Research Output 1987 2019

2017
5 Citations (Scopus)

Peroxidase enzymes inhibit osteoclast differentiation and bone resorption

Panagopoulos, V., Liapis, V., Zinonos, I., Hay, S., Leach, D. A., Ingman, W., DeNichilo, M. O., Atkins, G. J., Findlay, D. M., Zannettino, A. C. W. & Evdokiou, A., 15 Jan 2017, In : Molecular and Cellular Endocrinology. 440, p. 8-15 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Phage-derived protein induces increased platelet activation and is associated with mortality in patients with invasive pneumococcal disease

Tunjungputri, R. N., Mobegi, F., Cremers, A. J., van der Gaast-de Jongh, C. E., Ferwerda, G., Meis, J. F., Roeleveld, N., Bentley, S. D., Pastura, A. S., van Hijum, S. A. F. T., van der Ven, A. J., de Mast, Q., Zomer, A. & de Jonge, M. I., 1 Jan 2017, In : mBio. 8, 1, e01984-16.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Protocadherin 19 (PCDH19) interacts with paraspeckle protein NONO to co-regulate gene expression with estrogen receptor alpha (ERα)

Pham, D. H., Tan, C. C., Homan, C. C., Kolc, K. L., Corbett, M. A., McAninch, D., Fox, A. H., Thomas, P. Q., Kumar, R. & Gecz, J., 1 Jan 2017, In : Human Molecular Genetics. 26, 11, p. 2042-2052 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Red cell alloimmunization is associated with development of autoantibodies and increased red cell transfusion requirements in myelodysplastic syndrome

Singhal, D., Kutyna, M. M., Chhetri, R., Wee, L. Y. A., Hague, S., Nath, L., Nath, S. V., Sinha, R., Wickham, N., Lewis, I. D., Ross, D. M., Bardy, P. G., To, L. B., Reynolds, J., Wood, E. M., Roxby, D. J. & Hiwase, D., 30 Nov 2017, In : Haematologica. 102, 12, p. 2021-2029 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Reduced CD62L expression on T cells and increased soluble CD62L levels predict molecular response to tyrosine kinase inhibitor therapy in early chronic-phase chronic myelogenous leukemia

Sopper, S., Mustjoki, S., White, D., Hughes, T., Valent, P., Burchert, A., Gjertsen, B. T., Gastl, G., Baldauf, M., Trajanoski, Z., Giles, F., Hochhaus, A., Ernst, T., Schenk, T., Janssen, J. J. W. M., Ossenkoppele, G. J., Porkka, K. & Wolf, D., 10 Jan 2017, In : Journal of Clinical Oncology. 35, 2, p. 175-184 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Retinal pigment epithelial cells are a potential reservoir for ebola virus in the Human Eye

Smith, J. R., Todd, S., Ashander, L. M., Charitou, T., Ma, Y., Yeh, S., Crozier, I., Michael, M. Z., Appukuttan, B., Williams, K. A., Lynn, D. & Marsh, G. A., 1 Jul 2017, In : Translational Vision Science and Technology. 6, 4, 12.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress

Wallington-Beddoe, C. T., Bennett, M. K., Vandyke, K., Davies, L., Zebol, J. R., Moretti, P. A. B., Pitman, M. R., Hewett, D. R., Zannettino, A. C. W. & Pitson, S. M., 1 Jan 2017, In : Oncotarget. 8, 27, p. 43602-43616 15 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Standardization of Criteria Defining Periodontal Ligament Stem Cells

Bartold, P. M. & Gronthos, S., 1 May 2017, In : Journal of Dental Research. 96, 5, p. 487-490 4 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo

Murray, J., Valli, E., Yu, D. M. T., Truong, A. M., Gifford, A. J., Eden, G., Gamble, L. D., Hanssen, K. M., Flemming, C. L., Tan, A., Tivnan, A., Allan, S., Saletta, F., Cheung, L., Ruhle, M., Schuetz, J. D., Henderson, M. J., Byrne, J. A., Norris, M. D., Haber, M. & 1 othersFletcher, J. I., 1 Sep 2017, In : European Journal of Cancer. 83, p. 132-141 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Sustained deep molecular responses in patients switched to nilotinib due to persistent BCR-ABL1 on imatinib: final ENESTcmr randomized trial results

Hughes, T. P., Leber, B., Cervantes, F., Spector, N., Pasquini, R., Clementino, N. C. D., Schwarer, A. P., Dorlhiac-Llacer, P. E., Mahon, F-X., Rea, D., Guerci-Bresler, A., Kamel-Reid, S., Bendit, I., Acharya, S., Glynos, T., Dalal, D., Branford, S. & Lipton, J. H., 3 Aug 2017, In : Leukemia.

