Precision Medicine

Research Output 1987 2019

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2014
9 Citations (Scopus)

Study of alveolar rhabdomyosarcoma copy number alterations by single nucleotide polymorphism analysis

Lynn, M., Shah, N., Conroy, J., Ennis, S., Morris, T., Betts, D. & O'Sullivan, M., 2014, In : Applied Immunohistochemistry and Molecular Morphology. 22, 3, p. 213-221 9 p.

Research output: Contribution to journal › Article

20 Citations (Scopus)

Suppression of the auxin response pathway enhances susceptibility to Phytophthora cinnamomi while phosphite-mediated resistance stimulates the auxin signalling pathway

Eshraghi, L., Anderson, J. P., Aryamanesh, N., McComb, J. A., Shearer, B. & Hardy, G. S. J. E., 20 Mar 2014, In : BMC Plant Biology. 14, 1, 68.

Research output: Contribution to journal › Article

7 Citations (Scopus)

Sustainable remediation: Electrochemically assisted microbial dechlorination of tetrachloroethene-contaminated groundwater

Patil, S. S., Adetutu, E., Rochow, J., Mitchell, J. G. & Ball, A. S., 1 Jan 2014, In : Microbial Biotechnology. 7, 1, p. 54-63 10 p.

Research output: Contribution to journal › Article

9 Citations (Scopus)

Symptoms of depression and rates of neurocognitive impairment in HIV positive patients in Beijing, China

Dwyer, R., Wenhui, L., Cysique, L., Brew, B. J., Lal, L., Bain, P., Wesselingh, S. & Wright, E. J., 20 Jun 2014, In : Journal of Affective Disorders. 162, p. 89-95 7 p.

Research output: Contribution to journal › Article

502 Citations (Scopus)

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

Roberts, K. G., Li, Y., Payne-Turner, D., Harvey, R. C., Yang, Y. L., Pei, D., McCastlain, K., Ding, L., Lu, C., Song, G., Ma, J., Becksfort, J., Rusch, M., Chen, S. C., Easton, J., Cheng, J., Boggs, K., Santiago-Morales, N., Iacobucci, I., Fulton, R. S. & 54 othersWen, J., Valentine, M., Cheng, C., Paugh, S. W., Devidas, M., Chen, I. M., Reshmi, S., Smith, A., Hedlund, E., Gupta, P., Nagahawatte, P., Wu, G., Chen, X., Yergeau, D., Vadodaria, B., Mulder, H., Winick, N. J., Larsen, E. C., Carroll, W. L., Heerema, N. A., Carroll, A. J., Grayson, G., Tasian, S. K., Moore, A. S., Keller, F., Frei-Jones, M., Whitlock, J. A., Raetz, E. A., White, D. L., Hughes, T. P., Guidry Auvil, J. M., Smith, M. A., Marcucci, G., Bloomfield, C. D., Mrózek, K., Kohlschmidt, J., Stock, W., Kornblau, S. M., Konopleva, M., Paietta, E., Pui, C. H., Jeha, S., Relling, M. V., Evans, W. E., Gerhard, D. S., Gastier-Foster, J. M., Mardis, E., Wilson, R. K., Loh, M. L., Downing, J. R., Hunger, S. P., Willman, C. L., Zhang, J. & Mullighan, C. G., 11 Sep 2014, In : New England Journal of Medicine. 371, 11, p. 1005-1015 11 p.

Research output: Contribution to journal › Article

23 Citations (Scopus)

The CIMP phenotype in BRAF mutant serrated polyps from a prospective colonoscopy patient cohort

Fernando, W. C., Miranda, M. S., Worthley, D. L., Togashi, K., Watters, D. J., Leggett, B. A. & Spring, K. J., 2014, In : Gastroenterology Research and Practice. 2014, 374926.

