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2019

Alpha-Blockers as colorectal cancer chemopreventive: Findings from a case-control study, human cell cultures, and in vivo preclinical testing

Suzuki, N., Niikura, R., Ihara, S., Hikiba, Y., Kinoshita, H., Higashishima, N., Hayakawa, Y., Yamada, A., Hirata, Y., Nakata, R., Okamoto, M., Sano, M., Kushiyama, A., Suzuki Ichinose, M., Woods, S., Worthley, D., Iwamoto, Y. & Koike, K., 1 Mar 2019, In : Cancer Prevention Research. 12, 3, p. 185-194 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Meflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis

Mizutani, Y., Kobayashi, H., Iida, T., Asai, N., Masamune, A., Hara, A., Esaki, N., Ushida, K., Mii, S., Shiraki, Y., Ando, K., Weng, L., Ishihara, S., Ponik, S. M., Conklin, M. W., Haga, H., Nagasaka, A., Miyata, T., Matsuyama, M., Kobayashi, T. & 11 othersFujii, T., Yamada, S., Yamaguchi, J., Wang, T., Woods, S., Worthley, D., Shimamura, T., Fujishiro, M., Hirooka, Y., Enomoto, A. & Takahashi, M., 15 Oct 2019, In : Cancer Research. 79, 20, p. 5367-5381 15 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Mouse Model for Cholangiocarcinoma from Peribiliary Glands

Nakagawa, H., Suzuki, N. & Koike, K., 1 Jan 2019, In : Methods in molecular biology (Clifton, N.J.). 1905, p. 237-245 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Diagnostic capability of colon capsule endoscopy for advanced colorectal cancer: A pilot study

Ota, Y., Yamada, A., Kobayashi, Y., Niikura, R., Shimpoh, T., Narita, A., Yoshida, S., Suzuki, N., Watabe, H., Hirata, Y., Ishihara, S., Sunami, E., Watanabe, T. & Koike, K., 1 Jun 2018, In : Gastroenterological Endoscopy. 60, 6, p. 1240-1248 9 p.

Research output: Contribution to journalArticle

Distinct chemopreventive effects of aspirin in diffuse and intestinal-type gastric cancer

Niikura, R., Hayakawa, Y., Hirata, Y., Konishi, M., Suzuki, N., Ihara, S., Yamada, A., Ushiku, T., Fujishiro, M., Fukayama, M. & Koike, K., 1 May 2018, In : Cancer Prevention Research. 11, 5, p. 279-286 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Overexpression of HER2 in the pancreas promotes development of intraductal papillary mucinous neoplasms in mice

Shibata, W., Kinoshita, H., Hikiba, Y., Sato, T., Ishii, Y., Sue, S., Sugimori, M., Suzuki, N., Sakitani, K., Ijichi, H., Mori, R., Endo, I. & Maeda, S., 1 Dec 2018, In : Scientific Reports. 8, 1, 6150.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

c-Jun N-terminal kinase in pancreatic tumor stroma augments tumor development in mice

Sato, T., Shibata, W., Hikiba, Y., Kaneta, Y., Suzuki, N., Ihara, S., Ishii, Y., Sue, S., Kameta, E., Sugimori, M., Yamada, H., Kaneko, H., Sasaki, T., Ishii, T., Tamura, T., Kondo, M. & Maeda, S., 1 Nov 2017, In : Cancer Science. 108, 11, p. 2156-2165 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Diagnostic capability of colon capsule endoscopy for advanced colorectal cancer: A pilot study

Ota, Y., Yamada, A., Kobayashi, Y., Niikura, R., Shimpoh, T., Narita, A., Yoshida, S., Suzuki, N., Watabe, H., Hirata, Y., Ishihara, S., Sunami, E., Watanabe, T. & Koike, K., 1 Sep 2017, In : Digestive Endoscopy. 29, 6, p. 695-701 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

First-Line Helicobacter pylori Eradication with Vonoprazan, Clarithromycin, and Metronidazole in Patients Allergic to Penicillin

Sue, S., Suzuki, N., Shibata, W., Sasaki, T., Yamada, H., Kaneko, H., Tamura, T., Ishii, T., Kondo, M. & Maeda, S., 1 Jan 2017, In : Gastroenterology Research and Practice. 2017, 2019802.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Prevalence of pks-positive Escherichia coli in Japanese patients with or without colorectal cancer

Shimpoh, T., Hirata, Y., Ihara, S., Suzuki, N., Kinoshita, H., Hayakawa, Y., Ota, Y., Narita, A., Yoshida, S., Yamada, A. & Koike, K., 12 Jun 2017, In : Gut Pathogens. 9, 1, 35.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2016

Gastric metaplasia induced by Helicobacter pylori is associated with enhanced SOX9 expression via interleukin-1 signaling

Serizawa, T., Hirata, Y., Hayakawa, Y., Suzuki, N., Sakitani, K., Hikiba, Y., Ihara, S., Kinoshita, H., Nakagawa, H., Tateishi, K. & Koike, K., 1 Jan 2016, In : Infection and Immunity. 84, 2, p. 562-572 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2015

Inhibition of autophagy exerts anti-colon cancer effects via apoptosis induced by p53 activation and ER stress

