Ben Wang

Dr

  • 93 Citations
  • 4 h-Index
20102015
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Ben has a keen interest in cell signalling and protein trafficking research in different disease models. Ben graduated from Tongji University, Shanghai in 2008. He went on to complete his Masters at the University of Wollongong, studying the role of cell surface receptor P2X7 in immunity and inflammation. From 2012-2015 he undertook his Ph.D. with Professor Peter Gunning at UNSW in Sydney, investigated the mechanism of actin cytoskeleton-binding protein tropomyosin in regulating cell proliferation in a transgenic mouse model and validated tropomyosin as a therapeutic target in the treatment of melanoma. Subsequently, he joined Nanyang Technology University in Singapore as a post-doctural researcher, dissecting the novel role of a G associated protein in the Hedgehog signaling pathway and basal cell carcinoma. He joined the Hopwood Centre for Neurobiology (formally the Lysosomal Diseases Research Unit) at SAHMRI in 2017 working with A/Professor Pirjo Apaja’s group. His current interest is on the signalling pathways involved in protein networks of the organelle function, and their association with neuron diseases

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Research Output 2010 2015

  • 93 Citations
  • 4 h-Index
  • 4 Article
27 Citations (Scopus)

Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments

Schevzov, G., Kee, A. J., Wang, B., Sequeira, V. B., Hook, J., Coombes, J. D., Lucas, C. A., Stehn, J. R., Musgrove, E. A., Cretu, A., Assoian, R., Fath, T., Hanoch, T., Seger, R., Pleines, I., Kile, B. T., Hardeman, E. C. & Gunning, P. W., 1 Jul 2015, In : Molecular Biology of the Cell. 26, 13, p. 2475-2490 16 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

P2X7 receptor activation induces reactive oxygen species formation in erythroid cells

Wang, B. & Sluyter, R., 1 Jan 2013, In : Purinergic Signalling. 9, 1, p. 101-112 12 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

P2X7 receptor activation induces cell death and CD23 shedding in human RPMI 8226 multiple myeloma cells

Farrell, A. W., Gadeock, S., Pupovac, A., Wang, B., Jalilian, I., Ranson, M. & Sluyter, R., 1 Nov 2010, In : Biochimica et Biophysica Acta - General Subjects. 1800, 11, p. 1173-1182 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

P2X7 receptor activation induces cell death and microparticle release in murine erythroleukemia cells

Constantinescu, P., Wang, B., Kovacevic, K., Jalilian, I., Bosman, G. J. C. G. M., Wiley, J. S. & Sluyter, R., Sep 2010, In : Biochimica et Biophysica Acta - Biomembranes. 1798, 9, p. 1797-1804 8 p.

Research output: Contribution to journalArticle