Research output: Contribution to journal › Article

66 Citations (Scopus)

The effect of long-term macrolide treatment on respiratory microbiota composition in non-cystic fibrosis bronchiectasis: An analysis from the randomised, double-blind, placebo-controlled BLESS trial

Rogers, G. B., Bruce, K. D., Martin, M. L., Burr, L. D. & Serisier, D. J., 1 Jan 2014, In : The Lancet Respiratory Medicine. 2, 12, p. 988-996 9 p.

Research output: Contribution to journal › Article

37 Citations (Scopus)

The effects of probiotic bacteria on glycaemic control in overweight men and women: A randomised controlled trial

Ivey, K. L., Hodgson, J. M., Kerr, D. A., Lewis, J. R., Thompson, P. L. & Prince, R. L., 1 Jan 2014, In : European Journal of Clinical Nutrition. 68, 4, p. 447-452 6 p.

Research output: Contribution to journal › Article

21 Citations (Scopus)

The miRNAome of the postpartum dairy cow liver in negative energy balance

Fatima, A., Lynn, D. J., O'Boyle, P., Seoighe, C. & Morris, D., 12 Apr 2014, In : BMC Genomics. 15, 1, 279.

Research output: Contribution to journal › Article

80 Citations (Scopus)

The Opisthorchis viverrini genome provides insights into life in the bile duct

Young, N. D., Nagarajan, N., Lin, S. J., Korhonen, P. K., Jex, A. R., Hall, R. S., Safavi-Hemami, H., Kaewkong, W., Bertrand, D., Gao, S., Seet, Q., Wongkham, S., Teh, B. T., Wongkham, C., Intapan, P. M., Maleewong, W., Yang, X., Hu, M., Wang, Z., Hofmann, A. & 4 othersSternberg, P. W., Tan, P., Wang, J. & Gasser, R. B., 9 Jul 2014, In : Nature communications. 5, 4378.

Research output: Contribution to journal › Article

20 Citations (Scopus)

Time between collection and storage significantly influences bacterial sequence composition in sputum samples from cystic fibrosis respiratory infections

Cuthbertson, L., Rogers, G. B., Walker, A. W., Oliver, A., Hafiz, T., Hoffman, L. R., Carroll, M. P., Parkhill, J., Bruce, K. D. & Van Der Gast, C. J., 1 Jan 2014, In : Journal of Clinical Microbiology. 52, 8, p. 3011-3016 6 p.

Research output: Contribution to journal › Article

11 Citations (Scopus)

Trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells

Watanabe, Y., Onodera, A., Kanai, U., Ichikawa, T., Obata-Ninomiya, K., Wada, T., Kiuchi, M., Iwamura, C., Tumes, D., Shinoda, K., Yagi, R., Motohashi, S., Hirahara, K. & Nakayama, T., 2 Sep 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 35, p. 12829-12834 6 p.

Research output: Contribution to journal › Article

15 Citations (Scopus)

Use of variogram analysis to classify field peas with and without internal defects caused by weevil infestation

Nansen, C., Zhang, X., Aryamanesh, N. & Yan, G., 1 Jan 2014, In : Journal of Food Engineering. 123, p. 17-22 6 p.

Research output: Contribution to journal › Article

Validation of Nanostring Microrna Analysis in Leukaemic Blood

Gordon, J., Bailey, C., Ritchie, W., Watkins, D. B., Gray (leclercq), T., White, D., Hughes, T. & Rasko, J. E. J., 2014, In : Pathology.

Research output: Contribution to journal › Article

2013
12 Citations (Scopus)

Accumulation of effector memory CD8+ T cells in nasal polyps

Pant, H., Hughes, A., Miljkovic, D., Schembri, M., Wormald, P., Macardle, P., Grose, R., Zola, H. & Krumbiegel, D., Sep 2013, In : American Journal of Rhinology and Allergy. 27, 5

Research output: Contribution to journal › Article

28 Citations (Scopus)

A genome-wide association study for somatic cell score using the Illumina high-density bovine beadchip identifies several novel QTL potentially related to mastitis susceptibility

Meredith, B. K., Berry, D. P., Kearney, F., Finlay, E. K., Fahey, A. G., Bradley, D. G. & Lynn, D., 18 Dec 2013, In : Frontiers in Genetics. 4, NOV, Article 229.

