Research Output 1987 2019

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2017
6 Citations

Bisphosphonate guidelines for treatment and prevention of myeloma bone disease

Lee, O. L. , Horvath, N. , Lee, C. , Joshua, D. , Ho, J. , Szer, J. , Quach, H. , Spencer, A. , Harrison, S. , Mollee, P. , Roberts, A. W. , Talaulikar, D. , Brown, R. , Augustson, B. , Ling, S. , Jaksic, W. , Gibson, J. , Kalff, A. , Johnston, A. , Kalro, A. & 3 others Ward, C., Prince, H. M. & Zannettino, A. 1 Aug 2017 In : Internal Medicine Journal. 47, 8, p. 938-951 14 p.

Research output: Research - peer-reviewLetter

5 Citations

High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment

Heatley, S. , Sadras, T. , Kok, C. , Nievergall, E. , Quek, K. , Dang, Y. , McClure, B. , Venn, N. C. , Moore, S. , Suttle, J. M. , Law, T. , Ng, A. , Muskovic, W. , Norris, M. , Revesz, T. , Osborn, M. , Moore, S. , Suppiah, R. , Fraser, C. , Alvaro, F. & 7 others Hughes, T., Mullighan, C. G., Marshall, G. M., Dalla Pozza, L., Yeung, D., Sutton, R. & White, D. Dec 2017 In : Haematologica. p. e490-e493

Research output: Research - peer-reviewLetter

3 Citations

miR-155 as a potential target of IL-3 signaling in primary AML cells

Sadras, T., Kok, C. H., Perugini, M., Ramshaw, H. S. & D'Andrea, R. J. 1 Jun 2017 In : Leukemia Research. 57, p. 57-59 3 p.

Research output: Research - peer-reviewLetter

2016
5 Citations

Low incidence of peripheral arterial disease in patients receiving dasatinib in clinical trials

Le Coutre, P. D., Hughes, T. P., Mahon, F. X., Kim, D. W., Steegmann, J. L., Shah, N. P., Gooden, K., Wallis, N. & Cortes, J. E. 1 Jul 2016 In : Leukemia. 30, 7, p. 1593-1596 4 p.

Research output: Research - peer-reviewLetter

4 Citations

Xenograft-directed personalized therapy for a patient with post-transplant relapse of ALL

Trahair, T. N., Lock, R. B., Sutton, R., Sia, K. C. S., Evans, K., Richmond, J., Law, T., Venn, N. C., Irving, J. A., Moore, S., Nievergall, E., Dang, P., Heatley, S. L., White, D. L. & Revesz, T. 1 Sep 2016 In : Bone Marrow Transplantation. 51, 9, p. 1279-1282 4 p.

Research output: Research - peer-reviewLetter

2015
9 Citations

Ponatinib is not transported by ABCB1, ABCG2 or OCT-1 in CML cells

Lu, L., Saunders, V. A., Leclercq, T. M., Hughes, T. P. & White, D. L. 7 Aug 2015 In : Leukemia. 29, 8, p. 1792-1794 3 p.

Research output: Research - peer-reviewLetter

12 Citations

Relapse of BCR-ABL1-like ALL mediated by the ABL1 kinase domain mutation T315I following initial response to dasatinib treatment

Yeung, D. T., Moulton, D. J., Heatley, S. L., Nievergall, E., Dang, P., Braley, J., Branford, S., Moore, S., Mullighan, C. G., Hughes, T. P. & White, D. L. 10 Jan 2015 In : Leukemia. 29, 1, p. 230-232 3 p.

Research output: Research - peer-reviewLetter

2014
3 Citations
2013
19 Citations
12 Citations

Distribution of genomic breakpoints in chronic myeloid leukemia: Analysis of 308 patients

Ross, D. M., O'Hely, M., Bartley, P. A., Dang, P., Score, J., Goyne, J. M., Sobrinho-Simoes, M., Cross, N. C. P., Melo, J. V., Speed, T. P., Hughes, T. P. & Morley, A. A. Oct 2013 In : Leukemia. 27, 10, p. 2105-2107 3 p.