Research output: Contribution to journalArticle

Systems approaches for identifying disease genes and drug targets

Srihari, S., 1 Dec 2017, In : Methods. 131, p. 1-3 3 p.

Research output: Contribution to journalEditorial

12 Citations (Scopus)

Targeted Deletion of an Entire Chromosome Using CRISPR/Cas9

Adikusuma, F., Williams, N., Grutzner, F., Hughes, J. & Thomas, P., 2 Aug 2017, In : Molecular Therapy. 25, 8, p. 1736-1738 3 p.

Research output: Contribution to journalLetter

3 Citations (Scopus)

Targeted therapies: Remembrance of things past - Discontinuation of second-generation TKI therapy for CML

Hughes, T. & Ross, D. M., 1 Apr 2017, In : Nature Reviews Clinical Oncology. 14, 4, p. 201-202 2 p.

Research output: Contribution to journalShort survey

55 Citations (Scopus)

Th2 cells in health and disease

Nakayama, T., Hirahara, K., Onodera, A., Endo, Y., Hosokawa, H., Shinoda, K., Tumes, D. J. & Okamoto, Y., 26 Apr 2017, In : Annual Review of Immunology. 35, p. 53-84 32 p.

Research output: Contribution to journalReview article

84 Citations (Scopus)

The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1

Wylie, A. A., Schoepfer, J., Jahnke, W., Cowan-Jacob, S. W., Loo, A., Furet, P., Marzinzik, A. L., Pelle, X., Donovan, J., Zhu, W., Buonamici, S., Hassan, A. Q., Lombardo, F., Iyer, V., Palmer, M., Berellini, G., Dodd, S., Thohan, S., Bitter, H., Branford, S. & 8 othersRoss, D. M., Hughes, T. P., Petruzzelli, L., Vanasse, K. G., Warmuth, M., Hofmann, F., Keen, N. J. & Sellers, W. R., 30 Mar 2017, In : Nature. 543, 7647, p. 733-737 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells

Vuckovic, S., Vandyke, K., Rickards, D. A., Mccauley Winter, P., Brown, S. H. J., Mitchell, T. W., Liu, J., Lu, J., Askenase, P. W., Yuriev, E., Capuano, B., Ramsland, P. A., Hill, G. R., Zannettino, A. C. W. & Hutchinson, A. T., 1 May 2017, In : British Journal of Haematology. 177, 3, p. 423-440 18 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
11 Citations (Scopus)

The combination of metformin and valproic acid induces synergistic apoptosis in the presence of p53 and androgen signaling in prostate cancer

Tran, L. N. K., Kichenadasse, G., Butler, L. M., Centenera, M. M., Morel, K. L., Ormsby, R. J., Michael, M. Z., Lower, K. M. & Sykes, P. J., 1 Dec 2017, In : Molecular Cancer Therapeutics. 16, 12, p. 2689-2700 12 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

The diverse metabolic roles of peripheral serotonin

Martin, A. M., Young, R. L., Leong, L., Rogers, G. B., Spencer, N. J., Jessup, C. F. & Keating, D. J., 1 Mar 2017, In : Endocrinology.

Research output: Contribution to journalArticle

5 Citations (Scopus)

The G-protein coupled receptor 56, expressed in colonic stem and cancer cells, binds progastrin to promote proliferation and carcinogenesis

Jin, G., Sakitani, K., Wang, H., Jin, Y., Dubeykovskiy, A., Worthley, D. L., Tailor, Y. & Wang, T. C., 1 Jan 2017, In : Oncotarget. 8, 25, p. 40606-40619 14 p.

Research output: Contribution to journalArticle

The incidence and natural history of dasatinib complications in the treatment of chronic myeloid leukemia

Fox, L. C., Cummins, K. D., Costello, B., Yeung, D., Cleary, R., Forsyth, C. J., Tatarczuch, M., Burbury, K., Motorna, O., Shortt, J., Fleming, S., McQuillan, A., Schwarer, A. P., Harrup, R., Holmes, A., Ratnasingam, S., Chan, K., Hsu, W., Ashraf, A., Putt, F. & 1 othersGrigg, A., 2017, In : Blood Advances. 1, 13, p. 802-811 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

The Mesenchymal Precursor Cell Marker Antibody STRO-1 Binds to Cell Surface Heat Shock Cognate 70

Fitter, S., Gronthos, S., Ooi, S. S. & Zannettino, A. C. W., 1 Apr 2017, In : Stem Cells. 35, 4, p. 940-951 12 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

The potential of the microbiota to influence vaccine responses

Lynn, D. J. & Pulendran, B., 1 Sep 2017, In : Journal of Leukocyte Biology. 103, 2, p. 225-231 7 p., 28864446 .

