Research Output

2019

Sex differences in corneal neovascularization in response to superficial corneal cautery in the rat

Irani, Y., Pulford, E., Mortimer, L., Irani, S., Butler, L., Klebe, S. & Williams, K., 3 Sep 2019, In : PloS one. 14, 9, e0221566.

Research output: Contribution to journalArticle

1 Citation (Scopus)

The correlation between optical coherence tomography retinal shape irregularity and axial length

Lake, S., Bottema, M., Williams, K. & Reynolds, K., 1 Jan 2019, In : PloS one. 14, 12, e0227207.

Research output: Contribution to journalArticle

The intravitreal injection pain study: a randomized control study comparing subjective pain with injection technique

Crabb, M. G., Liu, E., Freeman, A., Hsu, T., Supramaniam, D., Kaidonis, G., Glading, J., Keane, M., Cugati, S., Lake, S. R., Saha, N., Landers, J. & Craig, J. E., 1 Dec 2019, In : Acta Ophthalmologica. 97, 8, p. e1153-e1154

Research output: Contribution to journalLetter

2018

DNA methylation at the 9p21 glaucoma susceptibility locus is associated with normal-tension glaucoma

Burdon, K. P., Awadalla, M. S., Mitchell, P., Wang, J. J., White, A., Keane, M., Souzeau, E., Graham, S. L., Goldberg, I., Healey, P. R., Landers, J., Mills, R. A. D., Best, S., Hewitt, A. W., Sharma, S. & Craig, J. E., 4 Mar 2018, In : Ophthalmic Genetics. 39, 2, p. 221-227 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Emerging diagnostic tests for vitreoretinal lymphoma: a review

Dawson, A. C., Williams, K., Appukuttan, B. & Smith, J. R., 1 Nov 2018, In : Clinical and Experimental Ophthalmology. 46, 8, p. 945-954 10 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Identification and In Vitro Expansion of Buccal Epithelial Cells

Ghaemi, S. R., Delalat, B., Harding, F. J., Irani, Y., Williams, K. & Voelcker, N. H., 1 Jun 2018, In : Cell Transplantation. 27, 6, p. 957-966 10 p.

Research output: Contribution to journalArticle

2017

An anti-VEGF-B antibody fragment induces regression of pre-existing blood vessels in the rat cornea

Irani, Y., Scotney, P. D., Klebe, S., Mortimer, L. A., Nash, A. D. & Williams, K., 1 Jul 2017, In : Investigative Ophthalmology and Visual Science. 58, 9, p. 3404-3413 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Is there evidence for a surgeon learning curve for endothelial keratoplasty in Australia?

on behalf of Contributors to the Australian Corneal Graft Registry, 1 Aug 2017, In : Clinical and Experimental Ophthalmology. 45, 6, p. 575-583 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Oral Mucosal Epithelial Cells Grown on Porous Silicon Membrane for Transfer to the Rat Eye

Irani, Y., Klebe, S., McInnes, S. J. P., Jasieniak, M., Voelcker, N. H. & Williams, K., 1 Dec 2017, In : Scientific Reports. 7, 1, 10042.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

A comparison of endothelial and penetrating keratoplasty outcomes following failed penetrating keratoplasty: A registry study

Keane, M., Galettis, R. A., Mills, R. A. D., Coster, D. J. & Williams, K., 1 Nov 2016, In : British Journal of Ophthalmology. 100, 11, p. 1569-1575 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2015

A novel pressed porous silicon-polycaprolactone composite as a dual-purpose implant for the delivery of cells and drugs to the eye

Irani, Y., Tian, Y., Wang, M., Klebe, S., McInnes, S. J., Voelcker, N. H., Coffer, J. L. & Williams, K., 1 Oct 2015, In : Experimental Eye Research. 139, p. 123-131 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Surface engineering of porous silicon to optimise therapeutic antibody loading and release

McInnes, S. J. P., Turner, C. T., Al-Bataineh, S. A., Airaghi Leccardi, M. J. I., Irani, Y., Williams, K., Cowin, A. J. & Voelcker, N. H., 28 May 2015, In : Journal of Materials Chemistry B. 3, 20, p. 4123-4133 11 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2014

Deep anterior lamellar keratoplasty versus penetrating keratoplasty for treating keratoconus

Keane, M., Coster, D., Ziaei, M. & Williams, K., 22 Jul 2014, In : Cochrane Database of Systematic Reviews. 2014, 7, CD009700.

