Research Output

2020

Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy

Kamili, A., Gifford, A. J., Li, N., Mayoh, C., Chow, S. O., Failes, T. W., Eden, G., Cadiz, R., Xie, J., Lukeis, R. E., Norris, M. D., Haber, M., McCowage, G. B., Arndt, G. M., Trahair, T. N. & Fletcher, J. I., 3 Mar 2020, In : British Journal of Cancer. 122, 5, p. 680-691 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Allogeneic primary mesenchymal stem/stromal cell aggregates within poly(N-isopropylacrylamide-co-acrylic acid) hydrogel for osteochondral regeneration

Zhang, J., Zhang, M., Lin, R., Yun, S., Du, Y., Wang, L., Yao, Q., Zannettino, A. & Zhang, H., 1 Mar 2020, In : Applied Materials Today. 18, 100487.

Research output: Contribution to journalArticle

Association Between Sulfur-Metabolizing Bacterial Communities in Stool and Risk of Distal Colorectal Cancer in Men

Nguyen, L. H., Ma, W., Wang, D. D., Cao, Y., Mallick, H., Gerbaba, T. K., Lloyd-Price, J., Abu-Ali, G., Hall, A. B., Sikavi, D., Drew, D. A., Mehta, R. S., Arze, C., Joshi, A. D., Yan, Y., Branck, T., DuLong, C., Ivey, K. L., Ogino, S., Rimm, E. B. & 5 othersSong, M., Garrett, W. S., Izard, J., Huttenhower, C. & Chan, A. T., 20 Jan 2020, In : Gastroenterology.

Research output: Contribution to journalArticle

Comprehensive geriatric assessment predicts azacitidine treatment duration and survival in older patients with myelodysplastic syndromes

Molga, A., Wall, M., Chhetri, R., Wee, L. Y., Singhal, D., Edwards, S., Singhal, N., Ross, D., To, L. B., Caughey, G., Shakib, S., Germing, U., To, T. & Hiwase, D., 1 Jan 2020, In : Journal of Geriatric Oncology. 11, 1, p. 114-120 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Data-driven multivariate population subgrouping via lipoprotein phenotypes versus apolipoprotein B in the risk assessment of coronary heart disease

Ohukainen, P., Kuusisto, S., Kettunen, J., Perola, M., Järvelin, M. R., Makinen, V-P. & Ala-Korpela, M., 1 Feb 2020, In : Atherosclerosis. 294, p. 10-15 6 p.

Research output: Contribution to journalArticle

DNA extraction approaches substantially influence the assessment of the human breast milk microbiome

Douglas, C. A., Ivey, K. L., Papanicolas, L. E., Best, K. P., Muhlhausler, B. S. & Rogers, G. B., 10 Jan 2020, In : Scientific Reports. 10, 1, p. 123

Research output: Contribution to journalArticle

Effects of aging on the motor, cognitive and affective behaviors, neuroimmune responses and hippocampal gene expression

Singhal, G., Morgan, J., Jawahar, M. C., Corrigan, F., Jaehne, E. J., Toben, C., Breen, J., Pederson, S. M., Manavis, J., Hannan, A. J. & Baune, B. T., 6 Apr 2020, In : Behavioural Brain Research. 383, 112501.

Research output: Contribution to journalArticle

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D

Kennedy, S. A., Jarboui, M-A., Srihari, S., Raso, C., Bryan, K., Dernayka, L., Charitou, T., Bernal-Llinares, M., Herrera-Montavez, C., Krstic, A., Matallanas, D., Kotlyar, M., Jurisica, I., Curak, J., Wong, V., Stagljar, I., LeBihan, T., Imrie, L., Pillai, P., Lynn, M. A. & 21 othersFasterius, E., Al-Khalili Szigyarto, C., Breen, J., Kiel, C., Serrano, L., Rauch, N., Rukhlenko, O., Kholodenko, B. N., Iglesias-Martinez, L. F., Ryan, C. J., Pilkington, R., Cammareri, P., Sansom, O., Shave, S., Auer, M., Horn, N., Klose, F., Ueffing, M., Boldt, K., Lynn, D. J. & Kolch, W., 24 Jan 2020, In : Nature communications. 11, 1, p. 499

