Adeline Bowen

Dr Adeline Lau joined the Childhood Dementia Research group in the Hopwood Centre for Neurobiology (formerly the Lysosomal Diseases Research Unit) in 2001. She was awarded an NHMRC Biomedical (Dora Lush) Postgraduate Research Scholarship to examine the clinical efficacy of a gene therapy approach for mucopolysaccharidosis type IIIA (MPS IIIA), a neurological lysosomal storage disorder, under the supervision of A. Prof. Kim Hemsley and Em. Prof. John Hopwood. As part of these studies, she was a visiting scientist at the Institut de Génétique Moléculaire de Montpellier (France) in the laboratory of Dr Eric Kremer. Adeline’s research has evaluated therapies such as bone marrow transplantation, stem cell therapy, non-human adenoviral and AAV gene transfer and small molecule drugs. She also has an interest in understanding how the pathology develops and in characterising the clinical phenotype of this disease in mammalian and invertebrate animal models.

• Neurological disorders
• Behavioural phenotyping
• Gene therapy
• Small molecule drugs