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)

Transcriptome profiling of IL-17A preactivated mesenchymal stem cells: A comparative study to unmodified and IFN- γ modified mesenchymal stem cells

Sivanathan, K. N., Rojas-Canales, D., Grey, S. T., Gronthos, S. & Coates, P. T., 2017, In : Stem Cells International. 2017, 1025820.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Treatment of chronic myeloid leukemia: assessing risk, monitoring response, and optimizing outcome

Shanmuganathan, N., Hiwase, D. K. & Ross, D. M., 2 Dec 2017, In : Leukemia and Lymphoma. 58, 12, p. 2799-2810 12 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Treatment of patients with Waldenström macroglobulinaemia: clinical practice guidelines from the Myeloma Foundation of Australia Medical and Scientific Advisory Group

Talaulikar, D., Tam, C. S., Joshua, D., Ho, J. P., Szer, J., Quach, H., Spencer, A., Harrison, S., Mollee, P., Roberts, A. W., Horvath, N., Lee, C., Zannettino, A., Brown, R., Augustson, B., Jaksic, W., Gibson, J., Kalff, A., Johnston, A., Trotman, J. & 4 othersKalro, A., Grigoriadis, G., Ward, C. & Prince, H. M., 1 Jan 2017, In : Internal Medicine Journal. 47, 1, p. 35-49 15 p.

Research output: Contribution to journalArticle

126 Citations (Scopus)

Tumour-associated and non-tumour-associated microbiota in colorectal cancer

Flemer, B., Lynch, D. B., Brown, J. M. R., Jeffery, I. B., Ryan, F., Claesson, M. J., O'Riordain, M., Shanahan, F. & O'Toole, P. W., 1 Apr 2017, In : Gut. 66, 4, p. 633-643 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Tyrosine kinase receptor c-ros-oncogene 1 mediates TWIST-1 regulation of human mesenchymal stem cell lineage commitment

Camp, E., Anderson, P. J., Zannettino, A. C. W. & Gronthos, S., 1 Jan 2017, In : Bone. 94, p. 98-107 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Using the contextual hub analysis tool (CHAT) in cytoscape to identify contextually relevant network hubs

Muetze, T. & Lynn, D. J., 2017, In : Current Protocols in Bioinformatics. 2017, p. 8.24.1-8.24.13 8 p., 10.1002/cpbi.35.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)

Versatile single-step-assembly CRISPR/Cas9 vectors for dual gRNA expression

Adikusuma, F., Pfitzner, C. & Thomas, P., 1 Dec 2017, In : PLoS ONE. 12, 12, e0187236.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Viperin is an important host restriction factor in control of Zika virus infection

Van Der Hoek, K. H., Eyre, N. S., Shue, B., Khantisitthiporn, O., Glab-Ampi, K., Carr, J. M., Gartner, M. J., Jolly, L. A., Thomas, P., Adikusuma, F., Jankovic-Karasoulos, T., Roberts, C. T., Helbig, K. J. & Beard, M. R., 1 Dec 2017, In : Scientific Reports. 7, 1, 4138.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Whole exome sequencing implicates eye development, the unfolded protein response and plasma membrane homeostasis in primary open-angle glaucoma

Zhou, T., Souzeau, E., Sharma, S., Landers, J., Mills, R., Goldberg, I., Healey, P. R., Graham, S., Hewitt, A. W., Mackey, D. A., Galanopoulos, A., Casson, R. J., Ruddle, J. B., Ellis, J., Leo, P., Brown, M. A., MacGregor, S., Lynn, D. J., Burdon, K. P. & Craig, J. E., 1 Mar 2017, In : PLoS ONE. 12, 3, e0172427.

Research output: Contribution to journalArticle

2016
13 Citations (Scopus)
15 Citations (Scopus)

Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance

Walia, M. K., Ho, P. M. W., Taylor, S., Ng, A. J. M., Gupte, A., Chalk, A. M., Zannettino, A. C. W., Martin, T. J. & Walkley, C. R., 12 Apr 2016, In : eLife. 5, April 2016, e13446.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Acute sensitivity of Ph-like acute lymphoblastic leukemia to the SMAC-mimetic birinapant

Richmond, J., Robbins, A., Evans, K., Beck, D., Kurmasheva, R. T., Billups, C. A., Carol, H., Heatley, S., Sutton, R., Marshall, G. M., White, D., Pimanda, J., Houghton, P. J., Smith, M. A. & Lock, R. B., 1 Aug 2016, In : Cancer Research. 76, 15, p. 4579-4591 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

A genome-wide association study for genetic susceptibility to Mycobacterium bovis infection in dairy cattle identifies a susceptibility QTL on chromosome 23

Richardson, I. W., Berry, D. P., Wiencko, H. L., Higgins, I. M., More, S. J., McClure, J., Lynn, D. & Bradley, D. G., 9 Mar 2016, In : Genetics Selection Evolution. 48, 1, 197.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Agonistic CD40 mAb-driven IL12 reverses resistance to anti-PD1 in a T-cell-rich tumor