Research output: Contribution to journalArticle

Functional screening of GATOR1 complex variants reveals a role for mTORC1 deregulation in FCD and focal epilepsy

Dawson, R. E., Nieto Guil, A. F., Robertson, L., Piltz, S., Hughes, J. N. & Thomas, P., 1 Feb 2020, In : Neurobiology of Disease. 134, 104640.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Histone deacetylases 1 and 2 inhibition suppresses cytokine production and osteoclast bone resorption in vitro

Algate, K., Haynes, D., Fitzsimmons, T., Romeo, O., Wagner, F., Holson, E., Reid, R., Fairlie, D., Bartold, P. & Cantley, M., 1 Jan 2020, In : Journal of Cellular Biochemistry. 121, 1, p. 244-258 15 p.

Research output: Contribution to journalArticle

Interrogating the Grainyhead-like 2 (Grhl2) genomic locus identifies an enhancer element that regulates palatogenesis in mouse

de Vries, M., Carpinelli, M., Rutland, E., Hatzipantelis, A., Partridge, D., Auden, A., Anderson, P., De Groef, B., Wu, H., Osterwalder, M., Visel, A., Jane, S. M. & Dworkin, S., 15 Mar 2020, In : Developmental Biology. 459, 2, p. 194-203 10 p.

Research output: Contribution to journalArticle

Lipogenic effects of androgen signaling in normal and malignant prostate

Mah, C. Y., Nassar, Z., Swinnen, J. V. & Butler, L., 1 Jan 2020, In : Asian Journal of Urology.

Research output: Contribution to journalReview article

Multidrug adaptive resistance of Pseudomonas aeruginosa swarming cells

Coleman, S. R., Blimkie, T., Falsafi, R. & Hancock, R., 1 Jan 2020, In : Antimicrobial Agents and Chemotherapy. 64, 3, e01999-19.

Research output: Contribution to journalArticle

Respiratory Viruses Cause Late Morbidity in Recipients of Hematopoietic Stem Cell Transplantation

Marinelli, T., Wee, L. Y., Rowe, E., Chhetri, R., Friel, O., Higgins, G., Bardy, P., Singhal, D., Pradhan, A., Crawford, L. & Hiwase, D. K., 1 Jan 2020, In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Screening for deficits using the G8 and VES-13 in older patients with Myelodysplastic syndromes

Molga, A., Wall, M., Wee, L. Y., Chhetri, R., Singhal, D., Singhal, N., To, L. B., Shakib, S., To, T. & Hiwase, D., 1 Jan 2020, In : Journal of Geriatric Oncology. 11, 1, p. 128-130 3 p.

Research output: Contribution to journalLetter

The effect of co-occurring lesions on leukaemogenesis and drug response in T-ALL and ETP-ALL

Tavakoli Shirazi, P., Eadie, L., Heatley, S., Hughes, T., Yeung, D. & White, D., 18 Feb 2020, In : British Journal of Cancer. 122, 4, p. 455-464 10 p.

Research output: Contribution to journalReview article

The gene encoding the ketogenic enzyme HMGCS2 displays a unique expression during gonad development in mice

Bagheri-Fam, S., Chen, H., Wilson, S., Ayers, K., Hughes, J., Sloan-Bena, F., Calvel, P., Robevska, G., Puisac, B., Kusz-Zamelczyk, K., Gimelli, S., Spik, A., Jaruzelska, J., Warenik-Szymankiewicz, A., Faradz, S., Nef, S., Pié, J., Thomas, P., Sinclair, A. & Wilhelm, D., 1 Jan 2020, In : PloS one. 15, 1, e0227411.

Research output: Contribution to journalArticle

The phosphatidylethanolamine biosynthesis pathway provides a new target for cancer chemotherapy

Guan, Y., Chen, X., Wu, M., Zhu, W., Arslan, A., Takeda, S., Nguyen, M. H., Majeti, R., Thomas, D., Zheng, M. & Peltz, G., 1 Apr 2020, In : Journal of Hepatology. 72, 4, p. 746-760 15 p.

