Research Output 2009 2018

2018
18 Citations (Scopus)

Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma

MacGregor, S., Ong, J-S., An, J., Han, X., Zhou, T., Siggs, O. M., Law, M. H., Souzeau, E., Sharma, S., Lynn, D. J., Beesley, J., Sheldrick, B., Mills, R. A., Landers, J., Ruddle, J. B., Graham, S. L., Healey, P. R., White, A. J. R., Casson, R. J., Best, S. & 12 othersGrigg, J. R., Goldberg, I., Powell, J. E., Whiteman, D. C., Radford-Smith, G. L., Martin, N. G., Montgomery, G. W., Burdon, K. P., Mackey, D. A., Gharahkhani, P., Craig, J. E. & Hewitt, A. W., 2018, In : Nature Genetics. 50, 8, p. 1067-1071 5 p.

Research output: Contribution to journalArticle

2016
8 Citations (Scopus)

The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress

Ebrahimie, E., Moussavi Nik, S. H., Newman, M., Van Der Hoek, M. & Lardelli, M., 10 May 2016, In : Journal of Alzheimer's Disease. 52, 2, p. 581-608 28 p.

Research output: Contribution to journalArticle

2015
8 Citations (Scopus)

Characterization of pneumococcal genes involved in bloodstream invasion in a mouse model

Mahdi, L. K., Van Der Hoek, M. B., Ebrahimie, E., Paton, J. C. & Ogunniyi, A. D., 5 Nov 2015, In : PloS one. 10, 11, e0141816.

Research output: Contribution to journalArticle

2014
47 Citations (Scopus)

Differential expression of miR-125a-5p and let-7e predicts the progression and prognosis of non-small cell lung cancer

Zhu, W. Y., Luo, B., An, J., He, J. Y., Chen, D. D., Xu, L. Y., Huang, Y. Y., Liu, X. G., Le, H. B. & Zhang, Y. K., 1 Jan 2014, In : Cancer Investigation. 32, 8, p. 394-401 8 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

MicroRNA signatures in chemotherapy resistant esophageal cancer cell lines

Hummel, R., Sie, C., Watson, D. I., Wang, T., Ansar, A., Michael, M. Z., Van Der Hoek, M., Haier, J. & Hussey, D. J., 1 Jan 2014, In : World Journal of Gastroenterology. 20, 40, p. 14904-14912 9 p.

Research output: Contribution to journalArticle

2013
68 Citations (Scopus)

Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster

Humphreys, K. J., Cobiac, L., Le Leu, R. K., Van der Hoek, M. B. & Michael, M. Z., 1 Jun 2013, In : Molecular Carcinogenesis. 52, 6, p. 459-474 16 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

Neolithic mitochondrial haplogroup H genomes and the genetic origins of Europeans

Brotherton, P., Haak, W., Templeton, J., Brandt, G., Soubrier, J., Jane Adler, C., Richards, S. M., Sarkissian, C. D., Ganslmeier, R., Friederich, S., Dresely, V., Van Oven, M., Kenyon, R., Van Der Hoek, M. B., Korlach, J., Luong, K., Ho, S. Y. W., Quintana-Murci, L., Behar, D. M., Meller, H. & 39 othersAlt, K. W., Cooper, A., Adhikarla, S., Ganesh Prasad, A. K., Pitchappan, R., Varatharajan Santhakumari, A., Balanovska, E., Balanovsky, O., Bertranpetit, J., Comas, D., Martínez-Cruz, B., Melé, M., Clarke, A. C., Matisoo-Smith, E. A., Dulik, M. C., Gaieski, J. B., Owings, A. C., Schurr, T. G., Vilar, M. G., Hobbs, A., Soodyall, H., Javed, A., Parida, L., Platt, D. E., Royyuru, A. K., Jin, L., Li, S., Kaplan, M. E., Merchant, N. C., John Mitchell, R., Renfrew, C., Lacerda, D. R., Santos, F. R., Soria Hernanz, D. F., Spencer Wells, R., Swamikrishnan, P., Tyler-Smith, C., Paulo Vieira, P. & Ziegle, J. S., 20 May 2013, In : Nature communications. 4, 1764.

Research output: Contribution to journalArticle

2012
3 Citations (Scopus)

Genome-wide gene expression profiling identifies overlap with malignant adrenocortical tumours and novel mechanisms of inefficient steroidogenesis in familial ACTH-independent macronodular adrenal hyperplasia

Gagliardi, L., Ling, K. H., Kok, C. H., Carolan, J., Brautigan, P., Kenyon, R., D'Andrea, R. J., Van Der Hoek, M., Hahn, C. N., Torpy, D. J. & Scott, H. S., 1 Jun 2012, In : Endocrine-Related Cancer. 19, 3

Research output: Contribution to journalLetter

38 Citations (Scopus)

Identification of a novel pneumococcal vaccine antigen preferentially expressed during meningitis in mice

Mahdi, L. K., Wang, H., Van Der Hoek, M. B., Paton, J. C. & Ogunniyi, A. D., 1 Jun 2012, In : Journal of Clinical Investigation. 122, 6, p. 2208-2220 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Identification of genes that contribute to the pathogenesis of invasive pneumococcal disease by in vivo transcriptomic analysis

Ogunniyi, A. D., Mahdi, L. K., Trappetti, C., Verhoeven, N., Mermans, D., Van der Hoek, M. B., Plumptre, C. D. & Paton, J. C., 1 Sep 2012, In : Infection and Immunity. 80, 9, p. 3268-3278 11 p.