Research output: Contribution to journal › Article

66 Citations (Scopus)

An injectable hydrogel incorporating mesenchymal precursor cells and pentosan polysulphate for intervertebral disc regeneration

Frith, J. E., Cameron, A. R., Menzies, D. J., Ghosh, P., Whitehead, D. L., Gronthos, S., Zannettino, A. C. W. & Cooper-White, J. J., 1 Jan 2013, In : Biomaterials. 34, 37, p. 9430-9440 11 p.

Research output: Contribution to journal › Article

511 Citations (Scopus)

A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias

Cortes, J. E., Kim, D. W., Pinilla-Ibarz, J., Le Coutre, P., Paquette, R., Chuah, C., Nicolini, F. E., Apperley, J. F., Khoury, H. J., Talpaz, M., DiPersio, J., DeAngelo, D. J., Abruzzese, E., Rea, D., Baccarani, M., Müller, M. C., Gambacorti-Passerini, C., Wong, S., Lustgarten, S., Rivera, V. M. & 10 othersClackson, T., Turner, C. D., Haluska, F. G., Guilhot, F., Deininger, M. W., Hochhaus, A., Hughes, T., Goldman, J. M., Shah, N. P. & Kantarjian, H., 1 Jan 2013, In : New England Journal of Medicine. 369, 19, p. 1783-1796 14 p.

Research output: Contribution to journal › Article

10 Citations (Scopus)

A polyphasic approach for assessing the suitability of bioremediation for the treatment of hydrocarbon-impacted soil

Adetutu, E. M., Smith, R. J., Weber, J., Aleer, S., Mitchell, J. G., Ball, A. S. & Juhasz, A. L., 5 Apr 2013, In : Science of the Total Environment. p. 51-58 8 p.

Research output: Contribution to journal › Article

10 Citations (Scopus)

A relationship between Pseudomonal growth behaviour and cystic fibrosis patient lung function identified in a metabolomic investigation

Kozlowska, J., Rivett, D. W., Vermeer, L. S., Carroll, M. P., Bruce, K. D., James Mason, A. & Rogers, G. B., 1 Dec 2013, In : Metabolomics. 9, 6, p. 1262-1273 12 p.

Research output: Contribution to journal › Article

18 Citations (Scopus)

Ascitic Microbiota Composition Is Correlated with Clinical Severity in Cirrhosis with Portal Hypertension

Rogers, G. B., van der Gast, C. J., Bruce, K. D., Marsh, P., Collins, J. E., Sutton, J. & Wright, M., 25 Sep 2013, In : PLoS ONE. 8, 9, e74884.

Research output: Contribution to journal › Article

9 Citations (Scopus)

Assessing impediments to hydrocarbon biodegradation in weathered contaminated soils

Adetutu, E., Weber, J., Aleer, S., Dandie, C. E., Aburto-Medina, A., Ball, A. S. & Juhasz, A. L., 5 Oct 2013, In : Journal of Hazardous Materials. p. 847-853 7 p.

Research output: Contribution to journal › Article

65 Citations (Scopus)

Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy

Angelini, S., Soverini, S., Ravegnini, G., Barnett, M., Turrini, E., Thornquist, M., Pane, F., Hughes, T. P., White, D. L., Radich, J., Kim, D. W., Saglio, G., Cilloni, D., Iacobucci, I., Perini, G., Woodman, R., Cantelli-Forti, G., Baccarani, M., Hrelia, P. & Martinelli, G., 1 Feb 2013, In : Haematologica. 98, 2, p. 193-200 8 p.