Research output: Contribution to journalArticle

Twist-1 is upregulated by NSD2 and contributes to tumour dissemination and an epithelial-mesenchymal transition-like gene expression signature in t(4;14)-positive multiple myeloma

Cheong, C. M., Mrozik, K. M., Hewett, D., Bell, E., Panagopoulos, V., Noll, J., Licht, J. D., Gronthos, S., Zannettino, A. & Vandyke, K., 10 Apr 2020, In : Cancer Letters. 475, p. 99-108 10 p.

Research output: Contribution to journalArticle

2019

Acute colitis drives tolerance by persistently altering the epithelial barrier and innate and adaptive immunity

Wardill, H. R., Choo, J., Dmochowska, N., Mavrangelos, C., Campaniello, M. A., Bowen, J. M., Rogers, G. & Hughes, P. A., 18 Jun 2019, In : Inflammatory bowel diseases. 25, 7, p. 1196-1207 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A genome-wide knockout screen in human macrophages idetified host factors modulating Salmonella infection

Yeung, A. T. Y., Choi, Y. H., Lee, A. H. Y., Hale, C., Ponstingl, H., Pickard, D., Goulding, D., Thomas, M., Gill, E., Kim, J. K., Bradley, A., Hancock, R. & Dougana, G., 1 Jan 2019, In : mBio. 10, 5, e02169-19.

Research output: Contribution to journalArticle

A lipidic delivery system of a triple vaccine adjuvant enhances mucosal immunity following nasal administration in mice

Wasan, E. K., Syeda, J., Strom, S., Cawthray, J., Hancock, R., Wasan, K. M. & Gerdts, V., 7 Mar 2019, In : Vaccine. 37, 11, p. 1503-1515 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Alpha-Blockers as colorectal cancer chemopreventive: Findings from a case-control study, human cell cultures, and in vivo preclinical testing

Suzuki, N., Niikura, R., Ihara, S., Hikiba, Y., Kinoshita, H., Higashishima, N., Hayakawa, Y., Yamada, A., Hirata, Y., Nakata, R., Okamoto, M., Sano, M., Kushiyama, A., Suzuki Ichinose, M., Woods, S., Worthley, D., Iwamoto, Y. & Koike, K., 1 Mar 2019, In : Cancer Prevention Research. 12, 3, p. 185-194 10 p.

Research output: Contribution to journalArticle

An analysis of a multiple biomarker panel to better predict prostate cancer metastasis after radical prostatectomy

Zhang, A. Y., Chiam, K., Haupt, Y., Fox, S., Birch, S., Tilley, W., Butler, L. M., Knudsen, K., Comstock, C., Rasiah, K., Grogan, J., Mahon, K. L., Bianco-Miotto, T., Ricciardelli, C., Böhm, M., Henshall, S., Delprado, W., Stricker, P., Horvath, L. G. & Kench, J. G., 1 Mar 2019, In : International Journal of Cancer. 144, 5, p. 1151-1159 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A network analysis of biomarkers for type 2 diabetes

Huang, T., Glass, K., Zeleznik, O. A., Kang, J. H., Ivey, K., Sonawane, A. R., Birmann, B. M., Hersh, C. P., Hu, F. B. & Tworoger, S. S., 1 Feb 2019, In : Diabetes. 68, 2, p. 281-290 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A niche-dependent myeloid transcriptome signature defines dormant myeloma cells

Khoo, W. H., Ledergor, G., Weiner, A., Roden, D. L., Terry, R. L., McDonald, M. M., Chai, R. C., De Veirman, K., Owen, K. L., Opperman, K. S., Vandyke, K., Clark, J. R., Seckinger, A., Kovacic, N., Nguyen, A., Mohanty, S. T., Pettitt, J. A., Xiao, Y., Corr, A. P., Seeliger, C. & 14 othersNovotny, M., Lasken, R. S., Nguyen, T. V., Oyajobi, B. O., Aftab, D., Swarbrick, A., Parker, B., Hewett, D., Hose, D., Vanderkerken, K., Zannettino, A., Amit, I., Phan, T. G. & Croucher, P. I., 4 Jul 2019, In : Blood. 134, 1, p. 30-43 14 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Application of machine learning techniques for creating urban microbial fingerprints

Ryan, F., 16 Aug 2019, In : Biology Direct. 14, 1, 13.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Asciminib in chronic myeloid leukemia after Abl kinase inhibitor failure

