Molecular Imaging And Therapy Research Unit

Research Output 2011 2019

2019

Analogues of desferrioxamine B (DFOB) with new properties and new functions generated using precursor-directed biosynthesis

Telfer, T. J., Richardson-Sanchez, T., Gotsbacher, M. P., Nolan, K. P., Tieu, W. & Codd, R., 1 Jun 2019, In : BioMetals. 32, 3, p. 395-408 14 p.

Research output: Contribution to journalArticle

Biomimetic synthetic studies on meroterpenoids from the marine sponge Aka coralliphaga: Divergent total syntheses of siphonodictyal B, liphagal and corallidictyals A–D

Kuan, K., Markwell-Heys, A. W., Cruickshank, M. C., Tran, D. P., Adlington, R. M., Baldwin, J. E. & George, J. H., 15 Jun 2019, In : Bioorganic and Medicinal Chemistry. 27, 12, p. 2449-2465 17 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Immuno-PET of innate immune markers CD11b and IL-1b detects inflammation in murine colitis

Dmochowska, N., Tieu, W., Keller, M. D., Wardill, H. R., Mavrangelos, C., Campaniello, M. A., Takhar, P. & Hughes, P., 1 Jun 2019, In : Journal of Nuclear Medicine. 60, 6, p. 858-863 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Rapid and automated production of [68Ga]gallium chloride and [68Ga]Ga-DOTA-TATE on a medical cyclotron

Tieu, W., Hollis, C. A., Kuan, K., Takhar, P., Stuckings, M., Spooner, N. & Malinconico, M., 1 Jul 2019, In : Nuclear Medicine and Biology. 74-75, p. 12-18 7 p.

Research output: Contribution to journalArticle

Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads

Lee, K. J., Tieu, W., Blanco-Rodriguez, B., Paparella, A. S., Yu, J., Hayes, A., Feng, J., Marshall, A. C., Noll, B., Milne, R., Cini, D., Wilce, M. C. J., Booker, G. W., Bruning, J. B., Polyak, S. W. & Abell, A. D., 21 Aug 2019, In : ACS Chemical Biology.

Research output: Contribution to journalArticle

2018

18-Fluoride labeled sodium fluoride positron emission tomography with computer tomography: the impact of pretreatment staging in intermediate- and high-risk prostate cancer

Harley, S. JD., Hoffmann, R., Bartholomeusz, D., Sutherland, P., Chatterton, B., Kitchener, M., Takhar, P., Tsopelas, C., Fuller, A., Wells, R., Singh-Rai, R. & Bolt, J., 1 Jun 2018, In : Prostate International. 6, 2, p. 50-54 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Crystal structure of highly glycosylated human leukocyte elastase in complex with an S200 site binding inhibitor

Hochscherf, J., Pietsch, M., Tieu, W., Kuan, K., Abell, A. D., Gütschow, M. & Niefind, K., 1 Aug 2018, In : Acta Crystallographica Section F: Structural Biology Communications. 74, 8, p. 480-489 10 p.

Research output: Contribution to journalArticle

Immuno-PET of innate immune markers CD11b and 1IL-1β detect inflammation in murine colitis.

Dmochowska, N., Tieu, W., Keller, M., Wardill, H. R., Mavrangelos, C., Campaniello, M. A., Takhar, P. & Hughes, P., 2018, In : Journal of Nuclear Medicine. JNUMED/2018/219287.

Research output: Contribution to journalArticle

In vivo PET of innate immune responses in murine DSS colitis

Dmochowska, N., Campaniello, M. A., Mavrangelos, C., Wardill, H. R., Keller, M., Tieu, W. & Hughes, P., 2018.

Research output: Contribution to conferencePoster

2017

18F-FDG-PET: A non-invasive tool for imaging colitis: Australasian Society for Immunology Annual Scientific Meeting

Dmochowska, N., Campaniello, M. A., Mavrangelos, C., Wardill, H., Keller, M., Tieu, W. & Hughes, D. P., Nov 2017.