Research output: Contribution to journal › Article

15 Citations (Scopus)

Associations and interactions between lipid profiles, retinopathy and nephropathy in patients with type 1 diabetes: The FinnDiane study

Tolonen, N., Hietala, K., Forsblom, C., Harjutsalo, V., Mäkinen, V. P., Kytö, J., Summanen, P. A., Thorn, L. M., Wadén, J., Gordin, D., Taskinen, M. R. & Groop, P. H., 1 Nov 2013, In : Journal of Internal Medicine. 274, 5, p. 469-479 11 p.

Research output: Contribution to journal › Article

14 Citations (Scopus)

BCR-ABL1 kinase domain mutations may persist at very low levels for many years and lead to subsequent TKI resistance

Parker, W. T., Yeoman, A. L., Jamison, B. A., Yeung, D. T., Scott, H. S., Hughes, T. P. & Branford, S., 17 Sep 2013, In : British Journal of Cancer. 109, 6, p. 1593-1598 6 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

Cardiac magnetic resonance, transthoracic and transoesophageal echocardiography: A comparison of in vivo assessment of ventricular function in rats

Richardson, J. D., Bertaso, A. G., Frost, L., Psaltis, P. J., Carbone, A., Koschade, B., Wong, D. T., Nelson, A. J., Paton, S., Williams, K., Azarisman, S., Worthley, M. I., Teo, K. S., Gronthos, S., Zannettino, A. C. W. & Worthley, S. G., 2013, In : Laboratory Animals. 47, 4, p. 291-300 10 p.

Research output: Contribution to journal › Article

17 Citations (Scopus)

Carrier mounted bacterial consortium facilitates oil remediation in the marine environment

Simons, K. L., Sheppard, P. J., Adetutu, E. M., Kadali, K., Juhasz, A. L., Manefield, M., Sarma, P. M., Lal, B. & Ball, A. S., 2013, In : Bioresource Technology. p. 107-116 10 p.

Research output: Contribution to journal › Article

12 Citations (Scopus)

Characterization of the prostate cancer susceptibility gene KLF6 in human and mouse prostate cancers

Chiam, K., Ryan, N. K., Ricciardelli, C., Day, T. K., Buchanan, G., Ochnik, A. M., Murti, K., Selth, L. A., Butler, L. M., Tilley, W. D. & Bianco-Miotto, T., Jan 2013, In : Prostate. 73, 2, p. 182-193 12 p.

Research output: Contribution to journal › Article

36 Citations (Scopus)

Chromosome 2q31. 1 associates with ESRD in women with type 1 diabetes

Sandholm, N., McKnight, A. J., Salem, R. M., Brennan, E. P., Forsblom, C., Harjutsalo, V., Mäkinen, V. P., McKay, G. J., Sadlier, D. M., Williams, W. W., Martin, F., Panduru, N. M., Tarnow, L., Tuomilehto, J., Tryggvason, K., Zerbini, G., Comeau, M. E., Langefeld, C. D., Godson, C., Hirschhorn, J. N. & 3 othersMaxwell, A. P., Florez, J. C. & Groop, P. H., Oct 2013, In : Journal of the American Society of Nephrology. 24, 10, p. 1537-1543 7 p.

Research output: Contribution to journal › Article

83 Citations (Scopus)

Circulating microRNAs predict biochemical recurrence in prostate cancer patients

Selth, L. A., Townley, S. L., Bert, A. G., Stricker, P. D., Sutherland, P. D., Horvath, L. G., Goodall, G. J., Butler, L. M. & Tilley, W. D., 6 Aug 2013, In : British Journal of Cancer. 109, 3, p. 641-650 10 p.

Research output: Contribution to journal › Article

9 Citations (Scopus)

Circulating N-cadherin levels are a negative prognostic indicator in patients with multiple myeloma

Vandyke, K., Chow, A. W. S., Williams, S. A., To, L. B. & Zannettino, A. C. W., 1 May 2013, In : British Journal of Haematology. 161, 4, p. 499-507 9 p.

