Research Output

2018

Large deletions induced by Cas9 cleavage

Adikusuma, F., Piltz, S., Corbett, M. A., Turvey, M., McColl, S. R., Helbig, K. J., Beard, M. R., Hughes, J., Pomerantz, R. T. & Thomas, P., 9 Aug 2018, In : Nature. 560, 7717, p. E8-E9

Research output: Contribution to journalArticle

33 Citations (Scopus)

Leukemia in gastrointestinal organs as cause of treatment failure: 378 cases analyzed

Cunningham, I. & Worthley, D., 1 Nov 2018, In : American Journal of Hematology. 93, 11, p. 1327-1336 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Long-term colonisation with donor bacteriophages following successful faecal microbial transplantation

Draper, L. A., Ryan, F., Smith, M. K., Jalanka, J., Mattila, E., Arkkila, P. A., Ross, R. P., Satokari, R. & Hill, C., 10 Dec 2018, In : Microbiome. 6, 1, 220.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Long-term treatment-free remission of chronic myeloid leukemia with falling levels of residual leukemic cells

on behalf of the Australasian Leukaemia and Lymphoma Group (ALLG), 1 Dec 2018, In : Leukemia. 32, 12, p. 2572-2579 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Management of pregnancy in women with chronic myeloid leukemia

Ross, D. M., Burbury, K. L., Grigg, A. P., Hughes, T. & Seymour, J. F., 1 Sep 2018, In : Journal of Clinical Oncology. 36, 25, p. 2657-2658 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Measuring research impact: A large cancer research funding programme in Australia

Bowden, J., Sargent, N., Wesselingh, S., Size, L., Donovan, C. & Miller, C., 9 May 2018, In : Health Research Policy and Systems. 16, 1, 39.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Mesenchymal progenitor cells primed with pentosan polysulfate promote lumbar intervertebral disc regeneration in an ovine model of microdiscectomy

Daly, C. D., Ghosh, P., Zannettino, A., Badal, T., Shimmon, R., Jenkin, G., Oehme, D., Jain, K., Sher, I., Vais, A., Cohen, C., Chandra, R. V. & Goldschlager, T., 1 Mar 2018, In : Spine Journal. 18, 3, p. 491-506 16 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

MetaBridge: Enabling network-based integrative analysis via direct protein interactors of metabolites

Hinshaw, S. J., Lee, A. H. Y., Gill, E. E. & Hancock, R., 1 Jan 2018, In : Bioinformatics. 34, 18, p. 3225-3227 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Metatranscriptome of human faecal microbial communities in a cohort of adult men

Abu-Ali, G. S., Mehta, R. S., Lloyd-Price, J., Mallick, H., Branck, T., Ivey, K., Drew, D. A., Dulong, C., Rimm, E., Izard, J., Chan, A. T. & Huttenhower, C., 1 Mar 2018, In : Nature Microbiology. 3, 3, p. 356-366 11 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Microbial Degradation of Phenanthrene in Pristine and Contaminated Sandy Soils

Schwarz, A., Adetutu, E. M., Juhasz, A. L., Aburto-Medina, A., Ball, A. S. & Shahsavari, E., 1 May 2018, In : Microbial Ecology. 75, 4, p. 888-902 15 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Modelling ponatinib resistance in tyrosine kinase inhibitor-naïve and dasatinib resistant BCR-ABL1+ cell lines

Lu, L., Kok, C. H., Saunders, V. A., Wang, J., McLean, J. A., Hughes, T. & White, D. L., 1 Oct 2018, In : Oncotarget. 9, 78, p. 34735-34747 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Molecular monitoring in CML: How deep? How often? How should it influence therapy?

Shanmuganathan, N. & Hughes, T., 15 Nov 2018, In : Blood. 132, 20, p. 2125-2133 9 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Molecular monitoring in CML: How deep? How often? How should it influence therapy?

Shanmuganathan, N. & Hughes, T., 30 Nov 2018, In : Hematology. 2018, 1, p. 168-176 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

MsgbsR: An R package for analysing methylation-sensitive restriction enzyme sequencing data

Mayne, B. T., Leemaqz, S. Y., Buckberry, S., Rodriguez Lopez, C. M., Roberts, C. T., Bianco-Miotto, T. & Breen, J., 1 Dec 2018, In : Scientific Reports. 8, 1, 2190.