Hughes, T., Mauro, M. J., Cortes, J. E., Minami, H., Rea, D., DeAngelo, D. J., Breccia, M., Goh, Y. T., Talpaz, M., Hochhaus, A., Coutre, P. L., Ottmann, O., Heinrich, M. C., Steegmann, J. L., Deininger, M. W. N., Janssen, J. J. W. M., Mahon, F. X., Minami, Y., Yeung, D., Ross, D. & 10 othersTallman, M. S., Park, J. H., Druker, B. J., Hynds, D., Duan, Y., Meille, C., Hourcade-Potelleret, F., Vanasse, K. G., Lang, F. & Kim, D. W., 12 Dec 2019, In : New England Journal of Medicine. 381, 24, p. 2315-2326 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
3 Citations (Scopus)

Aurein-Derived Antimicrobial Peptides Formulated with Pegylated Phospholipid Micelles to Target Methicillin-Resistant Staphylococcus aureus Skin Infections

Kumar, P., Pletzer, D., Haney, E. F., Rahanjam, N., Cheng, J. T. J., Yue, M., Aljehani, W., Hancock, R., Kizhakkedathu, J. N. & Straus, S. K., 8 Mar 2019, In : ACS Infectious Diseases. 5, 3, p. 443-453 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Autosomal dominant nanophthalmos and high hyperopia associated with a C-terminal frameshift variant in MYRF

Siggs, O. M., Souzeau, E., Breen, J., Qassim, A., Zhou, T., Dubowsky, A., Ruddle, J. B. & Craig, J. E., 1 Jan 2019, In : Molecular Vision. 25, p. 527-534 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A Y-chromosome shredding gene drive for controlling pest vertebrate populations

Prowse, T. A., Adikusuma, F., Cassey, P., Thomas, P. & Ross, J. V., 1 Feb 2019, In : eLife. 8, e41873.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Azacitidine with or without lenalidomide in higher risk myelodysplastic syndrome & low blast acute myeloid leukemia

Kenealy, M., Hertzberg, M., Benson, W., Taylor, K., Cunningham, I., Stevenson, W., Hiwase, D., Eek, R., Zantomio, D., Jong, S., Wall, M., Blombery, P., Gerber, T., Debrincat, M., Zannino, D. & Seymour, J. F., 31 Mar 2019, In : Haematologica. 104, 4, p. 700-709 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Bacterial viability in faecal transplants: Which bacteria survive?

Papanicolas, L. E., Choo, J., Wang, Y., Leong, L. E. X., Costello, S. P., Gordon, D. L., Wesselingh, S. & Rogers, G., 1 Mar 2019, In : EBioMedicine. 41, p. 509-516 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Barriers and opportunities experienced by staff when implementing infection prevention and control guidelines during labour and delivery in health care facilities in Nigeria

Buxton, H., Flynn, E., Oluyinka, O., Cumming, O., EstevesMills, J., Shiras, T., Sara, S. & Dreibelbis, R., 5 Aug 2019, In : Journal of Hospital Infection.

Research output: Contribution to journalArticle

Biomineralization of platinum by escherichia coli

Shar, S. S., Reith, F., Shahsavari, E., Adetutu, E., Nurulita, Y., Al-Hothaly, K., Haleyur, N. & Ball, A. S., 1 Apr 2019, In : Metals. 9, 4, 407.

Research output: Contribution to journalArticle

1 Citation (Scopus)
1 Citation (Scopus)

B Part of It study: a longitudinal study to assess carriage of Neisseria meningitidis in first year university students in South Australia

McMillan, M., Walters, L., Mark, T., Lawrence, A., Leong, L. E. X., Sullivan, T., Rogers, G., Andrews, R. M. & Marshall, H. S., 3 Apr 2019, In : Human Vaccines and Immunotherapeutics. 15, 4, p. 987-994 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Cancer-associated fibroblasts—heroes or villains?

Gieniec, K. A., Butler, L., Worthley, D. & Woods, S. L., 13 Aug 2019, In : British Journal of Cancer. 121, 4, p. 293-302 10 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

Cancer-associated fibroblasts in gastrointestinal cancer

Kobayashi, H., Enomoto, A., Woods, S., Burt, A. D., Takahashi, M. & Worthley, D., 1 May 2019, In : Nature Reviews Gastroenterology and Hepatology. 16, 5, p. 282-295 14 p.

