Andrew Zannettino

Professor

  • 11097 Citations
  • 57 h-Index
1994 …2020

Research output per year

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Research Output

2020

Allogeneic primary mesenchymal stem/stromal cell aggregates within poly(N-isopropylacrylamide-co-acrylic acid) hydrogel for osteochondral regeneration

Zhang, J., Zhang, M., Lin, R., Yun, S., Du, Y., Wang, L., Yao, Q., Zannettino, A. & Zhang, H., 1 Mar 2020, In : Applied Materials Today. 18, 100487.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Characterisation and evaluation of the regenerative capacity of Stro-4+ enriched bone marrow mesenchymal stromal cells using bovine extracellular matrix hydrogel and a novel biocompatible melt electro-written medical-grade polycaprolactone scaffold

Black, C., Kanczler, J. M., de Andrés, M. C., White, L. J., Savi, F. M., Bas, O., Saifzadeh, S., Henkel, J., Zannettino, A., Gronthos, S., Woodruff, M. A., Hutmacher, D. W. & Oreffo, R. O. C., 1 Jul 2020, In : Biomaterials. 247, 119998.

Research output: Contribution to journalArticle

GLIPR1 expression is reduced in multiple myeloma but is not a tumour suppressor in mice

Friend, N., Noll, J., Opperman, K. S., Clark, K. C., Mrozik, K., Vandyke, K., Hewett, D. & Zannettino, A., 1 Jan 2020, In : PLoS ONE. 15, 1, e0228408.

Research output: Contribution to journalArticle

P0-Related Protein Accelerates Human Mesenchymal Stromal Cell Migration by Modulating VLA-5 Interactions with Fibronectin

Roubelakis, M. G., Tsaknakis, G., Lyu, F. J., Trohatou, O., Zannettino, A. C. W. & Watt, S. M., 29 Apr 2020, In : Cells. 9, 5

Research output: Contribution to journalArticle

Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis

Xie, J., Shen, K., Jones, A. T., Yang, J., Tee, A. R., Shen, M. H., Yu, M., Irani, S., Wong, D., Merrett, J. E., Lenchine, R. V., De Poi, S., Jensen, K., Trim, P., Snel, M., Kamei, M., Martin, S., Fitter, S., Tian, S., Wang, X. & 3 others, Butler, L., Zannettino, A. & Proud, C., 1 Jan 2020, In : Cellular and Molecular Life Sciences.

Research output: Contribution to journalArticle

Tunable Biomimetic Hydrogels from Silk Fibroin and Nanocellulose

Dorishetty, P., Balu, R., Athukoralalage, S. S., Greaves, T. L., Mata, J., De Campo, L., Saha, N., Zannettino, A., Dutta, N. K. & Choudhury, N. R., 17 Feb 2020, In : ACS Sustainable Chemistry and Engineering. 8, 6, p. 2375-2389 15 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2019

A niche-dependent myeloid transcriptome signature defines dormant myeloma cells

Khoo, W. H., Ledergor, G., Weiner, A., Roden, D. L., Terry, R. L., McDonald, M. M., Chai, R. C., De Veirman, K., Owen, K. L., Opperman, K. S., Vandyke, K., Clark, J. R., Seckinger, A., Kovacic, N., Nguyen, A., Mohanty, S. T., Pettitt, J. A., Xiao, Y., Corr, A. P., Seeliger, C. & 14 others, Novotny, M., Lasken, R. S., Nguyen, T. V., Oyajobi, B. O., Aftab, D., Swarbrick, A., Parker, B., Hewett, D., Hose, D., Vanderkerken, K., Zannettino, A., Amit, I., Phan, T. G. & Croucher, P. I., 4 Jul 2019, In : Blood. 134, 1, p. 30-43 14 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Clodronate-Liposome Mediated Macrophage Depletion Abrogates Multiple Myeloma Tumor Establishment In Vivo

Opperman, K. S., Vandyke, K., Clark, K. C., Coulter, E. A., Hewett, D. R., Mrozik, K. M., Schwarz, N., Evdokiou, A., Croucher, P. I., Psaltis, P., Noll, J. E. & Zannettino, A., 1 Aug 2019, In : Neoplasia (United States). 21, 8, p. 777-787 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
1 Citation (Scopus)

Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability

Dutta, A. K., Fink, J. L., Grady, J. P., Morgan, G. J., Mullighan, C. G., To, L. B., Hewett, D. R. & Zannettino, A., 1 Feb 2019, In : Leukemia. 33, 2, p. 457-468 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2018

Co-fuse: a new class discovery analysis tool to identify and prioritize recurrent fusion genes from RNA-sequencing data

Paisitkriangkrai, S., Quek, K., Nievergall, E., Jabbour, A., Zannettino, A. & Kok, C., 1 Oct 2018, In : Molecular Genetics and Genomics. 293, 5, p. 1217-1229 13 p.

