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2017
9 Citations (Scopus)

The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells

Vuckovic, S., Vandyke, K., Rickards, D. A., Mccauley Winter, P., Brown, S. H. J., Mitchell, T. W., Liu, J., Lu, J., Askenase, P. W., Yuriev, E., Capuano, B., Ramsland, P. A., Hill, G. R., Zannettino, A. C. W. & Hutchinson, A. T., 1 May 2017, In : British Journal of Haematology. 177, 3, p. 423-440 18 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
13 Citations (Scopus)

The combination of metformin and valproic acid induces synergistic apoptosis in the presence of p53 and androgen signaling in prostate cancer

Tran, L. N. K., Kichenadasse, G., Butler, L. M., Centenera, M. M., Morel, K. L., Ormsby, R. J., Michael, M. Z., Lower, K. M. & Sykes, P. J., 1 Dec 2017, In : Molecular Cancer Therapeutics. 16, 12, p. 2689-2700 12 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

The diverse metabolic roles of peripheral serotonin

Martin, A. M., Young, R. L., Leong, L., Rogers, G. B., Spencer, N. J., Jessup, C. F. & Keating, D. J., 1 Mar 2017, In : Endocrinology.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The G-protein coupled receptor 56, expressed in colonic stem and cancer cells, binds progastrin to promote proliferation and carcinogenesis

Jin, G., Sakitani, K., Wang, H., Jin, Y., Dubeykovskiy, A., Worthley, D. L., Tailor, Y. & Wang, T. C., 1 Jan 2017, In : Oncotarget. 8, 25, p. 40606-40619 14 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

The incidence and natural history of dasatinib complications in the treatment of chronic myeloid leukemia

Fox, L. C., Cummins, K. D., Costello, B., Yeung, D., Cleary, R., Forsyth, C., Tatarczuch, M., Burbury, K., Motorna, O., Shortt, J., Fleming, S., McQuillan, A., Schwarer, A., Harrup, R., Holmes, A., Ratnasingam, S., Chan, K. L., Hsu, W. H., Ashraf, A., Putt, F. & 1 othersGrigg, A., 23 May 2017, In : Blood Advances. 1, 13, p. 802-811 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The Mesenchymal Precursor Cell Marker Antibody STRO-1 Binds to Cell Surface Heat Shock Cognate 70

Fitter, S., Gronthos, S., Ooi, S. S. & Zannettino, A. C. W., 1 Apr 2017, In : Stem Cells. 35, 4, p. 940-951 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The pentatricopeptide repeat protein EMB2654 is essential for trans-splicing of a chloroplast small ribosomal subunit transcript

Aryamanesh, N., Ruwe, H., Sanglard, L. V. P., Eshraghi, L., Bussell, J. D., Howell, K. A., Small, I. & des Francs-Small, C. C., 1 Feb 2017, In : Plant Physiology. 173, 2, p. 1164-1176 13 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The potential of the microbiota to influence vaccine responses

Lynn, D. J. & Pulendran, B., 1 Sep 2017, In : Journal of Leukocyte Biology. 103, 2, p. 225-231 7 p., 28864446 .

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)

Transcriptome profiling of IL-17A preactivated mesenchymal stem cells: A comparative study to unmodified and IFN- γ modified mesenchymal stem cells

Sivanathan, K. N., Rojas-Canales, D., Grey, S. T., Gronthos, S. & Coates, P. T., 1 Jan 2017, In : Stem Cells International. 2017, 1025820.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Treatment-free remission following frontline nilotinib in patients with chronic myeloid leukemia in chronic phase: Results from the ENESTfreedom study

Hochhaus, A., Masszi, T., Giles, F. J., Radich, J. P., Ross, D., Gómez Casares, M. T., Hellmann, A., Stentoft, J., Conneally, E., García-Gutiérrez, V., Gattermann, N., Wiktor-Jedrzejczak, W., Le Coutre, P. D., Martino, B., Saussele, S., Menssen, H. D., Deng, W., Krunic, N., Bedoucha, V. & Saglio, G., 1 Jul 2017, In : Leukemia. 31, 7, p. 1525-1531 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Treatment of patients with Waldenström macroglobulinaemia: clinical practice guidelines from the Myeloma Foundation of Australia Medical and Scientific Advisory Group