Research output: Contribution to journalReview article

18 Citations (Scopus)

Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set

del-Toro, N., Duesbury, M., Koch, M., Perfetto, L., Shrivastava, A., Ochoa, D., Wagih, O., Piñero, J., Kotlyar, M., Pastrello, C., Beltrao, P., Furlong, L. I., Jurisica, I., Hermjakob, H., Orchard, S., Porras, P., Khadake, J., Meldal, B., Panni, S., Thorneycroft, D. & 23 othersvan Roey, K., Abbani, S., Salwinski, L., Pellegrini, M., Iannuccelli, M., Licata, L., Cesareni, G., Roechert, B., Bridge, A., Ammari, M. G., McCarthy, F., Broackes-Carter, F., Campbell, N. H., Melidoni, A. N., Rodriguez-Lopez, M., Lovering, R. C., Jagannathan, S., Chen, C., Lynn, D. J., Ricard-Blum, S., Mahadevan, U., Raghunath, A. & authors, IME. C. C., 2 Jan 2019, In : Nature Communications. 10, 1

Research output: Contribution to journalArticle

7 Citations (Scopus)

Carotid Artery Calcification on Orthopantomograms (CACO Study) – is it indicative of carotid stenosis?

Constantine, S., Roach, D., Liberali, S., Kiermeier, A., Sarkar, P., Jannes, J., Sambrook, P., Anderson, P. & Beltrame, J., 1 Mar 2019, In : Australian Dental Journal. 64, 1, p. 4-10 7 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Case report: Identification of intra-laboratory blood culture contamination with Staphylococcus aureus by whole genome sequencing

Ashokan, A., Papanicolas, L. E., Leong, L. E. X., Theodossi, M., Daniel, S., Wesselingh, S., Rogers, G. & Gordon, D. L., 1 Aug 2019, In : Diagnostic Microbiology and Infectious Disease. 94, 4, p. 331-333 3 p.

Research output: Contribution to journalArticle

CD96 Is an Immune Checkpoint That Regulates CD8 + T-cell Antitumor Function

Mittal, D., Lepletier, A., Madore, J., Aguilera, A. R., Stannard, K., Blake, S., Whitehall, V. L. J., Liu, C., Bettington, M. L., Takeda, K., Long, G. V., Scolyer, R. A., Lan, R., Siemers, N., Korman, A., Teng, M. W. L., Johnston, R. J., Dougall, W. C. & Smyth, M. J., 1 Apr 2019, In : Cancer Immunology Research. 7, 4, p. 559-571 13 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Ceasing exercise induces depression-like, anxiety-like, and impaired cognitive-like behaviours and altered hippocampal gene expression

Morgan, J. A., Singhal, G., Corrigan, F., Jaehne, E. J., Jawahar, M. C., Breen, J., Pederson, S. & Baune, B. T., 1 May 2019, In : Brain Research Bulletin. 148, p. 118-130 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Changes in the Composition of the Gut Microbiota and the Blood Transcriptome in Preterm Infants at Less than 29 Weeks Gestation Diagnosed with Bronchopulmonary Dysplasia

Ryan, F., Drew, D. P., Douglas, C., Leong, L. E. X., Moldovan, M., Lynn, M., Fink, N., Sribnaia, A., Penttila, I., McPhee, A. J., Collins, C., Makrides, M., Gibson, R., Rogers, G. & Lynn, D., 29 Oct 2019, In : mSystems. 4, 5, e00484.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Changing incidence of myeloproliferative neoplasms in Australia, 2003-2014

Baade, P. D., Ross, D., Anderson, L. A., Forsyth, C. & Fritschi, L., 1 Apr 2019, In : American Journal of Hematology. 94, 4, p. E107-E109

Research output: Contribution to journalLetter

Characterization of host responses during pseudomonas aeruginosa acute infection in the lungs and blood and after treatment with the synthetic immunomodulatory peptide IDR-1002

Wuerth, K., Lee, A. H. Y., Falsafi, R., Gill, E. E. & Hancock, R., 1 Jan 2019, In : Infection and Immunity. 87, 1, e00661.

Research output: Contribution to journalArticle

4 Citations (Scopus)