Adeline Bowen

Dr Adeline Lau joined the Childhood Dementia Research group (formerly the CNS Therapeutics Section) in the Hopwood Centre for Neurobiology (formerly the Lysosomal Diseases Research Unit) in 2001. She was awarded an NHMRC Biomedical (Dora Lush) Postgraduate Research Scholarship to examine the clinical efficacy of a gene therapy approach for mucopolysaccharidosis type IIIA (MPS IIIA), a neurological lysosomal storage disorder, under the supervision of Dr Kim Hemsley and Professor John Hopwood. As part of these studies, she was a visiting scientist at the Institut de Génétique Moléculaire de Montpellier in France, where she generated gene transfer vectors in the laboratory of Dr Eric Kremer. Adeline’s research has focused on evaluating novel, long-term therapies for children affected by MPS IIIA, and understanding how pathology develops in this disorder to make treatments more effective. 

• Neurological disorders
• Behavioural phenotyping
• Viral vectors
• Bone marrow transplantation
• Brain-directed therapies