Research output: Contribution to journalReview article

57 Citations (Scopus)

Predictive genetic testing experience for myocilin primary open-angle glaucoma using the Australian and New Zealand Registry of Advanced Glaucoma

Souzeau, E., Glading, J., Keane, M., Ridge, B., Zhou, T., Burdon, K. P. & Craig, J. E., 1 Jan 2014, In : Genetics in Medicine. 16, 7, p. 558-563 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2013

Co-expression of a scFv antibody fragment and a reporter protein using lentiviral shuttle plasmid containing a self-processing furin-2A sequence

Appleby, S. L., Irani, Y., Mortimer, L. A., Brereton, H. M., Klebe, S., Keane, M., Cowan, P. J. & Williams, K., 17 Sep 2013, In : Journal of Immunological Methods. 397, 1-2, p. 61-65 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2012

Comparison of Stain-Free gels with traditional immunoblot loading control methodology

Colella, A. D., Chegenii, N., Tea, M. N., Gibbins, I. L., Williams, K. & Chataway, T. K., 15 Nov 2012, In : Analytical Biochemistry. 430, 2, p. 108-110 3 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)
2010

Evaluation of mesoporous silicon/polycaprolactone composites as ophthalmic implants

Kashanian, S., Harding, F., Irani, Y., Klebe, S., Marshall, K., Loni, A., Canham, L., Fan, D., Williams, K., Voelcker, N. H. & Coffer, J. L., 1 Jan 2010, In : Acta Biomaterialia. 6, 9, p. 3566-3572 7 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Hereditary influences in oxygen-induced retinopathy in the rat

Van Wijngaarden, P., Brereton, H. M., Coster, D. J. & Williams, K., 1 Feb 2010, In : Documenta Ophthalmologica. 120, 1, p. 87-97 11 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Patients' knowledge and perception on optic neuritis management before and after an information session

Matti, A. I., Keane, M., McCarl, H., Klaer, P. & Chen, C. S., 21 Apr 2010, In : BMC Ophthalmology. 10, 1, 7.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2009

Mechanisms of corneal allograft rejection and regional immunosuppression

Coster, D. J., Jessup, C. F. & Williams, K., 1 Jan 2009, In : Eye. 23, 10, p. 1894-1897 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Prospects for genetic modulation of corneal graft survival

Williams, K., Brereton, H. M. & Coster, D. J., 1 Jan 2009, In : Eye. 23, 10, p. 1904-1909 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The biocompatibility of porous silicon in tissues of the eye

Low, S. P., Voelcker, N. H., Canham, L. T. & Williams, K., 1 May 2009, In : Biomaterials. 30, 15, p. 2873-2880 8 p.

Research output: Contribution to journalArticle

238 Citations (Scopus)
2008

Experimental melanin-induced uveitis: Experimental model of human acute anterior uveitis

Smith, J. R., Rosenbaum, J. T. & Williams, K., 1 Apr 2008, In : Ophthalmic Research. 40, 3-4, p. 136-140 5 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)

PCR amplification of the functional immunoglobulin heavy chain variable gene from a hybridoma in the presence of two aberrant transcripts

Irani, Y., Tea, M., Tilton, R. G., Coster, D. J., Williams, K. & Brereton, H. M., 31 Jul 2008, In : Journal of Immunological Methods. 336, 2, p. 246-250 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2007

Kinetics of strain-dependent differential gene expression in oxygen-induced retinopathy in the rat

van Wijngaarden, P., Brereton, H. M., Gibbins, I. L., Coster, D. J. & Williams, K., 1 Oct 2007, In : Experimental Eye Research. 85, 4, p. 508-517 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Lentivirus-mediated gene transfer to the rat, ovine and human cornea

Parker, D. G. A., Kaufmann, C., Brereton, H. M., Anson, D. S., Francis-Staite, L., Jessup, C. F., Marshall, K., Tan, C., Koldej, R., Coster, D. J. & Williams, K., 1 May 2007, In : Gene Therapy. 14, 9, p. 760-767 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Single chain antibody fragments for ocular use produced at high levels in a commercial wheat variety

Brereton, H. M., Chamberlain, D., Yang, R., Tea, M., McNeil, S., Coster, D. J. & Williams, K., 1 May 2007, In : Journal of Biotechnology. 129, 3, p. 539-546 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

The immunobiology of corneal transplantation

Williams, K. & Coster, D. J., 1 Oct 2007, In : Transplantation. 84, 7, p. 806-813 8 p.

Research output: Contribution to journalReview article

73 Citations (Scopus)
2006

Evaluation of mammalian cell adhesion on surface-modified porous silicon

Low, S. P., Williams, K., Canham, L. T. & Voelcker, N. H., 1 Sep 2006, In : Biomaterials. 27, 26, p. 4538-4546 9 p.

Research output: Contribution to journalArticle

232 Citations (Scopus)
2005

Corneal graft rejection occurs despite Fas ligand expression and apoptosis of infiltrating cells

Williams, K., Standfield, S. D., Smith, J. R. & Coster, D. J., 1 May 2005, In : British Journal of Ophthalmology. 89, 5, p. 632-638 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

In vitro adenovirus mediated gene transfer to the human cornea

Jessup, C. F., Brereton, H. M., Coster, D. J. & Williams, K., 1 Jun 2005, In : British Journal of Ophthalmology. 89, 6, p. 658-661 4 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The impact of corneal allograft rejection on the long-term outcome of corneal transplantation

Coster, D. J. & Williams, K., 1 Jan 2005, In : American Journal of Ophthalmology. 140, 6, p. 1112-1122 11 p.