Research output: Contribution to journalArticle

Enhanced multi-lineage differentiation of human mesenchymal stem/stromal cells within poly(: N -isopropylacrylamide-acrylic acid) microgel-formed three-dimensional constructs

Zhang, J., Yun, S., Bi, J., Dai, S., Du, Y., Zannettino, A. & Zhang, H., 1 Jan 2018, In : Journal of Materials Chemistry B. 6, 12, p. 1799-1814 16 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Mesenchymal progenitor cells primed with pentosan polysulfate promote lumbar intervertebral disc regeneration in an ovine model of microdiscectomy

Daly, C. D., Ghosh, P., Zannettino, A., Badal, T., Shimmon, R., Jenkin, G., Oehme, D., Jain, K., Sher, I., Vais, A., Cohen, C., Chandra, R. V. & Goldschlager, T., 1 Mar 2018, In : Spine Journal. 18, 3, p. 491-506 16 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis

Martin, S. K., Fitter, S., El Khawanky, N., Grose, R., Walkley, C. R., Purton, L. E., Ruegg, M. A., Hall, M. N., Gronthos, S. & Zannettino, A., 1 Dec 2018, In : Scientific Reports. 8, 1, 14501.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Osteocalcin-dependent regulation of glucose metabolism and fertility: Skeletal implications for the development of insulin resistance

Tangseefa, P., Martin, S. K., Fitter, S., Baldock, P. A., Proud, C. G. & Zannettino, A. C. W., 1 May 2018, In : Journal of Cellular Physiology. 233, 5, p. 3769-3783 15 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Osteopontin in the pathophysiology of obesity: Is Opn a fat cell foe?

Fitter, S. & Zannettino, A., 1 May 2018, In : Obesity Research and Clinical Practice. 12, 3, p. 249-250 2 p.

Research output: Contribution to journalEditorial

2 Citations (Scopus)

Translation of remote control regenerative technologies for bone repair

Markides, H., McLaren, J. S., Telling, N. D., Alom, N., Al-Mutheffer, E. A., Oreffo, R. O. C., Zannettino, A., Scammell, B. E., White, L. J. & El Haj, A. J., 1 Dec 2018, In : npj Regenerative Medicine. 3, 1, 9.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Translation of remote control regenerative technologies for bone repair

Markides, H., McLaren, J. S., Telling, N. D., Alom, N., Al-Mutheffer, E. A., Oreffo, R. O. C., Zannettino, A., Scammell, B. E., White, L. J. & El Haj, A. J., 2018, In : Regenerative Medicine. 3, p. 9

Research output: Contribution to journalArticle

Using genomics to better define high-risk MGUS/SMM patients

Dutta, A. K., Hewett, D. R., Fink, J. L. & Zannettino, A. C. W., 27 Nov 2018, In : Oncotarget. 9, 93, p. 36549-36550 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Zoledronate Enhances the Cytotoxicity of Gamma Delta T Cell Immunotherapy in an Orthotopic Mouse Model of Osteolytic Osteosarcoma

Zysk, A., Denichilo, M., Zinonos, I., Hay, S., Liapis, V., Ponomarev, V., Zannettino, A., Evdokiou, A. & Panagopoulos, V., 12 Sep 2018, In : Journal of Cancer Science & Therapy.