Research output: Contribution to journalArticle

1 Citation (Scopus)

mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis

Martin, S. K., Fitter, S., El Khawanky, N., Grose, R., Walkley, C. R., Purton, L. E., Ruegg, M. A., Hall, M. N., Gronthos, S. & Zannettino, A., 1 Dec 2018, In : Scientific Reports. 8, 1, 14501.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Multi-Centre Ethics and Research Governance Review Can Impede Non-Interventional Clinical Research

Duplancic, C., Crough, T., Bell, S. C. & Rogers, G., 12 Nov 2018, In : Internal Medicine Journal.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Network Visualization and Analysis of Spatially Aware Gene Expression Data with InsituNet

Salamon, J., Qian, X., Nilsson, M. & Lynn, D. J., 23 May 2018, In : Cell Systems. 6, 5, p. 626-630.e3

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)

New Opportunities for Targeting the Androgen Receptor in Prostate Cancer

Centenera, M. M., Selth, L. A., Ebrahimie, E., Butler, L. & Tilley, W. D., 3 Dec 2018, In : Cold Spring Harbor Perspectives in Medicine. 8, 12

Research output: Contribution to journalReview article

8 Citations (Scopus)

New Opportunities for Targeting the Androgen Receptor in Prostate Cancer

Centenera, M. M., Selth, L. A., Ebrahimie, E., Butler, L. & Tilley, W. D., 3 Dec 2018, In : Cold Spring Harbor perspectives in medicine. 8, 12

Research output: Contribution to journalReview article

Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia

Bond, C. E., Liu, C., Kawamata, F., McKeone, D. M., Fernando, W., Jamieson, S., Pearson, S. A., Kane, A., Woods, S. L., Lannagan, T. R. M., Somashekar, R., Lee, Y., Dumenil, T., Hartel, G., Spring, K. J., Borowsky, J., Fennell, L., Bettington, M., Lee, J., Worthley, D. L. & 2 othersLeggett, B. A. & Whitehall, V. L. J., 2 Jan 2018, In : Epigenetics. 13, 1, p. 40-48 9 p.

Research output: Contribution to journalArticle

Open Access
21 Citations (Scopus)

Optimisation of a propidium monoazide based method to determine the viability of microbes in faecal slurries for transplantation

Papanicolas, L. E., Wang, Y., Choo, J. M., Gordon, D. L., Wesselingh, S. L. & Rogers, G. B., 4 Dec 2018, In : Journal of microbiological methods. 156, p. 40-45 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats

Su, Y. W., Chim, S. M., Zhou, L., Hassanshahi, M., Chung, R., Fan, C., Song, Y., Foster, B. K., Prestidge, C. A., Peymanfar, Y., Tang, Q., Butler, L., Gronthos, S., Chen, D., Xie, Y., Chen, L., Zhou, X. F., Xu, J. & Xian, C. J., 1 Nov 2018, In : Bone. 116, p. 232-247 16 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Osteocalcin-dependent regulation of glucose metabolism and fertility: Skeletal implications for the development of insulin resistance

Tangseefa, P., Martin, S. K., Fitter, S., Baldock, P. A., Proud, C. G. & Zannettino, A. C. W., 1 May 2018, In : Journal of Cellular Physiology. 233, 5, p. 3769-3783 15 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Osteopontin in the pathophysiology of obesity: Is Opn a fat cell foe?

Fitter, S. & Zannettino, A., 1 May 2018, In : Obesity Research and Clinical Practice. 12, 3, p. 249-250 2 p.

Research output: Contribution to journalEditorial

Overexpression of HER2 in the pancreas promotes development of intraductal papillary mucinous neoplasms in mice

Shibata, W., Kinoshita, H., Hikiba, Y., Sato, T., Ishii, Y., Sue, S., Sugimori, M., Suzuki, N., Sakitani, K., Ijichi, H., Mori, R., Endo, I. & Maeda, S., 1 Dec 2018, In : Scientific Reports. 8, 1, 6150.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Parallel assembly of actin and tropomyosin, but not myosin II, during de novo actin filament formation in live mice