Research output: Contribution to journalArticle

130 Citations (Scopus)
2004

Gene therapy approaches to prolonging corneal allograft survival

Williams, K., Jessup, C. F. & Coster, D. J., 1 Jul 2004, In : Expert Opinion on Biological Therapy. 4, 7, p. 1059-1071 13 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)
2003

Centrifugation facilitates transduction of green fluorescent protein in human monocytes and macrophages by adenovirus at low multiplicity of infection

Mayne, G. C., Borowicz, R. A., Greeneklee, K. V. L., Finlay-Jones, J. J., Williams, K. & Hart, P. H., 1 Jan 2003, In : Journal of Immunological Methods. 278, 1-2, p. 45-56 12 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Management of high-risk corneal grafts

Coster, D. J. & Williams, K., 1 Jan 2003, In : Eye. 17, 8, p. 996-1002 7 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

The potential of antibody-based immunosuppressive agents for corneal transplantation

Thiel, M. A., Coster, D. J. & Williams, K., 1 Apr 2003, In : Immunology and cell biology. 81, 2, p. 93-105 13 p.

Research output: Contribution to journalReview article

18 Citations (Scopus)
2001

Prolongation of sheep corneal allograft survival by ex vivo transfer of the gene encoding interleukin-101

Klebe, S., Sykes, P. J., Coster, D. J., Krishnan, R. & Williams, K., 15 May 2001, In : Transplantation. 71, 9, p. 1214-1220 7 p.

Research output: Contribution to journalArticle

112 Citations (Scopus)

The long term outcome of limbal allografts: The search for surviving cells

Henderson, T. R. M., Coster, D. J. & Williams, K., 14 May 2001, In : British Journal of Ophthalmology. 85, 5, p. 604-609 6 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)
2000

Anti-rat ICAM-1 antibody does not influence the course of experimental melanin-induced uveitis

Smith, J. R., O'Rourke, L. M., Becker, M. D., Cao, M., Williams, K., Planck, S. R. & Rosenbaum, J. T., 1 Dec 2000, In : Current Eye Research. 21, 5, p. 906-912 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Current Australian practice in the prevention and management of corneal allograft rejection

Barker, N. H., Henderson, T. R. M., Ross, C. A., Coster, D. J. & Williams, K., 29 Nov 2000, In : Clinical and Experimental Ophthalmology. 28, 5, p. 357-360 4 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
1999

Experimental melanin-induced uveitis in the Fischer 344 rat is inhibited by anti-CD4 monoclonal antibody, but not by mannose-6-phosphate

Smith, J. R., Hart, P. H., Parish, C. R., Standfield, S. D., Coster, D. J. & Williams, K., 20 Jan 1999, In : Clinical and Experimental Immunology. 115, 1, p. 64-71 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

The new-generation therapeutic anti-CD25 monoclonal antibodies

Williams, K., Thiel, M. A. & Zola, H., 15 Nov 1999, In : Transplantation. 68, 9, p. 1228-1229 2 p.

Research output: Contribution to journalComment/debate

6 Citations (Scopus)
1995

Experimental orthotopic corneal xenotransplantation in the rat: Mechanisms of graft rejection

Larkin, D. F. P., Takano, T., Standfield, S. D. & Williams, K., 15 Sep 1995, In : Transplantation. 60, 5, p. 491-497 7 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

How successful is corneal transplantation? a report from the australian corneal graft register

Williams, K., Muehlberg, S. M., Lewis, R. F. & Coster, D. J., 1 Jan 1995, In : Eye (Basingstoke). 9, 2, p. 219-227 9 p.

Research output: Contribution to journalArticle

162 Citations (Scopus)

The host response in experimental corneal xenotransplantation

Larkin, D. F. P. & Williams, K., 1 Jan 1995, In : Eye (Basingstoke). 9, 2, p. 254-260 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Use of DNA polymorphisms and the polymerase chain reaction to examine the survival of a human limbal stem cell allograft

Williams, K., Brereton, H. M., Aggarwal, R., Sykes, P. J., Turner, D. R., Russ, G. R. & Coster, D. J., 1 Jan 1995, In : American Journal of Ophthalmology. 120, 3, p. 342-350 9 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)
1993

Clinical and experimental aspects of corneal transplantation

Williams, K. & Coster, D. J., 1 Jan 1993, In : Transplantation Reviews. 7, 1, p. 44-64 21 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Storage, surgery, outcome, and complications of corneal and conjunctival grafts

Williams, K., Davis, G. J. & Coster, D. J., 1 Jan 1993, In : Current Opinion in Ophthalmology. 4, 4, p. 75-83 9 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)
1992

Patterns of corneal graft rejection in the rabbit and reversal of rejection with monoclonal antibodies

Williams, K., Standfield, S. D., Wing, S. J., Barras, C. W., Mills, R. A., Comacchio, R. M. & Coster, D. J., 1 Jan 1992, In : Transplantation. 54, 1, p. 38-43 6 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
1991

Long-term Outcome after Corneal Transplantation: Visual Result and Patient Perception of Success

Williams, K., Ash, J. K., Pararajasegaram, P., Harris, S. & Coster, D. J., 1 Jan 1991, In : Ophthalmology. 98, 5, p. 651-657 7 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)