Research output: Research - peer-reviewLetter

13 Citations

GADD45A methylation predicts poor overall survival in acute myeloid leukemia and is associated with IDH1/2 and DNMT3A mutations

Perugini, M., Iarossi, D. G., Kok, C. H., Cummings, N., Diakiw, S. M., Brown, A. L., Danner, S., Bardy, P., Bik To, L., Wei, A. H., Lewis, I. D. & D'Andrea, R. J. Jul 2013 In : Leukemia. 27, 7, p. 1588-1592 5 p.

Research output: Research - peer-reviewLetter

9 Citations

Low GFI1 expression in white blood cells of CP-CML patients at diagnosis is strongly associated with subsequent blastic transformation

Kok, C. H., Watkins, D. B., Leclercq, T., D'Andrea, R. J., Hughes, T. P. & White, D. L. Jun 2013 In : Leukemia. 27, 6, p. 1427-1430 4 p.

Research output: Research - peer-reviewLetter

8 Citations

Methylation of KLF5 contributes to reduced expression in acute myeloid leukaemia and is associated with poor overall survival

Diakiw, S. M., Perugini, M., Kok, C. H., Engler, G. A., Cummings, N., To, L. B., Wei, A. H., Lewis, I. D., Brown, A. L. & D'Andrea, R. J. Jun 2013 In : British Journal of Haematology. 161, 6, p. 884-888 5 p.

Research output: Research - peer-reviewLetter

7 Citations

NPM1 mutations occur rarely or not at all in chronic myeloid leukaemia patients in chronic phase or blast crisis

Watkins, D. B., Hughes, T. P., White, D. L. & D'Andrea, R. J. Feb 2013 In : Leukemia. 27, 2, p. 489-490 2 p.

Research output: Research - peer-reviewLetter

7 Citations
4 Citations

Safety and efficacy of pulsed imatinib with or without G-CSF versus continuous imatinib in chronic phase chronic myeloid leukaemia patients at 5 years follow-up

Gallipoli, P., Stobo, J., Heaney, N., Nicolini, F. E., Clark, R., Wilson, G., Tighe, J., Mclintock, L., Hughes, T., Michor, F., Paul, J., Drummond, M. & Holyoake, T. L. Dec 2013 In : British Journal of Haematology. 163, 5, p. 674-676 3 p.

Research output: Research - peer-reviewLetter

4 Citations

The preferential occurrence of FLT3-TKD mutations in inv(16) AML and impact on survival outcome: A combined analysis of 1053 core-binding factor AML patients

Kok, C. H., Brown, A. L., Perugini, M., Iarossi, D. G., Lewis, I. D. & D'Andrea, R. J. Feb 2013 In : British Journal of Haematology. 160, 4, p. 557-559 3 p.

Research output: Research - peer-reviewLetter

3 Citations

Genome-wide gene expression profiling identifies overlap with malignant adrenocortical tumours and novel mechanisms of inefficient steroidogenesis in familial ACTH-independent macronodular adrenal hyperplasia

Gagliardi, L., Ling, K. H., Kok, C. H., Carolan, J., Brautigan, P., Kenyon, R., D'Andrea, R. J., Van Der Hoek, M., Hahn, C. N., Torpy, D. J. & Scott, H. S. Jun 2012 In : Endocrine-Related Cancer. 19, 3

Research output: Research - peer-reviewLetter

2011
13 Citations

The tyrosine kinase inhibitor dasatinib (SPRYCEL) inhibits chondrocyte activity and Proliferation

Vandyke, K., Fitter, S. & Zannettino, A. C. W. Feb 2011 In : Blood Cancer Journal. 1, 2, e2

Research output: Research - peer-reviewLetter

2010
8 Citations

Gene expression analysis reveals HOX gene upregulation in trisomy 8 AML

Kok, C. H., Brown, A. L., Ekert, P. G. & D'Andrea, R. J. 2010 In : Leukemia. 24, 6, p. 1239-1243 5 p.