Research output: Contribution to journalArticle

2011
11 Citations (Scopus)

Autoimmune regulator (AIRE)-deficient CD8 +CD28 low regulatory T lymphocytes fail to control experimental colitis

Pomié, C., Vicente, R., Vuddamalay, Y., Lundgren, B. A., Van Der Hoek, M., Enault, G., Kagan, J., Fazilleau, N., Scott, H. S., Romagnoli, P. & Van Meerwijk, J. P. M., 26 Jul 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 30, p. 12437-12442 6 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Chemotherapy-induced modification of microRNA expression in esophageal cancer

Hummel, R., Wang, T., Watson, D. I., Michael, M. Z., Van Der Hoek, M., Haier, J. & Hussey, D. J., 1 Oct 2011, In : Oncology Reports. 26, 4, p. 1011-1017 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Differential expression of microRNA-1 in dorsal root ganglion neurons

Bastian, I., Tam Tam, S., Zhou, X. F., Kazenwadel, J., Van Der Hoek, M., Michael, M. Z., Gibbins, I. & Haberberger, R. V., 1 Jan 2011, In : Histochemistry and cell biology. 135, 1, p. 37-45 9 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

MicroRNA-143 expression in dorsal root ganglion neurons

Tam Tam, S., Bastian, I., Zhou, X. F., Vander Hoek, M., Michael, M. Z., Gibbins, I. L. & Haberberger, R. V., Nov 2011, In : Cell and Tissue Research. 346, 2, p. 163-173 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

MicroRNA expression profile during adipogenic differentiation in mouse embryonic stem cells

Knelangen, J. M., van der Hoek, M. B., Kong, W. C., Owens, J. A., Fischer, B. & Santos, A. N., 1 May 2011, In : Physiological Genomics. 43, 10, p. 611-620 10 p.

Research output: Contribution to journalArticle

2010
61 Citations (Scopus)

Central role of manganese in regulation of stress responses, physiology, and metabolism in Streptococcus pneumoniae

Ogunniyi, A. D., Mahdi, L. K., Jennings, M. P., McEwan, A. G., McDevitt, C. A., Van Der Hoek, M. B., Bagley, C. J., Hoffmann, P., Gould, K. A. & Paton, J. C., 1 Sep 2010, In : Journal of bacteriology. 192, 17, p. 4489-4497 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Defining the phosphite-regulated transcriptome of the plant pathogen Phytophthora cinnamomi

King, M., Reeve, W., Van Der Hoek, M., Williams, N., McComb, J., O'Brien, P. A. & Hardy, G. E. S. J., 1 Dec 2010, In : Molecular Genetics and Genomics. 284, 6, p. 425-435 11 p.

Research output: Contribution to journalArticle

132 Citations (Scopus)

The VHL-dependent regulation of microRNAs in renal cancer

Neal, C. S., Michael, M. Z., Rawlings, L. H., Van der Hoek, M. B. & Gleadle, J. M., 21 Oct 2010, In : BMC Medicine. 8, 64.

Research output: Contribution to journalArticle

2009
10 Citations (Scopus)

Gene expression microarray analysis of early oxygen-induced retinopathy in the rat

Tea, M., Fogarty, R., Brereton, H. M., Michael, M. Z., Van der Hoek, M. B., Tsykin, A., Coster, D. J. & Williams, K. A., 1 Dec 2009, In : Journal of Ocular Biology, Diseases, and Informatics. 2, 4, p. 190-201 12 p.

Research output: Contribution to journalArticle

223 Citations (Scopus)

MicroRNA-regulated pathways associated with endometriosis

Teague, E. M. C. O., Van Der Hoek, K. H., Van Der Hoek, M. B., Perry, N., Wagaarachchi, P., Robertson, S. A., Print, C. G. & Hull, M. L., 1 Feb 2009, In : Molecular Endocrinology. 23, 2, p. 265-275 11 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

The Interleukin-6 Family Cytokine Interleukin-11 Regulates Homeostatic Epithelial Cell Turnover and Promotes Gastric Tumor Development

Howlett, M., Giraud, A. S., Lescesen, H., Jackson, C. B., Kalantzis, A., Van Driel, I. R., Robb, L., Van der Hoek, M., Ernst, M., Minamoto, T., Boussioutas, A., Oshima, H., Oshima, M. & Judd, L. M., 1 Jan 2009, In : Gastroenterology. 136, 3

Research output: Contribution to journalArticle