Masedunskas, A., Appaduray, M. A., Lucas, C. A., Cagigas, M. L., Heydecker, M., Holliday, M., Meiring, J. C. M., Hook, J., Kee, A., White, M., Thomas, P., Zhang, Y., Adelstein, R. S., Meckel, T., Böcking, T., Weigert, R., Bryce, N. S., Gunning, P. W. & Hardeman, E. C., 1 Mar 2018, In : Journal of Cell Science. 131, 6, jcs212654.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Patient-derived Models Reveal Impact of the Tumor Microenvironment on Therapeutic Response

Shafi, A. A., Schiewer, M. J., de Leeuw, R., Dylgjeri, E., McCue, P. A., Shah, N., Gomella, L. G., Lallas, C. D., Trabulsi, E. J., Centenera, M. M., Hickey, T. E., Butler, L., Raj, G. V., Tilley, W. D., Cukierman, E. & Knudsen, K. E., 1 Sep 2018, In : European Urology Oncology. 1, 4, p. 325-337 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Patient perceptions of treatment-free remission in chronic myeloid leukemia

Villemagne Sanchez, L. A., O’Callaghan, C., Gough, K., Hall, K., Kashima, Y., Seymour, J. F., Schofield, P. & Ross, D., 1 Feb 2018, In : Leukemia and Lymphoma. 59, 2, p. 406-415 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
4 Citations (Scopus)

PCDH19 regulation of neural progenitor cell differentiation suggests asynchrony of neurogenesis as a mechanism contributing to PCDH19 Girls Clustering Epilepsy

Homan, C. C., Pederson, S., To, T. H., Tan, C., Piltz, S., Corbett, M. A., Wolvetang, E., Thomas, P. Q., Jolly, L. A. & Gecz, J., 1 Aug 2018, In : Neurobiology of Disease. 116, p. 106-119 14 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Peri-prostatic adipose tissue: the metabolic microenvironment of prostate cancer

Nassar, Z. D., Aref, A. T., Miladinovic, D., Mah, C. Y., Raj, G. V., Hoy, A. J. & Butler, L., 1 May 2018, In : BJU International. 121, p. 9-21 13 p.

Research output: Contribution to journalReview article

12 Citations (Scopus)

Pest demography critically determines the viability of synthetic gene drives for population control

Wilkins, K. E., Prowse, T. A. A., Cassey, P., Thomas, P. & Ross, J. V., 1 Nov 2018, In : Mathematical Biosciences. 305, p. 160-169 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Ponatinib efficacy and safety in Philadelphia chromosome–positive leukemia: final 5-year results of the phase 2 PACE trial

Cortes, J. E., Kim, D. W., Pinilla-Ibarz, J., le Coutre, P. D., Paquette, R., Chuah, C., Nicolini, F. E., Apperley, J. F., Khoury, H. J., Talpaz, M., DeAngelo, D. J., Abruzzese, E., Rea, D., Baccarani, M., Müller, M. C., Gambacorti-Passerini, C., Lustgarten, S., Rivera, V. M., Haluska, F. G., Guilhot, F. & 5 othersDeininger, M. W., Hochhaus, A., Hughes, T., Shah, N. P. & Kantarjian, H. M., 26 Jul 2018, In : Blood. 132, 4, p. 393-404 12 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Potential of iPSC-derived mesenchymal stromal cells for treating periodontal disease

Hynes, K., Bright, R., Marino, V., Ng, J., Verma, P. J., Gronthos, S. & Bartold, P. M., 1 Jan 2018, In : Stem Cells International. 2018, 2601945.

Research output: Contribution to journalArticle

7 Citations (Scopus)

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa

Burr, L. D., Rogers, G., Chen, A. C. H., Taylor, S., Bowler, S. D., Keating, R. L., Martin, M. L., Hasnain, S. Z. & McGuckin, M. A., 1 Aug 2018, In : PloS one. 13, 8, e0202296.