Research output: Contribution to journal › Article

97 Citations (Scopus)

Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition

Rogers, G. B., Van Der Gast, C. J., Cuthbertson, L., Thomson, S. K., Bruce, K. D., Martin, M. L. & Serisier, D. J., 10 Apr 2013, In : Thorax. 68, 8, p. 731-737 7 p.

Research output: Contribution to journal › Article

18 Citations (Scopus)

Complexity, temporal stability, and clinical correlates of airway bacterial community composition in primary ciliary Dyskinesia

Rogers, G. B., Carroll, M. P., Zain, N. M. M., Bruce, K. D., Lock, K., Walker, W., Jones, G., Daniels, T. W. V. & Lucas, J. S., 1 Dec 2013, In : Journal of Clinical Microbiology. 51, 12, p. 4029-4035 7 p.

Research output: Contribution to journal › Article

14 Citations (Scopus)

Counter-regulation of alpha- and beta-synuclein expression at the transcriptional level

Wright, J., McHugh, P. C., Pan, S., Cunningham, A. & Brown, D. R., 1 Nov 2013, In : Molecular and Cellular Neuroscience. 57, p. 33-41 9 p.

Research output: Contribution to journal › Article

8 Citations (Scopus)

Dasatinib targets chronic myeloid leukemia-CD34+ progenitors as effectively as it targets mature cells

Hiwase, D. K., Saunders, V. A., Nievergall, E., Ross, D. D., White, D. L. & Hughes, T. P., 2013, In : Haematologica. 98, 6, p. 896-900 5 p.

Research output: Contribution to journal › Article

13 Citations (Scopus)

Degree of kinase inhibition achieved in vitro by imatinib and nilotinib is decreased by high levels of ABCB1 but not ABCG2

Eadie, L. N., Saunders, V. A., Hughes, T. P. & White, D. L., 1 Mar 2013, In : Leukemia and Lymphoma. 54, 3, p. 569-578 10 p.

Research output: Contribution to journal › Article

11 Citations (Scopus)

Determining the metabolic footprints of hydrocarbon degradation using multivariate analysis

Smith, R. J., Jeffries, T. C., Adetutu, E. M., Fairweather, P. G. & Mitchell, J. G., 25 Nov 2013, In : PLoS ONE. 8, 11

Research output: Contribution to journal › Article

Open Access
19 Citations (Scopus)

Differential quantitative proteomic profiling of Leishmania infantum and Leishmania mexicana density gradient separated membranous fractions

Lynn, M. A., Marr, A. K. & McMaster, W. R., 6 Apr 2013, In : Journal of Proteomics. 82, p. 179-192 14 p.

Research output: Contribution to journal › Article

Does anaerobic bacterial antibiosis decrease fungal diversity in oral necrobacillosis disease?

Antiabong, J. F., Boardman, W., Adetutu, E. M., Brown, M. H. & Ball, A. S., Dec 2013, In : Research in Veterinary Science. p. 1012-1020 9 p.

Research output: Contribution to journal › Article

79 Citations (Scopus)

Early molecular response and female sex strongly predict stable undetectable BCR-ABL1, the criteria for imatinib discontinuation in patients with CML

Branford, S., Yeung, D. T., Ross, D. M., Prime, J. A., Field, C. R., Altamura, H. K., Yeoman, A. L., Georgievski, J., Jamison, B. A., Phillis, S., Sullivan, B., Briggs, N. E., Hertzberg, M., Seymour, J. F., Reynolds, J. & Hughes, T. P., 9 May 2013, In : Blood. 121, 19, p. 3818-3824 7 p.

Research output: Contribution to journal › Article

26 Citations (Scopus)

EphB4 enhances the process of endochondral ossification and inhibits remodeling during bone fracture repair

Arthur, A., Panagopoulos, R. A., Cooper, L., Menicanin, D., Parkinson, I. H., Codrington, J. D., Vandyke, K., Zannettino, A. C. W., Koblar, S. A., Sims, N. A., Matsuo, K. & Gronthos, S., 1 Apr 2013, In : Journal of Bone and Mineral Research. 28, 4, p. 926-935 10 p.