Research output: Contribution to conferencePoster

18F-FDG-PET: A non-invasive tool for imaging colitis

Dmochowska, N., Campaniello, M. A., Mavrangelos, C., Wardill, H. R., Keller, M., Tieu, W. & Hughes, P., 2017.

Research output: Contribution to conferencePoster

18F-FDG-PET: A non-invasive tool for imaging colitis

Dmochowska, N., Campaniello, M. A., Mavrangelos, C., Wardill, H. R., Keller, M., Tieu, W. & Hughes, P., 2017.

Research output: Contribution to conferencePoster

3 Citations (Scopus)

Dimeric and trimeric homo- and heteroleptic hydroxamic acid macrocycles formed using mixed-ligand Fe(III)-based metal-templated synthesis

Sresutharsan, A., Tieu, W., Richardson-Sanchez, T., Soe, C. Z. & Codd, R., 1 Dec 2017, In : Journal of Inorganic Biochemistry. 177, p. 344-351 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Exploiting the biosynthetic machinery of: Streptomyces pilosus to engineer a water-soluble zirconium(IV) chelator

Richardson-Sanchez, T., Tieu, W., Gotsbacher, M. P., Telfer, T. J. & Codd, R., 2017, In : Organic and Biomolecular Chemistry. 15, 27, p. 5719-5730 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Reverse Biosynthesis: Generating Combinatorial Pools of Drug Leads from Enzyme-Mediated Fragmentation of Natural Products

Richardson-Sanchez, T., Tieu, W. & Codd, R., 16 Feb 2017, In : ChemBioChem. 18, 4, p. 368-373 6 p.

Research output: Contribution to journalArticle

2016
3 Citations (Scopus)

A biomimetic synthetic approach to the frondosins

Kuan, K., Hirschvogel, A. M. C. & George, J. H., 1 Jan 2016, In : Australian Journal of Chemistry. 69, 12, p. 1420-1423 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

GEANT4 simulation of cyclotron radioisotope production in a solid target

Poignant, F., Penfold, S., Asp, J., Takhar, P. & Jackson, P., 1 May 2016, In : Physica Medica. 32, 5, p. 728-734 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2015
12 Citations (Scopus)
25 Citations (Scopus)

Total Synthesis and Structure Revision of (-)-Siphonodictyal B and Its Biomimetic Conversion into (+)-Liphagal

Markwell-Heys, A. W., Kuan, K. & George, J. H., 21 Aug 2015, In : Organic Letters. 17, 17, p. 4228-4231 4 p.

Research output: Contribution to journalArticle

2014
4 Citations (Scopus)

Biomimetic total synthesis of (±)-yezo'otogirin A

Lam, H. C., Kuan, K. & George, J. H., 28 Apr 2014, In : Organic and Biomolecular Chemistry. 12, 16, p. 2519-2522 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Heterocyclic acyl-phosphate bioisostere-based inhibitors of Staphylococcus aureus biotin protein ligase

Tieu, W., Jarrad, A. M., Paparella, A. S., Keeling, K. A., Soares Da Costa, T. P., Wallace, J. C., Booker, G. W., Polyak, S. W. & Abell, A. D., 1 Oct 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 19, p. 4689-4693 5 p.

Research output: Contribution to journalArticle

2013
16 Citations (Scopus)

Characterisation of a real-time fibre-coupled beryllium oxide (BeO) luminescence dosimeter in X-ray beams

Santos, A. M. C., Mohammadi, M., Asp, J., Monro, T. M. & Afshar V., S., 1 Jun 2013, In : Radiation Measurements. 53-54, p. 1-7 7 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Optimising in situ click chemistry: The screening and identification of biotin protein ligase inhibitors

Tieu, W., Soares Da Costa, T. P., Yap, M. Y., Keeling, K. L., Wilce, M. C. J., Wallace, J. C., Booker, G. W., Polyak, S. W. & Abell, A. D., Sep 2013, In : Chemical Science. 4, 9, p. 3533-3537 5 p.