Talaulikar, D., Tam, C. S., Joshua, D., Ho, J. P., Szer, J., Quach, H., Spencer, A., Harrison, S., Mollee, P., Roberts, A. W., Horvath, N., Lee, C., Zannettino, A., Brown, R., Augustson, B., Jaksic, W., Gibson, J., Kalff, A., Johnston, A., Trotman, J. & 4 othersKalro, A., Grigoriadis, G., Ward, C. & Prince, H. M., 1 Jan 2017, In : Internal Medicine Journal. 47, 1, p. 35-49 15 p.

Research output: Contribution to journalArticle

144 Citations (Scopus)

Tumour-associated and non-tumour-associated microbiota in colorectal cancer

Flemer, B., Lynch, D. B., Brown, J. M. R., Jeffery, I. B., Ryan, F., Claesson, M. J., O'Riordain, M., Shanahan, F. & O'Toole, P. W., 1 Apr 2017, In : Gut. 66, 4, p. 633-643 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Two isoforms of Clp peptidase in Pseudomonas aeruginosa control distinct aspects of cellular physiology

Hall, B. M., Breidenstein, E. B. M., de la Fuente-Núñez, C., Reffuveille, F., Mawla, G. D., Hancock, R. & Baker, T. A., 1 Jan 2017, In : Journal of bacteriology. 199, 3, e00568-16.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Tyrosine kinase receptor c-ros-oncogene 1 mediates TWIST-1 regulation of human mesenchymal stem cell lineage commitment

Camp, E., Anderson, P. J., Zannettino, A. C. W. & Gronthos, S., 1 Jan 2017, In : Bone. 94, p. 98-107 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Using the contextual hub analysis tool (CHAT) in cytoscape to identify contextually relevant network hubs

Muetze, T. & Lynn, D. J., 2017, In : Current Protocols in Bioinformatics. 2017, p. 8.24.1-8.24.13 8 p., 10.1002/cpbi.35.

Research output: Contribution to journalArticle

Open Access
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5 Citations (Scopus)

Versatile single-step-assembly CRISPR/Cas9 vectors for dual gRNA expression

Adikusuma, F., Pfitzner, C. & Thomas, P., 1 Dec 2017, In : PloS one. 12, 12, e0187236.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Viperin is an important host restriction factor in control of Zika virus infection

Van Der Hoek, K. H., Eyre, N. S., Shue, B., Khantisitthiporn, O., Glab-Ampi, K., Carr, J. M., Gartner, M. J., Jolly, L. A., Thomas, P., Adikusuma, F., Jankovic-Karasoulos, T., Roberts, C. T., Helbig, K. J. & Beard, M. R., 1 Dec 2017, In : Scientific Reports. 7, 1, 4138.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Whole exome sequencing implicates eye development, the unfolded protein response and plasma membrane homeostasis in primary open-angle glaucoma

Zhou, T., Souzeau, E., Sharma, S., Landers, J., Mills, R., Goldberg, I., Healey, P. R., Graham, S., Hewitt, A. W., Mackey, D. A., Galanopoulos, A., Casson, R. J., Ruddle, J. B., Ellis, J., Leo, P., Brown, M. A., MacGregor, S., Lynn, D. J., Burdon, K. P. & Craig, J. E., 1 Mar 2017, In : PloS one. 12, 3, e0172427.

Research output: Contribution to journalArticle

Yeast RNA extract suppresses human osteoclast resorption in vitro

Cantley, M., Rainsford, K. D. & Haynes, D. R., 1 Oct 2017, In : Inflammopharmacology. 25, 5, p. 571-576 6 p.