Research output: Contribution to journalArticle

2017

Adoptive transfer of ex vivo expanded Vγ9Vδ2 T cells in combination with zoledronic acid inhibits cancer growth and limits osteolysis in a murine model of osteolytic breast cancer

Zysk, A., DeNichilo, M. O., Panagopoulos, V., Zinonos, I., Liapis, V., Hay, S., Ingman, W., Ponomarev, V., Atkins, G., Findlay, D., Zannettino, A. & Evdokiou, A., 1 Feb 2017, In : Cancer Letters. 386, p. 141-150 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma

Liapis, V., Zysk, A., DeNichilo, M., Zinonos, I., Hay, S., Panagopoulos, V., Shoubridge, A., Difelice, C., Ponomarev, V., Ingman, W., Atkins, G. J., Findlay, D. M., Zannettino, A. C. W. & Evdokiou, A., 1 Sep 2017, In : Cancer Medicine. 6, 9, p. 2164-2176 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Bisphosphonate guidelines for treatment and prevention of myeloma bone disease

Lee, O. L., Horvath, N., Lee, C., Joshua, D., Ho, J., Szer, J., Quach, H., Spencer, A., Harrison, S., Mollee, P., Roberts, A. W., Talaulikar, D., Brown, R., Augustson, B., Ling, S., Jaksic, W., Gibson, J., Kalff, A., Johnston, A., Kalro, A. & 3 others, Ward, C., Prince, H. M. & Zannettino, A., 1 Aug 2017, In : Internal Medicine Journal. 47, 8, p. 938-951 14 p.

Research output: Contribution to journalLetter

9 Citations (Scopus)

Cutting edge genomics reveal new insights into tumour development, disease progression and therapeutic impacts in multiple myeloma

Dutta, A. K., Hewett, D. R., Fink, J. L., Grady, J. P. & Zannettino, A. C. W., 1 Jul 2017, In : British Journal of Haematology. 178, 2, p. 196-208 13 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)

DNA Barcoding Reveals Habitual Clonal Dominance of Myeloma Plasma Cells in the Bone Marrow Microenvironment

Hewett, D. R., Vandyke, K., Lawrence, D. M., Friend, N., Noll, J. E., Geoghegan, J. M., Croucher, P. I. & Zannettino, A., 1 Dec 2017, In : Neoplasia (United States). 19, 12, p. 972-981 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
5 Citations (Scopus)

EZH2 deletion in early mesenchyme compromises postnatal bone microarchitecture & structural integrity & accelerates remodeling

Hemming, S., Cakouros, D., Codrington, J., Vandyke, K., Arthur, A., Zannettino, A. & Gronthos, S., 1 Mar 2017, In : FASEB Journal. 31, 3, p. 1011-1027 17 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

HIF-2α promotes dissemination of plasma cells in multiple myeloma by regulating CXCL12/CXCR4 and CCR1

Vandyke, K., Zeissig, M. N., Hewett, D. R., Martin, S. K., Mrozik, K. M., Cheong, C. M., Diamond, P., To, L. B., Gronthos, S., Peet, D. J., Croucher, P. I. & Zannettino, A. C. W., 15 Oct 2017, In : Cancer Research. 77, 20, p. 5452-5463 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Histone deacetylases (HDAC) in physiological and pathological bone remodelling

Cantley, M. D., Zannettino, A. C. W., Bartold, P. M., Fairlie, D. P. & Haynes, D. R., 1 Feb 2017, In : Bone. 95, p. 162-174 13 p.

Research output: Contribution to journalReview article

19 Citations (Scopus)

mTORC1 plays an important role in skeletal development by controlling preosteoblast differentiation

Fitter, S., Matthews, M. P., Martin, S. K., Xie, J., Ooi, S. S., Walkley, C. R., Codrington, J. D., Ruegg, M. A., Hall, M. N., Proud, C. G., Gronthos, S. & Zannettino, A. C. W., 1 Jan 2017, In : Molecular and Cellular Biology. 37, 7, e00668-16.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Peroxidase enzymes inhibit osteoclast differentiation and bone resorption

Panagopoulos, V., Liapis, V., Zinonos, I., Hay, S., Leach, D. A., Ingman, W., DeNichilo, M. O., Atkins, G. J., Findlay, D. M., Zannettino, A. C. W. & Evdokiou, A., 15 Jan 2017, In : Molecular and Cellular Endocrinology. 440, p. 8-15 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress

Wallington-Beddoe, C. T., Bennett, M. K., Vandyke, K., Davies, L., Zebol, J. R., Moretti, P. A. B., Pitman, M. R., Hewett, D. R., Zannettino, A. C. W. & Pitson, S. M., 1 Jan 2017, In : Oncotarget. 8, 27, p. 43602-43616 15 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells

Vuckovic, S., Vandyke, K., Rickards, D. A., Mccauley Winter, P., Brown, S. H. J., Mitchell, T. W., Liu, J., Lu, J., Askenase, P. W., Yuriev, E., Capuano, B., Ramsland, P. A., Hill, G. R., Zannettino, A. C. W. & Hutchinson, A. T., 1 May 2017, In : British Journal of Haematology. 177, 3, p. 423-440 18 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The Mesenchymal Precursor Cell Marker Antibody STRO-1 Binds to Cell Surface Heat Shock Cognate 70

Fitter, S., Gronthos, S., Ooi, S. S. & Zannettino, A. C. W., 1 Apr 2017, In : Stem Cells. 35, 4, p. 940-951 12 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Treatment of patients with Waldenström macroglobulinaemia: clinical practice guidelines from the Myeloma Foundation of Australia Medical and Scientific Advisory Group

Talaulikar, D., Tam, C. S., Joshua, D., Ho, J. P., Szer, J., Quach, H., Spencer, A., Harrison, S., Mollee, P., Roberts, A. W., Horvath, N., Lee, C., Zannettino, A., Brown, R., Augustson, B., Jaksic, W., Gibson, J., Kalff, A., Johnston, A., Trotman, J. & 4 others, Kalro, A., Grigoriadis, G., Ward, C. & Prince, H. M., 1 Jan 2017, In : Internal Medicine Journal. 47, 1, p. 35-49 15 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Tyrosine kinase receptor c-ros-oncogene 1 mediates TWIST-1 regulation of human mesenchymal stem cell lineage commitment

Camp, E., Anderson, P. J., Zannettino, A. C. W. & Gronthos, S., 1 Jan 2017, In : Bone. 94, p. 98-107 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2016

Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance

Walia, M. K., Ho, P. M. W., Taylor, S., Ng, A. J. M., Gupte, A., Chalk, A. M., Zannettino, A. C. W., Martin, T. J. & Walkley, C. R., 12 Apr 2016, In : eLife. 5, April 2016, e13446.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Allogeneic Mesenchymal Precursor Cells Promote Healing in Postero-lateral Annular Lesions and Improve Indices of Lumbar Intervertebral Disc Degeneration in an Ovine Model

Freeman, B. J. C., Kuliwaba, J. S., Jones, C. F., Shu, C. C., Colloca, C. J., Zarrinkalam, M. R., Mulaibrahimovic, A., Gronthos, S., Zannettino, A. C. W. & Howell, S., 1 Sep 2016, In : Spine. 41, 17, p. 1331-1339 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis

Ebert, L. M., Tan, L. Y., Johan, M. Z., Min, K. K. M., Cockshell, M. P., Parham, K. A., Betterman, K. L., Szeto, P., Boyle, S., Silva, L., Peng, A., Zhang, Y. F., Ruszkiewicz, A., Zannettino, A. C. W., Gronthos, S., Koblar, S., Harvey, N. L., Lopez, A. F., Shackleton, M. & Bonder, C. S., 1 Oct 2016, In : Angiogenesis. 19, 4, p. 463-486 24 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Anticancer efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in osteolytic breast cancer murine models

Liapis, V., Zinonos, I., Labrinidis, A., Hay, S., Ponomarev, V., Panagopoulos, V., Zysk, A., Denichilo, M., Ingman, W., Atkins, G. J., Findlay, D. M., Zannettino, A. C. W. & Evdokiou, A., 1 Mar 2016, In : Cancer Medicine. 5, 3, p. 534-545 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Engineering DN hydrogels from regenerated silk fibroin and poly(: N -vinylcaprolactam)

Whittaker, J. L., Dutta, N. K., Zannettino, A. & Choudhury, N. R., 1 Jan 2016, In : Journal of Materials Chemistry B. 4, 33, p. 5519-5533 15 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Identification of novel EZH2 targets regulating osteogenic differentiation in mesenchymal stem cells

Hemming, S., Cakouros, D., Vandyke, K., Davis, M. J., Zannettino, A. C. W. & Gronthos, S., 15 Jun 2016, In : Stem Cells and Development. 25, 12, p. 909-921 13 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)