Sakitani, K., Hirata, Y., Hikiba, Y., Hayakawa, Y., Ihara, S., Suzuki, H., Suzuki, N., Serizawa, T., Kinoshita, H., Sakamoto, K., Nakagawa, H., Tateishi, K., Maeda, S., Ikenoue, T., Kawazu, S. & Koike, K., 24 Oct 2015, In : BMC Cancer. 15, 1, 795.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein

Suzuki, N., Murata-Kamiya, N., Yanagiya, K., Suda, W., Hattori, M., Kanda, H., Bingo, A., Fujii, Y., Maeda, S., Koike, K. & Hatakeyama, M., 6 May 2015, In : Scientific Reports. 5, 10024.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma

Aoude, L. G., Pritchard, A. L., Robles-Espinoza, C. D., Wadt, K., Harland, M., Choi, J., Gartside, M., Quesada, V., Johansson, P., Palmer, J. M., Ramsay, A. J., Zhang, X., Jones, K., Symmons, J., Holland, E. A., Schmid, H., Bonazzi, V., Woods, S., Dutton-Regester, K., Stark, M. S. & 19 othersSnowden, H., Van Doorn, R., Montgomery, G. W., Martin, N. G., Keane, T. M., López-Otín, C., Gerdes, A. M., Olsson, H., Ingvar, C., Borg, A., Gruis, N. A., Trent, J. M., Jönsson, G., Bishop, D. T., Mann, G. J., Newton-Bishop, J. A., Brown, K. M., Adams, D. J. & Hayward, N. K., 1 Feb 2015, In : Journal of the National Cancer Institute. 107, 2

Research output: Contribution to journalArticle

75 Citations (Scopus)
2013

NRAS and BRAF mutations in cutaneous melanoma and the association with MC1R genotype: Findings from Spanish and Austrian populations

Hacker, E., Nagore, E., Cerroni, L., Woods, S., Hayward, N. K., Chapman, B., Montgomery, G. W., Soyer, H. P. & Whiteman, D. C., 1 Jan 2013, In : Journal of Investigative Dermatology. 133, 4, p. 1027-1033 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Repair and removal of azoxymethane-induced O6-methylguanine in rat colon by O6-methylguanine DNA methyltransferase and apoptosis

Vrbanac, L., Watson, A. J., Margison, G. P., Le Leu, R. K., Kim, S., Lockett, T. J., Head, R. J., Young, G. P. & Hu, Y., 12 Dec 2013, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 758, 1-2, p. 80-86 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2012

Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

Stark, M. S., Woods, S., Gartside, M. G., Bonazzi, V. F., Dutton-Regester, K., Aoude, L. G., Chow, D., Sereduk, C., Niemi, N. M., Tang, N., Ellis, J. J., Reid, J., Zismann, V., Tyagi, S., Muzny, D., Newsham, I., Wu, Y., Palmer, J. M., Pollak, T., Youngkin, D. & 10 othersBrooks, B. R., Lanagan, C., Schmidt, C. W., Kobe, B., MacKeigan, J. P., Yin, H., Brown, K. M., Gibbs, R., Trent, J. & Hayward, N. K., 1 Feb 2012, In : Nature Genetics. 44, 2, p. 165-169 5 p.

Research output: Contribution to journalArticle

137 Citations (Scopus)
2011

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

Yokoyama, S., Woods, S., Boyle, G. M., Aoude, L. G., MacGregor, S., Zismann, V., Gartside, M., Cust, A. E., Haq, R., Harland, M., Taylor, J. C., Duffy, D. L., Holohan, K., Dutton-Regester, K., Palmer, J. M., Bonazzi, V., Stark, M. S., Symmons, J., Law, M. H., Schmidt, C. & 27 othersLanagan, C., O'Connor, L., Holland, E. A., Schmid, H., Maskiell, J. A., Jetann, J., Ferguson, M., Jenkins, M. A., Kefford, R. F., Giles, G. G., Armstrong, B. K., Aitken, J. F., Hopper, J. L., Whiteman, D. C., Pharoah, P. D., Easton, D. F., Dunning, A. M., Newton-Bishop, J. A., Montgomery, G. W., Martin, N. G., Mann, G. J., Bishop, D. T., Tsao, H., Trent, J. M., Fisher, D. E., Hayward, N. K. & Brown, K. M., 1 Dec 2011, In : Nature. 480, 7375, p. 99-103 5 p.

Research output: Contribution to journalArticle

269 Citations (Scopus)
2010

MiR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma

Swarbrick, A., Woods, S., Shaw, A., Balakrishnan, A., Phua, Y., Nguyen, A., Chanthery, Y., Lim, L., Ashton, L. J., Judson, R. L., Huskey, N., Blelloch, R., Haber, M., Norris, M. D., Lengyel, P., Hackett, C. S., Preiss, T., Chetcuti, A., Sullivan, C. S., Marcusson, E. G. & 3 othersWeiss, W., L'Etoile, N. & Goga, A., 1 Oct 2010, In : Nature Medicine. 16, 10, p. 1134-1140 7 p.

Research output: Contribution to journalArticle

126 Citations (Scopus)
2008

The bHLH/Per-Arnt-Sim transcription factor SIM2 regulates muscle transcript myomesin2 via a novel, non-canonical E-box sequence

Woods, S., Farrall, A., Procko, C. & Whitelaw, M. I., 1 Jun 2008, In : Nucleic acids research. 36, 11, p. 3716-3727 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)