Christopher Proud

Professor, PhD, BSc

  • 21429 Citations
  • 83 h-Index
1975 …2020

Research output per year

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Personal profile

Public Profile

Professor Chris Proud has held numerous positions as lecturer, reader or professor in universities in the UK, Germany and Canada.
 
At the University of Dundee (Scotland), alongside his duties as Head of the Division of Molecular Physiology, he also coordinated the Medical Research Council Nutrient Sensing & Signalling Research Group.
 
From 2005-2008, he was Head of the Department of Biochemistry & Molecular Biology at the University of British Columbia, in Vancouver, Canada, where he continued his research into the molecular mechanisms that regulate protein synthesis. He also served as co-Director of that University’s Life Sciences Institute.
Chris worked at the University of Southampton from 2008 – 2014 where he led a substantial research team studying the mechanisms that control protein synthesis and ribosome biogenesis. He studied their roles in metabolic diseases such as diabetes, in cancer, in cardiovascular disorders, and in neurological processes.
He has supervised more than forty MSc or PhD students and almost fifty postdoctoral researchers.
In September 2014 Chris moved to Adelaide to take up the position of Theme Leader: Nutrition and Metabolism at the SAHMRI.
 
Chris is also a Professor in Molecular and Biomedical Science at the University of Adelaide.
 
Chris is a member of the Editorial Boards of the Biochemical Journal and f1000 Research. He holds a Visiting Professorship at China Ocean University in Qingdao.
 
His research at SAHMRI includes studies on the regulation of protein synthesis nutrients and hormones; cancer cell biology; and the molecular mechanisms involved in diet-induced inflammation, insulin resistance and type 2 diabetes. Much of this research focuses on protein kinases that control the protein synthesis machinery, i.e., mammalian target of rapamycin (mTOR), eukaryotic elongation factor 2 kinase (eEF2K) and the MAP kinase-interacting kinases (MNKs).
 
Since 2016, he has also been Director of the Lysosomal Diseases Research Unit at SAHMRI (the LDRU). In 2019, Chris was appointed to the position of Theme Leader: Lifelong Health at SAHMRI.

Education/Academic qualification

University of Bristol

University of Dundee

External positions

Visiting Professor, Ocean University of China

Professor in Molecular and Biomedical Science, University of Adelaide

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Research Output

Chloroquine and bafilomycin A mimic lysosomal storage disorders and impair mTORC1 signalling

Fedele, A. O. & Proud, C., Apr 2020, In : Bioscience Reports. 40, 4, BSR20200905.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Disabling MNK protein kinases promotes oxidative metabolism and protects against diet-induced obesity

Sandeman, L. Y., Kang, W. X., Wang, X., Jensen, K. B., Wong, D., Bo, T., Gao, L., Zhao, J., Byrne, C. D., Page, A. J. & Proud, C. G., Dec 2020, In : Molecular Metabolism. 42, 101054.

Research output: Contribution to journalArticle

Open Access

eEF2/eEF2K Pathway in the mature dentate gyrus determines neurogenesis level and cognition

Taha, E., Patil, S., Barrera, I., Panov, J., Khamaisy, M., Proud, C. G., Bramham, C. R. & Rosenblum, K., 21 Sep 2020, In : Current Biology. 30, 18, p. 3507-3521.e7

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Identification of DNA response elements regulating expression of CCAAT/enhancer-binding protein (C/EBP) β and δ and MAP kinase-interacting kinases during early adipogenesis

Merrett, J. E., Bo, T., Psaltis, P. J. & Proud, C. G., 1 Jan 2020, In : Adipocyte. 9, 1, p. 427-442 16 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)