Ngiow, S. F., Young, A., Blake, S. J., Hill, G. R., Yagita, H., Teng, M. W. L., Korman, A. J. & Smyth, M. J., 1 Nov 2016, In : Cancer Research. 76, 21, p. 6266-6277 12 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Allogeneic Mesenchymal Precursor Cells Promote Healing in Postero-lateral Annular Lesions and Improve Indices of Lumbar Intervertebral Disc Degeneration in an Ovine Model

Freeman, B. J. C., Kuliwaba, J. S., Jones, C. F., Shu, C. C., Colloca, C. J., Zarrinkalam, M. R., Mulaibrahimovic, A., Gronthos, S., Zannettino, A. C. W. & Howell, S., 1 Sep 2016, In : Spine. 41, 17, p. 1331-1339 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Amino Acid and Peptide Utilization Profiles of the Fluoroacetate-Degrading Bacterium Synergistetes Strain MFA1 Under Varying Conditions

Leong, L. E. X., Denman, S. E., Hugenholtz, P. & McSweeney, C. S., 1 Feb 2016, In : Microbial Ecology. 71, 2, p. 494-504 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Androgen control of lipid metabolism in prostate cancer: Novel insights and future applications

Butler, L. M., Centenera, M. M. & Swinnen, J. V., 1 May 2016, In : Endocrine-Related Cancer. 23, 5, p. R219-R227

Research output: Contribution to journalReview article

7 Citations (Scopus)

A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis

Ebert, L. M., Tan, L. Y., Johan, M. Z., Min, K. K. M., Cockshell, M. P., Parham, K. A., Betterman, K. L., Szeto, P., Boyle, S., Silva, L., Peng, A., Zhang, Y. F., Ruszkiewicz, A., Zannettino, A. C. W., Gronthos, S., Koblar, S., Harvey, N. L., Lopez, A. F., Shackleton, M. & Bonder, C. S., 1 Oct 2016, In : Angiogenesis. 19, 4, p. 463-486 24 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

An oncogenic role for sphingosine kinase 2

Neubauer, H. A., Pham, D. H., Zebol, J. R., Moretti, P. A. B., Peterson, A. L., Leclercq, T. M., Chan, H., Powell, J. A., Pitman, M. R., Samuel, M. S., Bonder, C. S., Creek, D. J., Gliddon, B. L. & Pitson, S. M., 2016, In : Oncotarget. 7, 40, p. 64886-64899 14 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response

Armstrong, H. K., Koay, Y. C., Irani, S., Das, R., Nassar, Z. D., Selth, L. A., Centenera, M. M., McAlpine, S. R., Butler, L. M. & The Australian Prostate Cancer BioResource, 1 Dec 2016, In : Prostate. 76, 16, p. 1546-1559 14 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Anticancer efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in osteolytic breast cancer murine models

Liapis, V., Zinonos, I., Labrinidis, A., Hay, S., Ponomarev, V., Panagopoulos, V., Zysk, A., Denichilo, M., Ingman, W., Atkins, G. J., Findlay, D. M., Zannettino, A. C. W. & Evdokiou, A., 1 Mar 2016, In : Cancer Medicine. 5, 3, p. 534-545 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Anti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity

Souza-Fonseca-Guimaraes, F., Blake, S., Makkouk, A., Chester, C., Kohrt, H. E. & Smyth, M. J., 2 Jul 2016, In : OncoImmunology. 5, 7, e1192740.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Apple intake is inversely associated with all-cause and disease-specific mortality in elderly women

Hodgson, J. M., Prince, R. L., Woodman, R. J., Bondonno, C. P., Ivey, K. L., Bondonno, N., Rimm, E. B., Ward, N. C., Croft, K. D. & Lewis, J. R., 13 Jan 2016, In : British Journal of Nutrition. 115, 5, p. 860-867 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Assessing immune-related adverse events of efficacious combination immunotherapies in preclinical models of cancer

Liu, J., Blake, S., Harjunpää, H., Fairfax, K. A., Yong, M. C. R., Allen, S., Kohrt, H. E., Takeda, K., Smyth, M. J. & Teng, M. W. L., 15 Sep 2016, In : Cancer Research. 76, 18, p. 5288-5301 14 p.

Research output: Contribution to journalArticle

Assessment of the Influence of Oil Palm and Rubber Plantations in Tropical Peat Swamp Soils Using Microbial Diversity and Activity Analysis

Nurulita, Y., Adetutu, E., Kadali, K. K., Shahsavari, E., Zul, D., Taha, M. & Ball, A. S., May 2016, In : Journal of Agricultural Chemistry and Environment. 5, 2, p. 53-65 13 p.

Research output: Contribution to journalArticle

Open Access