Research output: Contribution to journalArticle

2012
31 Citations (Scopus)

5-Benzylidenerhodanine and 5-benzylidene-2-4-thiazolidinedione based antibacterials

Zvarec, O., Polyak, S. W., Tieu, W., Kuan, K., Dai, H., Pedersen, D. S., Morona, R., Zhang, L., Booker, G. W. & Abell, A. D., 15 Apr 2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 8, p. 2720-2722 3 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Biotin analogues with antibacterial activity are potent inhibitors of biotin protein ligase

Soares Da Costa, T. P., Tieu, W., Yap, M. Y., Zvarec, O., Bell, J. M., Turnidge, J. D., Wallace, J. C., Booker, G. W., Wilce, M. C. J., Abell, A. D. & Polyak, S. W., 14 May 2012, In : ACS Medicinal Chemistry Letters. 3, 6, p. 509-514 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Evaluation of physician eye lens doses during permanent seed implant brachytherapy for prostate cancer

Penfold, S. N., Marcu, L., Lawson, J. M. & Asp, J., 1 Sep 2012, In : Journal of Radiological Protection. 32, 3, p. 339-347 9 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Selective inhibition of biotin protein ligase from Staphylococcus aureus

Soares Da Costa, T. P., Tieu, W., Yap, M. Y., Pendini, N. R., Polyak, S. W., Pedersen, D. S., Morona, R., Turnidge, J. D., Wallace, J. C., Wilce, M. C. J., Booker, G. W. & Abell, A. D., 18 May 2012, In : Journal of Biological Chemistry. 287, 21, p. 17823-17832 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Synthesis of a liphagal-frondosin c hybrid and speculation on the biosynthesis of the frondosins

Pepper, H. P., Kuan, K. & George, J. H., 16 Mar 2012, In : Organic Letters. 14, 6, p. 1524-1527 4 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Total synthesis of (+)-aureol

Kuan, K., Pepper, H. P., Bloch, W. M. & George, J. H., 21 Sep 2012, In : Organic Letters. 14, 18, p. 4710-4713 4 p.

Research output: Contribution to journalArticle

2011
60 Citations (Scopus)

Diamond in tellurite glass: A new medium for quantum information

Henderson, M. R., Gibson, B. C., Ebendorff-Heidepriem, H., Kuan, K., Afshar V., S., Orwa, J. O., Aharonovich, I., Tomljenovic-Hanic, S., Greentree, A. D., Prawer, S. & Monro, T. M., 5 Jul 2011, In : Advanced Materials. 23, 25, p. 2806-2810 5 p.

Research output: Contribution to journalArticle

Fabrication of depressed cladding waveguide Bragg-gratings in rare-earth doped heavy-metal fluoride glass

Gross, S., Lancaster, D. G., Ebendorff-Heidepriem, H., Kuan, K., Monro, T. M., Withford, M. J. & Fuerbach, A., 6 Sep 2011, 2011 Conference on Lasers and Electro-Optics Europe and 12th European Quantum Electronics Conference, CLEO EUROPE/EQEC 2011. 5943324

Research output: Chapter in Book/Report/Conference proceedingConference contribution

30 Citations (Scopus)

New cholesterol esterase inhibitors based on rhodanine and thiazolidinedione scaffolds

Heng, S., Tieu, W., Hautmann, S., Kuan, K., Pedersen, D. S., Pietsch, M., Gütschow, M. & Abell, A. D., 15 Dec 2011, In : Bioorganic and Medicinal Chemistry. 19, 24, p. 7453-7463 11 p.

Research output: Contribution to journalArticle

Single photon emission from nanodiamond in tellurite glass

Gibson, B. C., Henderson, M. R., Ebendorff-Heidepriem, H., Kuan, K., Afshar, V. S., Orwa, J. O., Aharonovich, I., Tomljenovic-Hanic, S., Prawer, S., Monro, T. M. & Greentree, A. D., 2011, International Quantum Electronics Conference, IQEC 2011. p. 721-722 2 p. 6193950

Research output: Chapter in Book/Report/Conference proceedingConference contribution