Research output: Contribution to journalArticle

2016
16 Citations (Scopus)
21 Citations (Scopus)

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors

Smith, A. M., Dun, M. D., Lee, E. M., Harrison, C., Kahl, R., Flanagan, H., Panicker, N., Mashkani, B., Don, A. S., Morris, J., Toop, H., Lock, R. B., Powell, J. A., Thomas, D., Guthridge, M. A., Moore, A., Ashman, L. K., Skelding, K. A., Enjeti, A. & Verrills, N. M., 1 Jan 2016, In : Oncotarget. 7, 30, p. 47465-47478 14 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance

Walia, M. K., Ho, P. M. W., Taylor, S., Ng, A. J. M., Gupte, A., Chalk, A. M., Zannettino, A. C. W., Martin, T. J. & Walkley, C. R., 12 Apr 2016, In : eLife. 5, April 2016, e13446.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Acute sensitivity of Ph-like acute lymphoblastic leukemia to the SMAC-mimetic birinapant

Richmond, J., Robbins, A., Evans, K., Beck, D., Kurmasheva, R. T., Billups, C. A., Carol, H., Heatley, S., Sutton, R., Marshall, G. M., White, D., Pimanda, J., Houghton, P. J., Smith, M. A. & Lock, R. B., 1 Aug 2016, In : Cancer Research. 76, 15, p. 4579-4591 13 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

A genome-wide association study for genetic susceptibility to Mycobacterium bovis infection in dairy cattle identifies a susceptibility QTL on chromosome 23

Richardson, I. W., Berry, D. P., Wiencko, H. L., Higgins, I. M., More, S. J., McClure, J., Lynn, D. & Bradley, D. G., 9 Mar 2016, In : Genetics Selection Evolution. 48, 1, 197.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Agonistic CD40 mAb-driven IL12 reverses resistance to anti-PD1 in a T-cell-rich tumor

Ngiow, S. F., Young, A., Blake, S. J., Hill, G. R., Yagita, H., Teng, M. W. L., Korman, A. J. & Smyth, M. J., 1 Nov 2016, In : Cancer Research. 76, 21, p. 6266-6277 12 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Allogeneic Mesenchymal Precursor Cells Promote Healing in Postero-lateral Annular Lesions and Improve Indices of Lumbar Intervertebral Disc Degeneration in an Ovine Model

Freeman, B. J. C., Kuliwaba, J. S., Jones, C. F., Shu, C. C., Colloca, C. J., Zarrinkalam, M. R., Mulaibrahimovic, A., Gronthos, S., Zannettino, A. C. W. & Howell, S., 1 Sep 2016, In : Spine. 41, 17, p. 1331-1339 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Amino Acid and Peptide Utilization Profiles of the Fluoroacetate-Degrading Bacterium Synergistetes Strain MFA1 Under Varying Conditions

Leong, L. E. X., Denman, S. E., Hugenholtz, P. & McSweeney, C. S., 1 Feb 2016, In : Microbial Ecology. 71, 2, p. 494-504 11 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities

Silva, O. N., De La Fuente-Núñez, C., Haney, E. F., Fensterseifer, I. C. M., Ribeiro, S. M., Porto, W. F., Brown, P., Faria-Junior, C., Rezende, T. M. B., Moreno, S. E., Lu, T. K., Hancock, R. & Franco, O. L., 2 Nov 2016, In : Scientific Reports. 6, 35465.

Research output: Contribution to journalArticle

7 Citations (Scopus)

A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis

Ebert, L. M., Tan, L. Y., Johan, M. Z., Min, K. K. M., Cockshell, M. P., Parham, K. A., Betterman, K. L., Szeto, P., Boyle, S., Silva, L., Peng, A., Zhang, Y. F., Ruszkiewicz, A., Zannettino, A. C. W., Gronthos, S., Koblar, S., Harvey, N. L., Lopez, A. F., Shackleton, M. & Bonder, C. S., 1 Oct 2016, In : Angiogenesis. 19, 4, p. 463-486 24 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