Research output: Contribution to journal › Article

35 Citations (Scopus)

EphB and ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells

Nguyen, T. M., Arthur, A., Hayball, J. D. & Gronthos, S., 15 Oct 2013, In : Stem Cells and Development. 22, 20, p. 2751-2764 14 p.

Research output: Contribution to journal › Article

33 Citations (Scopus)

Establishment and validation of analytical reference panels for the standardization of quantitative BCR-ABL1 measurements on the international scale

White, H. E., Hedges, J., Bendit, I., Branford, S., Colomer, D., Hochhaus, A., Hughes, T., Kamel-Reid, S., Kim, D. W., Modur, V., Müller, M. C., Pagnano, K. B., Pane, F., Radich, J., Cross, N. C. P. & Labourier, E., 1 Jun 2013, In : Clinical Chemistry. 59, 6, p. 938-948 11 p.

Research output: Contribution to journal › Article

19 Citations (Scopus)

Expression of the murine transcription factor SOX3 during embryonic and adult neurogenesis

Rogers, N., Cheah, P. S., Szarek, E., Banerjee, K., Schwartz, J. & Thomas, P., 4 Jun 2013, In : Gene Expression Patterns. 13, 7, p. 240-248 9 p.

Research output: Contribution to journal › Article

5 Citations (Scopus)

Expression of VEGF-A, otx homeobox and p53 family genes in proliferative vitreoretinopathy

Azzolini, C., Pagani, I., Pirrone, C., Borroni, D., Donati, S., Al Oum, M., Pigni, D., Chiaravalli, A. M., Vinciguerra, R., Simonelli, F. & Porta, G., 1 Jan 2013, In : Mediators of Inflammation. 2013, 857380.

Research output: Contribution to journal › Article

8 Citations (Scopus)

High Yield Production of a Soluble Human Interleukin-3 Variant from E. coli with Wild-Type Bioactivity and Improved Radiolabeling Properties

Hercus, T. R., Barry, E. F., Dottore, M., McClure, B. J., Webb, A. I., Lopez, A. F., Young, I. G. & Murphy, J. M., 26 Aug 2013, In : PLoS ONE. 8, 8, e74376.

Research output: Contribution to journal › Article

29 Citations (Scopus)

HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia

Brumatti, G., Salmanidis, M., Kok, C. H., Bilardi, R. A., Sandow, J. J., Silke, N., Mason, K., Visser, J., Jabbour, A. M., Glaser, S. P., Okamoto, T., Bouillet, P., D'Andrea, R. J. & Ekert, P. G., 1 Jan 2013, In : Oncotarget. 4, 11, p. 1933-1947 15 p.

Research output: Contribution to journal › Article

11 Citations (Scopus)

Identification of Shared Genes and Pathways: A Comparative Study of Multiple Sclerosis Susceptibility, Severity and Response to Interferon Beta Treatment

Mahurkar, S., Moldovan, M., Suppiah, V. & O'Doherty, C., 28 Feb 2013, In : PLoS ONE. 8, 2, e57655.

Research output: Contribution to journal › Article

14 Citations (Scopus)

Identifying conserved protein complexes between species by constructing interolog networks

Nguyen, P. V., Srihari, S. & Leong, H. W., 22 Oct 2013, In : BMC Bioinformatics. 14, SUPPL16, S8.

Research output: Contribution to journal › Article

36 Citations (Scopus)

Impact of antibiotic treatment for pulmonary exacerbations on bacterial diversity in cystic fibrosis

Daniels, T. W. V., Rogers, G. B., Stressmann, F. A., van der Gast, C. J., Bruce, K. D., Jones, G. R., Connett, G. J., Legg, J. P. & Carroll, M. P., 1 Jan 2013, In : Journal of Cystic Fibrosis. 12, 1, p. 22-28 7 p.

Research output: Contribution to journal › Article