Research output: Research - peer-reviewLetter

9 Citations
22 Citations

Nilotinib-mediated inhibition of ABCB1 increases intracellular concentration of dasatinib in CML cells: Implications for combination TKI therapy

Hiwase, D. K., White, D., Zrim, S., Saunders, V., Melo, J. V. & Hughes, T. P. 2010 In : Leukemia. 24, 3, p. 658-660 3 p.

Research output: Research - peer-reviewLetter

31 Citations

Re: Protection from right-and left-sided colorectal neoplasms after colonoscopy: Population-based study

Worthley, D. L., Hewett, D. G., Spring, K. J., Whitehall, V. L. J. & Leggett, B. A. Jul 2010 In : Journal of the National Cancer Institute. 102, 13, 1 p.

Research output: Research - peer-reviewLetter

2009
20 Citations

Nilotinib inhibits the Src-family kinase LCK and T-cell function in vitro

Blake, S. J., Lyons, A. B. & Hughes, T. P. Mar 2009 In : Journal of Cellular and Molecular Medicine. 13, 3, p. 599-601 3 p.

Research output: Research - peer-reviewLetter

2008
3 Citations

Daclizumab has poor efficacy in steroid-refractory severe acute graft-versus-host disease: A single centre experience with 12 allograft patients [2]

Hui, C. H., Sia, H., Mangos, H., Horvath, N., Lee, H., Lewis, I., Hughes, T., To, L. B. & Bardy, P. Feb 2008 In : Bone Marrow Transplantation. 41, 4, p. 409-410 2 p.

Research output: Research - peer-reviewLetter

2007
4 Citations

Participant satisfaction with fecal occult blood test screening for colorectal cancer [3]

Worthley, D. L., Cole, S. R., Mehaffey, S., Roosa, N. M., Smith, A., Turnbull, D. & Young, G. P. 2007 In : Journal of Gastroenterology and Hepatology (Australia). 22, 1, p. 142-143 2 p.

Research output: Research - peer-reviewLetter

2005
2 Citations

Fecal DNA for colorectal-cancer screening [3] (multiple letters)

Frossard, J. L., De Peyer, R., Worthley, D. L., Cole, S. R., Young, G. P., Imperiale, T. F., Ransohoff, D. F. & Itzkowitz, S. H. 31 Mar 2005 In : New England Journal of Medicine. 352, 13, p. 1384-1385 2 p.

Research output: Research - peer-reviewLetter

1 Citations

Mannose-binding lectin and liver transplantation [2] (multiple letters)

Worthley, D. L., Bardy, P. G., Angus, P., Harley, H., Mullighan, C. G., Bouwman, L. H., Terpstra, O. T., Schaapherder, A. F. M., Roos, A., Berger, S. P., Daha, M. R., De Knijff, P., Van Hoek, B., Verspaget, H. W., Frölich, M., Van Der Slik, A. R., Doxiadis, I. I. & Roep, B. O. 2005 In : Gastroenterology. 129, 5, p. 1805-1806 2 p.

Research output: Research - peer-reviewLetter

2004
1 Citations

Identification and Clinical Relevance of Receptor Activator of Nuclear Factor κB Ligand Expression of Myeloma Cells [2] (multiple letters)

Heider, U., Zavrski, I., Jakob, C., Fleissner, C., Sezer, O., Zannettino, A. C. W., Pan, B., Farrugia, A. N., Atkins, G. J. & Bik To, L. 15 Jan 2004 In : Cancer Research. 64, 2, p. 773-775 3 p.

Research output: Research - peer-reviewLetter

2003
2 Citations

Gastric hemorrhage as a late complication of splenic artery aneurysm repair: A dramatic way to vent one's spleen [1]

Worthley, D. L., Rayner, C. K., Devitt, P. G. & Fraser, R. 1 May 2003 In : Journal of Gastroenterology and Hepatology (Australia). 18, 5, p. 604-605 2 p.

Research output: Research - peer-reviewLetter