An oncogenic role for sphingosine kinase 2

Neubauer, H. A., Pham, D. H., Zebol, J. R., Moretti, P. A. B., Peterson, A. L., Leclercq, T. M., Chan, H., Powell, J. A., Pitman, M. R., Samuel, M. S., Bonder, C. S., Creek, D. J., Gliddon, B. L. & Pitson, S. M., 1 Jan 2016, In : Oncotarget. 7, 40, p. 64886-64899 14 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response

Armstrong, H. K., Koay, Y. C., Irani, S., Das, R., Nassar, Z. D., Selth, L. A., Centenera, M. M., McAlpine, S. R., Butler, L. M. & The Australian Prostate Cancer BioResource, 1 Dec 2016, In : Prostate. 76, 16, p. 1546-1559 14 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Anticancer efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in osteolytic breast cancer murine models

Liapis, V., Zinonos, I., Labrinidis, A., Hay, S., Ponomarev, V., Panagopoulos, V., Zysk, A., Denichilo, M., Ingman, W., Atkins, G. J., Findlay, D. M., Zannettino, A. C. W. & Evdokiou, A., 1 Mar 2016, In : Cancer Medicine. 5, 3, p. 534-545 12 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

A polyalanine peptide derived from polar fish with anti-infectious activities

Cardoso, M. H., Ribeiro, S. M., Nolasco, D. O., De La Fuente-Núñez, C., Felício, M. R., Gonçalves, S., Matos, C. O., Liao, L. M., Santos, N. C., Hancock, R., Franco, O. L. & Migliolo, L., 26 Feb 2016, In : Scientific Reports. 6, 21385.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Apple intake is inversely associated with all-cause and disease-specific mortality in elderly women

Hodgson, J. M., Prince, R. L., Woodman, R. J., Bondonno, C. P., Ivey, K. L., Bondonno, N., Rimm, E. B., Ward, N. C., Croft, K. D. & Lewis, J. R., 13 Jan 2016, In : British Journal of Nutrition. 115, 5, p. 860-867 8 p.

Research output: Contribution to journalArticle

Assessment of the Influence of Oil Palm and Rubber Plantations in Tropical Peat Swamp Soils Using Microbial Diversity and Activity Analysis

Nurulita, Y., Adetutu, E., Kadali, K. K., Shahsavari, E., Zul, D., Taha, M. & Ball, A. S., May 2016, In : Journal of Agricultural Chemistry and Environment. 5, 2, p. 53-65 13 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Autophagy mediates proteolysis of NPM1 and HEXIM1 and sensitivity to BET inhibition in AML cells

Huang, M., Garcia, J. S., Thomas, D., Zhu, L., Truong Nguyen, L. X., Chan, S. M., Majeti, R., Medeiros, B. C. & Mitchell, B. S., 1 Jan 2016, In : Oncotarget. 7, 46, p. 74917-74930 14 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Bacterial Abscess Formation Is Controlled by the Stringent Stress Response and Can Be Targeted Therapeutically

Mansour, S. C., Pletzer, D., de la Fuente-Núñez, C., Kim, P., Cheung, G. Y. C., Joo, H. S., Otto, M. & Hancock, R., 1 Oct 2016, In : EBioMedicine. 12, p. 219-226 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

BCR-ABL1 expression, RT-qPCR and treatment decisions in chronic myeloid leukaemia

Latham, S., Bartley, P. A., Budgen, B., Ross, D. M., Hughes, E., Branford, S., White, D., Hughes, T. P. & Morley, A. A., 1 Sep 2016, In : Journal of Clinical Pathology. 69, 9, p. 817-821 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Bioinformatics: novel insights from genomic information

Hancock, R., 1 Jan 2016, In : Nestle Nutrition Institute Workshop Series. 84, p. 35-46 12 p.