Research output: Contribution to journalArticle

Pre-B acute lymphoblastic leukaemia recurrent fusion, EP300-ZNF384, is associated with a distinct gene expression

McClure, B., Heatley, S., Kok, C., Sadras, T., An, J., Hughes, T., Lock, R. B., Yeung, D., Sutton, R. & White, D., 1 Apr 2018, In : British Journal of Cancer. 118, 7, p. 1000-1004 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Precision nanomedicines for prostate cancer

Cifuentes-Rius, A., Butler, L. & Voelcker, N. H., 1 Apr 2018, In : Nanomedicine. 13, 8, p. 803-807 5 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Prospective study of flavonoid intake and risk of primary open-angle glaucoma

Kang, J. H., Ivey, K., Boumenna, T., Rosner, B., Wiggs, J. L. & Pasquale, L. R., 1 Sep 2018, In : Acta Ophthalmologica. 96, 6, p. e692-e700

Research output: Contribution to journalArticle

7 Citations (Scopus)

Retinoic acid elicits a coordinated expression of gut homing markers on T lymphocytes of Zambian men receiving oral Vivotif, but not Rotarix, Dukoral or OPVERO vaccines

Mwanza-Lisulo, M., Chomba, M. S., Chama, M., Besa, E. C., Funjika, E., Zyambo, K., Banda, R., Imikendu, M., Sianongo, S., Hancock, R., Lee, A., Chilengi, R., Stagg, A. J., Namangala, B. & Kelly, P. M., 27 Jun 2018, In : Vaccine. 36, 28, p. 4134-4141 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Role of the β common (βc) family of cytokines in health and disease

Hercus, T. R., Kan, W. L. T., Broughton, S. E., Tvorogov, D., Ramshaw, H. S., Sandow, J. J., Nero, T. L., Dhagat, U., Thompson, E. J., Tung Shing, K. S. C., McKenzie, D. R., Wilson, N. J., Owczarek, C. M., Vairo, G., Nash, A. D., Tergaonkar, V., Hughes, T., Ekert, P. G., Samuel, M. S., Bonder, C. S. & 3 othersGrimbaldeston, M. A., Parker, M. W. & Lopez, A. F., 1 Jun 2018, In : Cold Spring Harbor perspectives in biology. 10, 6, a028514.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Stability of the human faecal microbiome in a cohort of adult men

Mehta, R. S., Abu-Ali, G. S., Drew, D. A., Lloyd-Price, J., Subramanian, A., Lochhead, P., Joshi, A. D., Ivey, K., Khalili, H., Brown, G. T., Dulong, C., Song, M., Nguyen, L. H., Mallick, H., Rimm, E. B., Izard, J., Huttenhower, C. & Chan, A. T., 1 Mar 2018, In : Nature Microbiology. 3, 3, p. 347-355 9 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Success is built on failures: tackling the challenge of ponatinib failure

Hiwase, D. & Ross, D., 3 Jun 2018, In : Leukemia and Lymphoma. 59, 6, p. 1279-1281 3 p.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

Surfing motility: A conserved yet diverse adaptation among motile bacteria

Sun, E., Liu, S. & Hancock, R., 1 Dec 2018, In : Journal of bacteriology. 200, 23, e00394.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Synergy between conventional antibiotics and anti-biofilm peptides in a murine, sub-cutaneous abscess model caused by recalcitrant ESKAPE pathogens

Pletzer, D., Mansour, S. C. & Hancock, R., 1 Jun 2018, In : PLoS Pathogens. 14, 6, e1007084.

Research output: Contribution to journalArticle

29 Citations (Scopus)

The inverse relationship between prostate specific antigen (PSA) and obesity

Aref, A. T., Vincent, A. D., O'Callaghan, M. E., Martin, S. A., Sutherland, P. D., Hoy, A. J., Butler, L. & Wittert, G., 1 Nov 2018, In : Endocrine-Related Cancer. 25, 11, p. 933-941 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities

Dhagat, U., Hercus, T. R., Broughton, S. E., Nero, T. L., Cheung Tung Shing, K. S., Barry, E. F., Thomson, C. A., Bryson, S., Pai, E. F., McClure, B., Schrader, J. W., Lopez, A. F. & Parker, M. W., 3 Oct 2018, In : mAbs. 10, 7, p. 1018-1029 12 p.

Research output: Contribution to journalArticle

The Microbiota-Inflammasome Hypothesis of Major Depression

Inserra, A., Rogers, G. B., Licinio, J. & Wong, M. L., 1 Sep 2018, In : BioEssays. 40, 9, 1800027.

Research output: Contribution to journalReview article

19 Citations (Scopus)