. R., Stead, R. L., Tian, S., Zhao, X., Tang, X., Byrne, C. D. & Proud, C. G., 18 Apr 2016, In : Scientific Reports. 6, 23476.

Research output: Contribution to journalArticle

14 Citations (Scopus)

MTORC1 signalling and eIF4E/4E-BP1 translation initiation factor stoichiometry influence recombinant protein productivity from GSCHOK1 cells

Jossé, L., Xie, J., Proud, C. G. & Smales, C. M., 1 Jan 2016, In : Biochemical Journal. 473, 24, p. 4651-4664 14 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

mTORC2 is a tyrosine kinase

Wang, X. & Proud, C. G., 1 Jan 2016, In : Cell Research. 26, 1, p. 1-2 2 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

mTOR inhibitors in cancer therapy [version 1; referees: 3 approved]

Xie, J., Wang, X. & Proud, C. G., 2016, In : F1000Research. 5, 2078.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Quantitative non-canonical amino acid tagging (QuaNCAT) proteomics identifies distinct patterns of protein synthesis rapidly induced by hypertrophic agents in cardiomyocytes, revealing new aspects of metabolic remodeling

Liu, R., Kenney, J. W., Manousopoulou, A., Johnston, H. E., Kamei, M., Woelk, C. H., Xie, J., Schwarzer, M., Garbis, S. D. & Proud, C. G., 1 Oct 2016, In : Molecular and Cellular Proteomics. 15, 10, p. 3170-3189 20 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Role of AMPK in regulation of LC3 lipidation as a marker of autophagy in skeletal muscle

Fritzen, A. M., Frøsig, C., Jeppesen, J., Jensen, T. E., Lundsgaard, A. M., Serup, A. K., Schjerling, P., Proud, C., Richter, E. A. & Kiens, B., 1 Jun 2016, In : Cellular Signalling. 28, 6, p. 663-674 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Stoichiometry of the eIF2B complex is maintained by mutual stabilization of subunits

Wortham, N. C., Stewart, J. D., Harris, S., Coldwell, M. J. & Proud, C. G., 1 Mar 2016, In : Biochemical Journal. 473, 5, p. 571-580 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Tuning Specific Translation in Cancer Metastasis and Synaptic Memory: Control at the MNK–eIF4E Axis

Bramham, C. R., Jensen, K. B. & Proud, C. G., 1 Oct 2016, In : Trends in Biochemical Sciences. 41, 10, p. 847-858 12 p.

Research output: Contribution to journalReview article

2015
8 Citations (Scopus)

ABC50 mutants modify translation start codon selection

Stewart, J. D., Cowan, J. L., Perry, L. S., Coldwell, M. J. & Proud, C. G., 15 Apr 2015, In : Biochemical Journal. 467, 2, p. 217-229 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

BDNF stimulation of protein synthesis in cortical neurons requires the MAP kinase-interacting kinase MNK1

Genheden, M., Kenney, J. W., Johnston, H. E., Manousopoulou, A., Garbis, S. D. & Proud, C. G., 21 Jan 2015, In : Journal of Neuroscience. 35, 3, p. 972-984 13 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Dissecting the signaling pathways that mediate cancer in PTEN and LKB1 double-knockout mice

Chen, J., Zhang, X. D. & Proud, C., 1 Jan 2015, In : Science Signaling. 8, 392, pe1.

Research output: Contribution to journalReview article

10 Citations (Scopus)

Dynamics of elongation factor 2 kinase regulation in cortical neurons in response to synaptic activity

Kenney, J. W., Sorokina, O., Genheden, M., Sorokin, A., Douglas Armstrong, J. & Proud, C., 1 Jan 2015, In : Journal of Neuroscience. 35, 7, p. 3034-3037 4 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

EIF2B: Recent structural and functional insights into a key regulator of translation

Wortham, N. C. & Proud, C. G., 1 Dec 2015, In : Biochemical Society Transactions. 43, p. 1234-1240 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Elongation factor 2 kinase is regulated by proline hydroxylation and protects cells during hypoxia

Moore, C. E. J., Mikolajek, H., Da Mota, S. R., Wang, X., Kenney, J. W., Werner, J. M. & Proud, C. G., 1 Jan 2015, In : Molecular and Cellular Biology. 35, 10, p. 1788-1804 17 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway

Bommer, U. A., Iadevaia, V., Chen, J., Knoch, B., Engel, M. & Proud, C. G., 1 Aug 2015, In : Cellular Signalling. 27, 8, p. 1557-1568 12 p.

Research output: Contribution to journalArticle