Research output: Contribution to journalArticle

Botrytis cinerea loss and restoration of virulence during in vitro culture follows flux in global DNA methylation

Breen, J., Mur, L. A. J., Sivakumaran, A., Akinyemi, A., Wilkinson, M. J. & Rodriguez Lopez, C. M., 26 Aug 2016, In : Biorxiv. p. 1-49 49 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Characterization of leukemias with ETV6-ABL1 fusion

Zaliova, M., Moorman, A. V., Cazzaniga, G., Stanulla, M., Harvey, R. C., Roberts, K. G., Heatley, S. L., Loh, M. L., Konopleva, M., Chen, I. M., Zimmermannova, O., Schwab, C., Smith, O., Mozziconacci, M. J., Chabannon, C., Kim, M., Frederik Falkenburg, J. H., Norton, A., Marshall, K., Haas, O. A. & 9 othersStarkova, J., Stuchly, J., Hunger, S. P., White, D., Mullighan, C. G., Willman, C. L., Stary, J., Trka, J. & Zuna, J., 1 Jan 2016, In : Haematologica. 101, 9, p. 1082-1093 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Class I and II histone deacetylase expression in human chronic periodontitis gingival tissue

Cantley, M., Dharmapatni, A. A. S. S. K., Algate, K., Crotti, T. N., Bartold, P. M. & Haynes, D. R., 1 Apr 2016, In : Journal of periodontal research. 51, 2, p. 143-151 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

CNS-specific regulatory elements in brain-derived HIV-1 strains affect responses to latency-reversing agents with implications for cure strategies

Gray, L. R., Cowley, D., Welsh, C., Lu, H. K., Brew, B. J., Lewin, S. R., Wesselingh, S. L., Gorry, P. R. & Churchill, M. J., 1 Apr 2016, In : Molecular Psychiatry. 21, 4, p. 574-584 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia

Lopes, B. A., Meyer, C., Barbosa, T. C., Stadt, U. Z., Horstmann, M., Venn, N. C., Heatley, S., White, D. L., Sutton, R., Pombo-de-Oliveira, M. S., Marschalek, R. & Emerenciano, M., 1 Aug 2016, In : Oncotarget. 7, 33, p. 53064-53073 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Complete genome sequences of the endophytic Streptomyces strains EN16, EN23, and EN27, isolated from wheat plants

Franco, C. M. M., Araujo, R., Adetutu, E., Tobe, S. S., Mallya, S., Paul, B. & Satyamoorthy, K., 1 Nov 2016, In : Genome Announcements. 4, 6, e01342-16.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Compound mutations in BCR-ABL1 are not major drivers of primary or secondary resistance to ponatinib in CP-CML patients

Deininger, M. W., Hodgson, J. G., Shah, N. P., Cortes, J. E., Kim, D. W., Nicolini, F. E., Talpaz, M., Baccarani, M., Müller, M. C., Li, J., Parker, W. T., Lustgarten, S., Clackson, T., Haluska, F. G., Guilhot, F., Kantarjian, H. M., Soverini, S., Hochhaus, A., Hughes, T. P., Rivera, V. M. & 1 othersBranford, S., 11 Feb 2016, In : Blood. 127, 6, p. 703-712 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling

Broughton, S. E., Hercus, T. R., Nero, T. L., Dottore, M., McClure, B. J., Dhagat, U., Taing, H., Gorman, M. A., King-Scott, J., Lopez, A. F. & Parker, M. W., 2 Aug 2016, In : Structure. 24, 8, p. 1271-1281 11 p.

Research output: Contribution to journalArticle

Contextual Hub Analysis Tool (CHAT): A Cytoscape app for identifying contextually relevant hubs in biological networks [version 2; referees: 2 approved]

Muetze, T., Goenawan, I. H., Wiencko, H. L., Bernal-Llinares, M., Bryan, K. & Lynn, D., 1 Jan 2016, In : F1000Research. 5, 1745.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Contextual Hub Analysis Tool (CHAT): A Cytoscape app for identifying contextually relevant hubs in biological networks [version 1; referees: 1 approved]

Muetze, T., Goenawan, I. H., Wiencko, H. L., Bernal-Llinares, M., Bryan, K. & Lynn, D., 1 Jan 2016, In : F1000Research. 5, 1745.

Research output: Contribution to journalArticle